[¹¹C]GSK215083 , CAS No.887923-36-6, Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 6 receptor

Item Number
C613771
Grouped product items
SKUSizeAvailabilityPrice Qty
C613771-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$600.90
C613771-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90

Basic Description

SynonymsGSK-215083 C-11 | (Sup 11)C-GSK215083 | 11C-GSK215083 | (Sup 11)C-GSK-215083 | UNII-100MIC832U | 887923-36-6 | (11C)-GSK-215083 | 100MIC832U | [11C]GSK215083 | 3-(3-fluorophenyl)sulfonyl-8-(4-methylpiperazin-1-yl)quinoline | Quinoline, 3-((3-fluorophenyl)sulfonyl)-8-(4-(meth
Specifications & PurityMoligand™
GradeMoligand™
Action TypeANTAGONIST
Mechanism of actionAntagonist of 5-HT 2A receptor;Antagonist of 5-HT 6 receptor

Associated Targets(Human)

HTR2A Tclin 5-hydroxytryptamine receptor 2A (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR6 Tchem 5-hydroxytryptamine receptor 6 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR6 Tchem Serotonin 6 (5-HT6) receptor (9749 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 3-(3-fluorophenyl)sulfonyl-8-(4-methylpiperazin-1-yl)quinoline
INCHI InChI=1S/C20H20FN3O2S/c1-23-8-10-24(11-9-23)19-7-2-4-15-12-18(14-22-20(15)19)27(25,26)17-6-3-5-16(21)13-17/h2-7,12-14H,8-11H2,1H3/i1-1
InChi Key PXVJEDOZGDZJQY-BJUDXGSMSA-N
Canonical SMILES [11CH3]N1CCN(CC1)c1cccc2c1ncc(c2)S(=O)(=O)c1cccc(c1)F
Isomeric SMILES [11CH3]N1CCN(CC1)C2=CC=CC3=CC(=CN=C32)S(=O)(=O)C4=CC=CC(=C4)F
PubChem CID 11696674

Certificates

Certificate of Analysis(COA)

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Related Documents

References

1. Parker CA, Gunn RN, Rabiner EA, Slifstein M, Comley R, Salinas C, Johnson CN, Jakobsen S, Houle S, Laruelle M et al..  (2012)  Radiosynthesis and characterization of 11C-GSK215083 as a PET radioligand for the 5-HT6 receptor..  J Nucl Med,  53  (2): (295-303).  [PMID:22223878]

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