Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C102139-25mg | 25mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $22.90 | |
C102139-250mg | 250mg | In stock | $205.90 | |
C102139-1g | 1g | In stock | $738.90 | |
C102139-5g | 5g | In stock | $3,324.90 | |
C102139-25g | 25g | In stock | $14,959.90 | |
C102139-100g | 100g | In stock | $53,852.90 |
Protein tyrosine kinase and ornithine decarboxylase inhibitor
Synonyms | Caffeic acid phenethyl ester, >=97% (HPLC), powder | LS-14562 | Methanone, 1,1'-(1,2-cyclopropanediyl)bis[1-phenyl- | SR-01000075785-1 | SR-01000075785-6 | HMS3677D22 | Lopac0_000269 | EU-0100269 | HMS1791N22 | NCGC00093727-08 | NCGC00093727-16 | phenethy |
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Specifications & Purity | ≥97% |
Biochemical and Physiological Mechanisms | Caffeic acid phenethyl ester is a specific inhibitor of the nuclear transcription factor NF-κB.Protein tyrosine kinase and ornithine decarboxylase inhibitor. Caffeic acid derivative. Inhibits 5-lipoxygenase. Induces apoptosis. Modulates cellular redox sta |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
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IUPAC Name | 2-phenylethyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate |
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INCHI | InChI=1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-7+ |
InChi Key | SWUARLUWKZWEBQ-VQHVLOKHSA-N |
Canonical SMILES | C1=CC=C(C=C1)CCOC(=O)C=CC2=CC(=C(C=C2)O)O |
Isomeric SMILES | C1=CC=C(C=C1)CCOC(=O)/C=C/C2=CC(=C(C=C2)O)O |
WGK Germany | 3 |
RTECS | UD3334375 |
PubChem CID | 5281787 |
Molecular Weight | 284.31 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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J1930134 | Certificate of Analysis | Aug 07, 2023 | C102139 |
I2214222 | Certificate of Analysis | Aug 10, 2022 | C102139 |
I2214223 | Certificate of Analysis | Aug 10, 2022 | C102139 |
I2214224 | Certificate of Analysis | Aug 10, 2022 | C102139 |
I2214225 | Certificate of Analysis | Aug 10, 2022 | C102139 |
J1816044 | Certificate of Analysis | Aug 05, 2022 | C102139 |
Solubility | Soluble in ethyl acetate at 50mg/ml. Soluble in DMSO and ethanol. |
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Sensitivity | heat sensitive &light sensitive |
Melt Point(°C) | 127-131℃ |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | UD3334375 |
1. Zi-Chen Jia, Duo Liu, Hai-Di Ma, Yu-Hui Cui, Hui-Min Li, Xia Li, Ying-Jin Yuan. (2023) Yeast Metabolic Engineering for Biosynthesis of Caffeic Acid-Derived Phenethyl Ester and Phenethyl Amide. ACS Synthetic Biology, (15): [PMID:38016187] |
2. Chengjun Peng, Guichun Wang, Yuxiao Wang, Maomao Tang, Xiaodong Ma, Xiangwei Chang, Jian Guo, Shuangying Gui. (2022) Thermosensitive acetylated carboxymethyl chitosan gel depot systems sustained release caffeic acid phenethyl ester for periodontitis treatment. POLYMERS FOR ADVANCED TECHNOLOGIES, 34 (1): (155-165). [PMID:] |
3. Weichao Sun, Wei Xie, Dixi Huang, Yinxing Cui, Jiaji Yue, Qifei He, Luoyong Jiang, Jianyi Xiong, Wei Sun, Qian Yi. (2022) Caffeic acid phenethyl ester attenuates osteoarthritis progression by activating NRF2/HO‑1 and inhibiting the NF‑κB signaling pathway. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 50 (5): (1-14). [PMID:36102306] |
1. Zi-Chen Jia, Duo Liu, Hai-Di Ma, Yu-Hui Cui, Hui-Min Li, Xia Li, Ying-Jin Yuan. (2023) Yeast Metabolic Engineering for Biosynthesis of Caffeic Acid-Derived Phenethyl Ester and Phenethyl Amide. ACS Synthetic Biology, (15): [PMID:38016187] |
2. Chengjun Peng, Guichun Wang, Yuxiao Wang, Maomao Tang, Xiaodong Ma, Xiangwei Chang, Jian Guo, Shuangying Gui. (2022) Thermosensitive acetylated carboxymethyl chitosan gel depot systems sustained release caffeic acid phenethyl ester for periodontitis treatment. POLYMERS FOR ADVANCED TECHNOLOGIES, 34 (1): (155-165). [PMID:] |
3. Weichao Sun, Wei Xie, Dixi Huang, Yinxing Cui, Jiaji Yue, Qifei He, Luoyong Jiang, Jianyi Xiong, Wei Sun, Qian Yi. (2022) Caffeic acid phenethyl ester attenuates osteoarthritis progression by activating NRF2/HO‑1 and inhibiting the NF‑κB signaling pathway. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 50 (5): (1-14). [PMID:36102306] |