Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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B274957-10mg | 10mg | In stock | $162.90 | |
B274957-50mg | 50mg | In stock | $681.90 |
Non-competitive, irreversible protein tyrosine phosphatase (PTP) inhibitor
Synonyms | AC-36977 | DTXSID90424993 | malonic acid mono ethyl ester | 3,3-dimethyl-1H-benzo[g]indole-2,4,5-trione | CS-0019823 | BVT 948 | TCMDC-124224 | 4-Hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione | BAQXWJQSUXZVIP-UHFFFAOYSA-N | BVT.948 | 4-Hydroxy-3,3- |
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Specifications & Purity | ≥99% |
Biochemical and Physiological Mechanisms | Non-competitive, irreversible protein tyrosine phosphatase (PTP) inhibitor (IC 50 values are 0.9 (PTP1B), 1.7 (TCPTP), 0.09 (SHP-2), 1.5 (LAR) and 0.7 (YopH) μM). Active in vivo and cell-permeable. |
Storage Temp | Protected from light,Store at -20°C,Argon charged,Desiccated |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. |
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IUPAC Name | 3,3-dimethyl-1H-benzo[g]indole-2,4,5-trione |
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INCHI | InChI=1S/C14H11NO3/c1-14(2)9-10(15-13(14)18)7-5-3-4-6-8(7)11(16)12(9)17/h3-6H,1-2H3,(H,15,18) |
InChi Key | LLPBUXODFQZPFH-UHFFFAOYSA-N |
Canonical SMILES | CC1(C2=C(C3=CC=CC=C3C(=O)C2=O)NC1=O)C |
Isomeric SMILES | CC1(C2=C(C3=CC=CC=C3C(=O)C2=O)NC1=O)C |
PubChem CID | 6604934 |
Molecular Weight | 241.25 |
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Solubility | Soluble in DMSO to 50 mM and in ethanol to 20 mM |
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Sensitivity | light & moisture sensitive |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H317:May cause an allergic skin reaction |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. |