C-170 - 98%, high purity , CAS No.346691-38-1

Item Number

C420025

• Specifications & Purity: ≥98%
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads

Product Description

C-170 is a potent and covalent inhibitor of STING. C-170 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). It can be used for autoinflammatory disease research.

In vitro activity:

In THP-1 cells, pretreated with STING-IN-2 (C-170;?0.5 μM) and stimulated with cGAMP.?STING-IN-2 (C-170) treatment decreases the IFNB1 and TNF mRNA levels, and also reduces the p-TBK1 levels