Basic Description

Synonyms	Calcium levofolinate (INN) \| MFCD08704249 \| L-Glutamic acid, N-(4-(((2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-, calcium salt (1:1), (S)- \| Calcium levofolinate \| UNII-778XL6VBS8 \| Isovorin (TN) \| Calcium levofolinate
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Levoleucovorin calcium is the calcium salt of Levoleucovorin, which is the enantiomerically active form of folinic acid.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Calcium Levofolinate is a calcium salt of folinic acid that is an adjuvant used in cancer chemotherapy

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

IUPAC Name	calcium;(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate
INCHI	InChI=1S/C20H23N7O7.Ca/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30;/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32);/q;+2/p-2/t12-,13-;/m0./s1
InChi Key	KVUAALJSMIVURS-QNTKWALQSA-L
Canonical SMILES	C1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Ca+2]
Isomeric SMILES	C1[C@@H](N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Ca+2]
PubChem CID	135500522
Molecular Weight	511.5

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3 results found

Lot Number	Certificate Type	Date	Item
K2108255	Certificate of Analysis	Aug 11, 2023	C129891
K2108256	Certificate of Analysis	Aug 11, 2023	C129891
K2108258	Certificate of Analysis	Aug 11, 2023	C129891

Solubility	DMSO <1 mg/mL Water 9 mg/mL Ethanol <1 mg/mL

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

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SKU	Size	Availability	Price
C129891-10mg	10mg	In stock	$9.90
C129891-50mg	50mg	In stock	$11.90
C129891-250mg	250mg	In stock	$48.90