Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C420784-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $160.90 |
Potent, cell-permeable calpain inhibitor
Synonyms | calpeptin | 117591-20-5 | N-Cbz-leu-nleu-al | Benzylcarbonyl-leu-nleu-H | CHEMBL92708 | CHEBI:3330 | 18X9FR245W | benzyl ((S)-4-methyl-1-oxo-1-(((S)-1-oxohexan-2-yl)amino)pentan-2-yl)carbamate | N-Benzyloxycarbonyl-L-leucylnorleucinal | benzyl N-[(2S)-4-methyl-1-oxo-1-[[(2 |
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Specifications & Purity | Moligand™, 10mM in DMSO |
Biochemical and Physiological Mechanisms | Potent, cell-permeable calpain inhibitor, a Ca 2+ -dependent protease. K i values are 34 and 52 nM for μ- and m-calpains, respectively. Demonstrates neuroprotective effects suggesting ability to cross the blood-brain barrier. |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
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IUPAC Name | benzyl N-[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxohexan-2-yl]amino]pentan-2-yl]carbamate |
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INCHI | InChI=1S/C20H30N2O4/c1-4-5-11-17(13-23)21-19(24)18(12-15(2)3)22-20(25)26-14-16-9-7-6-8-10-16/h6-10,13,15,17-18H,4-5,11-12,14H2,1-3H3,(H,21,24)(H,22,25)/t17-,18-/m0/s1 |
InChi Key | PGGUOGKHUUUWAF-ROUUACIJSA-N |
Canonical SMILES | CCCCC(C=O)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1 |
Isomeric SMILES | CCCC[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1 |
PubChem CID | 73364 |
Molecular Weight | 362.47 |
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