Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| C412007-100μg | 100μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $39.90 | |
| C412007-1mg | 1mg | In stock | $159.90 | |
| C412007-5mg | 5mg | In stock | $664.90 | |
| C412007-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,196.90 |
Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Camrelizumab (anti-PD-1), for Flow,ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR) various applications, specific to PDCD1, >95%, high purity, Human IgG4SP |
|---|---|
| Synonyms | SHR-1210; CD279 antigen; CD279; hPD-1; PD1; PD-1; PD1hPD-l; PDCD1; programmed cell death 1; programmed cell death protein 1; Protein PD-1; SLEB2; CD279 antibody; CD279 antigen antibody; hPD 1 antibody; hPD l antibody; hPD-1 antibody; hSLE1 antibody; PD 1 |
| Specifications & Purity | ExactAb™, Validated, Carrier Free, Low Endotoxin, Azide Free, Recombinant, ≥95%(SDS-PAGE&SEC), Lot by Lot |
| Specificity | PDCD1 |
| Application | Flow,ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR) |
| Conjugation | Unconjugated |
| Grade | Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | ANTAGONIST |
| Mechanism of action | ANTAGONIST of Programmed cell death protein 1 antagonist |
| Product Description | Information Camrelizumab is a potent anti-PD-1 /PD-L1 active molecule that can be used in cancer research, including non-small cell lung cancer, esophageal squamous cell carcinoma, Hodgkin lymphoma, and advanced liver cancer. Purity >95% (SDS-PAGE&SEC) Endotoxin Level < 1.0EU/mg |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | Human IgG4SP |
| Light Chain Type | kappa |
| SDS-PAGE | 26.6 kDa (Light Chain) & 52.7 kDa (Heavy Chain), under reducing conditions; 177.2 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Form | Liquid |
| Concentration | Lot by Lot |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle. |
| CAS | 1798286-48-2 |
Camrelizumab (anti-PD-1) (C412007) - Flow Cytometry
Flow Cytometry analysis of 5μg/mL PHA stimulated 3 days human peripheral blood lymphocytes labelling PD-1 (red) with Camrelizumab (anti-PD-1) (C412007) conjugated with biotin and detected with SA-PE (rp156250). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
Camrelizumab (anti-PD-1) (C412007) - Flow Cytometry
Flow Cytometry analysis of MOLT-4 cells labelling PD-1 (red) with Camrelizumab (anti-PD-1) (C412007). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Camrelizumab (anti-PD-1) (C412007) - SEC
The purity of Camrelizumab (anti-PD-1) (C412007) is more than 95% verified by HPLC.
Camrelizumab (anti-PD-1) (C412007) - ELISA
Immobilized TARGET at 2 μg/mL can bind Camrelizumab (anti-PD-1) (C412007) with the EC₅₀ of 8.25 ng/mL.
Camrelizumab (anti-PD-1) (C412007) - ELISA
Immobilized Recombinant Human PD-1 Protein (rp176241) at 1.0 μg/mL can bind Camrelizumab (anti-PD-1) (C412007) with the EC50 of 10.39 ng/mL.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| IMGT/mAb-DB | 659 |
|---|---|
| Reactome Reaction | R-HSA-9679421 |
| Reactome Drug | R-ALL-9679471 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0607389 | Certificate of Analysis | Jun 26, 2024 | C412007 |
| ZJ23F1202075 | Certificate of Analysis | Dec 20, 2023 | C412007 |
| ZJ23F1202074 | Certificate of Analysis | Dec 20, 2023 | C412007 |
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