BW A4C - 98%, high purity , CAS No.106328-57-8

  • ≥98%
Item Number
B334615
Grouped product items
SKUSizeAvailabilityPrice Qty
B334615-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$130.90
B334615-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$234.90
B334615-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$627.90
B334615-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,128.90
B334615-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,031.90

a selective 5-LO (5-lipoxygenase) inhibitor

Basic Description

SynonymsBW A4C | 106328-57-8 | N-(3-phenoxycinnamyl)acetohydroxamic acid | BW4C | BW-A4C | BW-A 4C | BWA4C | N-hydroxy-N-[(E)-3-(3-phenoxyphenyl)prop-2-enyl]acetamide | CHEMBL314360 | Bwa 4C | Bwa-4C | N-Hydroxy-N-(3-(3-phenoxyphenyl)allyl)acetamide | Acetamide, N-hydroxy-N-(3-(3-phenox
Specifications & Purity≥98%
Biochemical and Physiological Mechanismswhite Selective 5-lipoxygenase (5-LOX) inhibitor. Inhibits synthesis of LTB4.
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads
Product Description

BW A4C is a selective 5-LO (5-lipoxygenase) inhibitor. BW A4C inhibits synthesis of LTB|4|.

Associated Targets(Human)

ALOX5 Tclin Arachidonate 5-lipoxygenase (30 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ALOX5AP Tchem Arachidonate 5-lipoxygenase-activating protein (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX5AP Tchem 5-lipoxygenase activating protein (3184 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Homo sapiens (32628 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U-937 (7138 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase (1258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

PTGES Prostaglandin E synthase (10 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cavia porcellus (23802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RBL-1 (51 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name N-hydroxy-N-[(E)-3-(3-phenoxyphenyl)prop-2-enyl]acetamide
INCHI InChI=1S/C17H17NO3/c1-14(19)18(20)12-6-8-15-7-5-11-17(13-15)21-16-9-3-2-4-10-16/h2-11,13,20H,12H2,1H3/b8-6+
InChi Key CEUDWZXMLMKPNN-SOFGYWHQSA-N
Canonical SMILES CC(=O)N(CC=CC1=CC(=CC=C1)OC2=CC=CC=C2)O
Isomeric SMILES CC(=O)N(C/C=C/C1=CC(=CC=C1)OC2=CC=CC=C2)O
PubChem CID 6438354
Molecular Weight 283.32

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in DMSO: 20 mg/mL
Sensitivitylight sensitive
Melt Point(°C)79.3-80.1° C (lit.)

Related Documents

Solution Calculators