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SKU

Size

Availability

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C107691-20mg

20mg

Available within 4-8 weeks(?)

$138.90

Basic Description

Synonyms	Capsaicin\|404-86-4\|(E)-Capsaicin\|Zostrix\|Qutenza\|CAPSAICINE\|Styptysat\|Axsain\|Isodecenoic acid vanillylamide\|Ausanil\|trans-Capsaicin\|E-CAPSAICIN\|Mioton\|NGX-4010\|trans-8-Methyl-N-vanillyl-6-nonenamide\|FEMA No. 3404\|Dolenon\|Ovocap\|(E)-8-Methyl-N-vanillyl-6-n
Specifications & Purity	Moligand™, analytical standard, ≥95%(HPLC), natrual
Biochemical and Physiological Mechanisms	Description: IC50 Value: 150 ?M (MTT assay in FaDu cells) [1] Capsaicin is the active component of chili peppers, which are plantsbelonging to the genus Capsicum. Capsaicin, as a member of the vanilloidfamily, binds to a recepto
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	analytical standard, Moligand™
Action Type	ACTIVATOR, CHANNEL BLOCKER
Mechanism of action	Activator of CFTR;Channel blocker of K v1.1;Channel blocker of K v1.2;Channel blocker of K v1.7;Channel blocker of K v3.1;Activator of TRPV1

Product Properties

ALogP	3.6

Associated Targets

CNDP2 Tbio Cytosolic non-specific dipeptidase 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP1A2 Tchem Cytochrome P450 1A2 0 Activities

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CNR2 Tchem Cannabinoid receptor 2 0 Activities

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DRD2 Tclin D(2) dopamine receptor 0 Activities

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DRD4 Tchem D(4) dopamine receptor 0 Activities

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CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

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ERBB2 Tclin Receptor tyrosine-protein kinase erbB-2 0 Activities

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GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 0 Activities

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ELANE Tclin Neutrophil elastase 0 Activities

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EGFR Tclin Epidermal growth factor receptor 0 Activities

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HMGCR Tclin 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0 Activities

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HDAC6 Tclin Histone deacetylase 6 0 Activities

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HRH1 Tclin Histamine H1 receptor 0 Activities

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SLC6A4 Tclin Sodium-dependent serotonin transporter 0 Activities

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TRPA1 Tclin Transient receptor potential cation channel subfamily A member 1 0 Activities

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SIGMAR1 Tclin Sigma non-opioid intracellular receptor 1 0 Activities

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TTR Tclin Transthyretin 0 Activities

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PDE4D Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0 Activities

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PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities

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LPAR1 Tchem Lysophosphatidic acid receptor 1 0 Activities

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CA2 Tclin Carbonic anhydrase 2 0 Activities

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DRD3 Tclin D(3) dopamine receptor 0 Activities

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CHRM3 Tclin Muscarinic acetylcholine receptor M3 0 Activities

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CHRM4 Tclin Muscarinic acetylcholine receptor M4 0 Activities

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ADRA2B Tclin Alpha-2B adrenergic receptor 0 Activities

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ADRA2C Tclin Alpha-2C adrenergic receptor 0 Activities

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HTR2A Tclin 5-hydroxytryptamine receptor 2A 0 Activities

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ADORA2A Tclin Adenosine receptor A2a 0 Activities

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ACHE Tclin Acetylcholinesterase 0 Activities

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ADRA1A Tclin Alpha-1A adrenergic receptor 0 Activities

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AR Tclin Androgen receptor 0 Activities

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AKR1B1 Tclin Aldose reductase 0 Activities

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ADORA1 Tclin Adenosine receptor A1 0 Activities

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HTR1A Tclin 5-hydroxytryptamine receptor 1A 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADORA3 Tchem Adenosine receptor A3 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR3A Tclin 5-hydroxytryptamine receptor 3A 0 Activities

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HTR6 Tchem 5-hydroxytryptamine receptor 6 0 Activities

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HTR2B Tclin 5-hydroxytryptamine receptor 2B 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

BCHE Tclin Cholinesterase 0 Activities

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EDNRA Tclin Endothelin-1 receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRD1 Tclin Delta-type opioid receptor 0 Activities

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OPRK1 Tclin Kappa-type opioid receptor 0 Activities

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OPRM1 Tclin Mu-type opioid receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NOS2 Tchem Nitric oxide synthase, inducible 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TACR1 Tclin Substance-P receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NOS1 Tchem Nitric oxide synthase, brain 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
INCHI	InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+
InChi Key	YKPUWZUDDOIDPM-SOFGYWHQSA-N
Canonical SMILES	CC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC
Isomeric SMILES	CC(C)/C=C/CCCCC(=O)NCC1=CC(=C(C=C1)O)OC
WGK Germany	3
RTECS	RA8530000
PubChem CID	1548943
UN Number	2811
Molecular Weight	305.41
Beilstein	2816484

Database links

PubChem CID	1548943
ChEBI	CHEBI:3374
CAS Registry No.	404-86-4
ChEMBL Ligand	CHEMBL294199
BindingDB Ligand	20461
Wikipedia	Capsaicin
RCSB PDB Ligand	4DY
DrugCentral Ligand	3064

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

4 results found

Lot Number	Certificate Type	Date	Item
E2429045	Certificate of Analysis	Jun 03, 2024	C107691
D2314710	Certificate of Analysis	Apr 23, 2023	C107691
F2121091	Certificate of Analysis	Mar 16, 2023	C107691
B2226418	Certificate of Analysis	Mar 04, 2022	C107691

Chemical and Physical Properties

Flash Point(°F)	235.4 °F
Flash Point(°C)	113℃
Melt Point(°C)	65°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS05, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H301:Toxic if swallowed H302:Harmful if swallowed H318:Causes serious eye damage
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P332+P317:If skin irritation occurs: Get medical help.
WGK Germany	3
RTECS	RA8530000
Merck Index	1768

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Capsaicin - analytical standard，≥95%(HPLC),natrual, high purity , CAS No.404-86-4, Activator of CFTR;Channel blocker of K v1.1;Channel blocker of K v1.2;Channel blocker of K v1.7;Channel blocker of K v3.1;Activator of TRPV1