CA125 Mouse mAb - Primary antibody, for ELISA,CLIA various applications, from Human, generated in Rat, specific to Antibody recognizes human cancer antigen 125 (CA125), IgG1

    Application:
  • Capture Antibody
  • CLIA
  • ELISA
Features and benefits
  • Host species: Mouse
  • Species reactivity(Reacts with): Human
  • Isotype: Mouse IgG1
  • Clone Number: 4A5
  • Conjugation: Unconjugated
Item Number
Ab005528
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab005528-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$29.90
Ab005528-50μg
50μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$87.90
Ab005528-100μg
100μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$117.90
Ab005528-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$417.90

mAb(4A5), Mouse anti Human CA125 Antibody; Capture antibody, ELISA, CLIA; Unconjugated

Basic Description

Product NameCA125 Mouse mAb - Primary antibody, for ELISA,CLIA various applications, from Human, generated in Rat, specific to Antibody recognizes human cancer antigen 125 (CA125), IgG1
SynonymsCA-125 | MUC-16 | Ovarian cancer-related tumor marker CA125 | Ovarian carcinoma antigen CA125
Specifications & PurityExactAb™, Validated, Carrier Free, Azide Free, Lot by Lot
Host SpeciesRat
Host speciesMouse
SpecificityAntibody recognizes human cancer antigen 125 (CA125)
ApplicationELISA,CLIA
ImmunogenE. coli-derived recombinant human CA125
EpitopeDomain B+C(Epitope class OV197)
ConjugationUnconjugated
GradeAzide Free, Carrier Free, ExactAb™, Validated
Product Description

Monoclonal (4A5), Mouse anti Human CA125 Antibody could used as the capture antibody in ELISA, CLIA at 1.0 μg/mL.

Product Properties

Antibody TypePrimary antibody
ClonalityMonoclonal antibodies
IsotypeIgG1
Purification MethodProtein A Purified
Matched Pairs[Ab005524] CA125 Mouse Antibody as detection antibody in ELISA, CLIA.
SourceHybridoma supernatant
FormLiquid
ConcentrationLot by Lot
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStorage: -20℃ for long term storage. Avoid repeated freeze / thaw cycles.

Images

Relevance of detection results between aladdin Antibody Pair (Ab005528 & Ab005524) and Roche in CLIA

· Capture antibody: CA125 Mouse mAb (Ab005528) at 1.0 μg/mL.

· Detection antibody: CA125 Mouse mAb (Ab005524) at 1.0 μg/mL.

· Linear Range: 0.6-5000 U/mL, R2 ≥ 0.98.

Associated Targets(Human)

MUC16 Tbio Mucin-16 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Application

ApplicationDilution info
ELISA

1 μg/mL

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
ZJ23F0500226Certificate of AnalysisJun 05, 2023 Ab005528
ZJ23F0500244Certificate of AnalysisJun 05, 2023 Ab005528

Related Documents

References

1. Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K et al..  (2004)  Complete sequencing and characterization of 21,243 full-length human cDNAs..  Nat Genet,  36  (1): (40-5).  [PMID:14702039] [10.1021/op500134e]
2. Yin, B W BW and Lloyd, K O KO..  (2001)  Molecular cloning of the CA125 ovarian cancer antigen: identification as a new mucin, MUC16..  The Journal of biological chemistry,    (20):   [PMID:11369781]
3. O'Brien, T J TJ and 5 more authors..  ()  The CA 125 gene: an extracellular superstructure dominated by repeat sequences..  Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine,      [PMID:11786729]
4. O'Brien, Timothy J TJ, Beard, John B JB, Underwood, Lowell J LJ and Shigemasa, Kazushi K..  ()  The CA 125 gene: a newly discovered extension of the glycosylated N-terminal domain doubles the size of this extracellular superstructure..  Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine,      [PMID:12218296]
5. Kui Wong, Nyet N and 9 more authors..  (2003)  Characterization of the oligosaccharides associated with the human ovarian tumor marker CA125..  The Journal of biological chemistry,    (1):   [PMID:12734200]
6. Rump, Armin A and 6 more authors..  (2004)  Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion..  The Journal of biological chemistry,    (5):   [PMID:14676194]
7. Grimwood, Jane J and 97 more authors..  (2004)  The DNA sequence and biology of human chromosome 19..  Nature,    (1):   [PMID:15057824]
8. McLemore, Monica R MR and Aouizerat, Bradley B..  (2005)  Introducing the MUC16 gene: implications for prevention and early detection in epithelial ovarian cancer..  Biological research for nursing,      [PMID:15788735]
9. Argüeso, Pablo P, Tisdale, Ann A, Spurr-Michaud, Sandra S, Sumiyoshi, Mika M and Gipson, Ilene K IK..  (2006)  Mucin characteristics of human corneal-limbal epithelial cells that exclude the rose bengal anionic dye..  Investigative ophthalmology & visual science,      [PMID:16384952]

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