Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C107691-20mg | 20mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $138.90 |
Synonyms | CAPSAICIN (USP-RS) | 6-Nonenamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-8-methyl-, (E)- | N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide | NCGC00017337-02 | N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide | (6E)-N-{[4-hydroxy-3-(methylox |
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Specifications & Purity | Moligand™, analytical standard, ≥95%(HPLC), natrual |
Biochemical and Physiological Mechanisms | Description: |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | analytical standard, Moligand™ |
Action Type | ACTIVATOR, CHANNEL BLOCKER |
Mechanism of action | Activator of CFTR;Channel blocker of K v1.1;Channel blocker of K v1.2;Channel blocker of K v1.7;Channel blocker of K v3.1;Activator of TRPV1 |
ALogP | 3.6 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide |
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INCHI | InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+ |
InChi Key | YKPUWZUDDOIDPM-SOFGYWHQSA-N |
Canonical SMILES | CC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC |
Isomeric SMILES | CC(C)/C=C/CCCCC(=O)NCC1=CC(=C(C=C1)O)OC |
WGK Germany | 3 |
RTECS | RA8530000 |
PubChem CID | 1548943 |
UN Number | 2811 |
Molecular Weight | 305.41 |
Beilstein | 2816484 |
PubChem CID | 1548943 |
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ChEBI | CHEBI:3374 |
CAS Registry No. | 404-86-4 |
ChEMBL Ligand | CHEMBL294199 |
BindingDB Ligand | 20461 |
Wikipedia | Capsaicin |
RCSB PDB Ligand | 4DY |
DrugCentral Ligand | 3064 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
E2429045 | Certificate of Analysis | Jun 03, 2024 | C107691 |
D2314710 | Certificate of Analysis | Apr 23, 2023 | C107691 |
F2121091 | Certificate of Analysis | Mar 16, 2023 | C107691 |
B2226418 | Certificate of Analysis | Mar 04, 2022 | C107691 |
Flash Point(°F) | 235.4 °F |
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Flash Point(°C) | 113℃ |
Melt Point(°C) | 65°C |
Pictogram(s) | GHS06, GHS05, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H301:Toxic if swallowed H302:Harmful if swallowed H318:Causes serious eye damage |
Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P332+P317:If skin irritation occurs: Get medical help. |
WGK Germany | 3 |
RTECS | RA8530000 |
Merck Index | 1768 |
1. Yamei Ma, Zhen Zhang, Shengchao Gao, Yue Zhan, Zihao Wei, Ying Liu. (2023) The efficient Congo red decolorization coupled with electricity generation via G. sulfurreducens based on microbial fuel cells. Journal of Environmental Chemical Engineering, 11 (1): (111296). [PMID:26449471] [10.1016/j.jece.2023.111296] |
2. Yiding ZHAO, Xiaoning YAN, Shanshan JIANG, Yong LIU, Chun DONG, Huiyan CHI, Chaoyi MAO. (2023) Zhenxin Anshen formula ameliorates atopic der-matitis-like skin dysfunction in mice and regulation of transient receptor potential vanilloid 1 and transient receptor potential ankyrin 1 in Neural pathways.. Journal of Traditional Chinese Medicine, 43 (5): (887-896). [PMID:37679976] [10.19852/j.cnki.jtcm.20230802.003] |
3. Xing Yan, Ming-Jun Zhu. (2023) Enhanced bioelectricity generation in thermophilic microbial fuel cell with lignocellulose as an electron donor by resazurin-mediated electron transfer. BIORESOURCE TECHNOLOGY, 388 (8): (129764). [PMID:37722540] [10.1016/j.biortech.2023.129764] |
4. Xu Rui-Qi, Ma Ling, Chen Timson, Zhang Wei-Xiong, Chang Kuan, Wang Jing. (2023) Sophorolipid inhibits histamine-induced itch by decreasing PLC/IP3R signaling pathway activation and modulating TRPV1 activity. Scientific Reports, 13 (1): (1-13). [PMID:37198299] [10.1038/s41598-023-35158-9] |
5. Lingling Qin, Jie Cao, Dan Lin, Shihao Xu, Yucheng Li, Changlong Jiang. (2023) A Strecker-like reaction triggering fluorescent sensing platform for enzyme-free and visual quantitative monitoring of carbamates. CHEMICAL ENGINEERING JOURNAL, 464 (142550). [PMID:] [10.1016/j.cej.2023.142550] |
6. Yiwen Zhu, Xiang Li, Shui Jiang, Yin Zhang, Lihua Zhang, Yuan Liu. (2023) Multi-dimensional pungency and sensory profiles of powder and oil of seven chili peppers based on descriptive analysis and Scoville heat units. FOOD CHEMISTRY, 411 (135488). [PMID:36681025] [10.1016/j.foodchem.2023.135488] |
7. Sijun Wu, Long Wang, Guoming Zhou, Chao Liu, Zhongrui Ji, Zheng Li, Wenlong Li. (2023) Strategies for the content determination of capsaicin and the identification of adulterated pepper powder using a hand-held near-infrared spectrometer. FOOD RESEARCH INTERNATIONAL, 163 (112192). [PMID:36596130] [10.1016/j.foodres.2022.112192] |
8. Yun Ning, Lu Chaoqun, Sun Tian, Xu Baocai, Song Yushen, Zong Zibing, Chen Kangwen, Huang Ganhui, Chen Xingguang, Gu Qianhui. (2023) High Sensitivity Detection of Capsaicin in Red Pepper Oil Based on Reduced Graphene Oxide Enhanced by β-Cyclodextrin. Food Analytical Methods, 16 (2): (318-329). [PMID:] [10.1007/s12161-022-02415-y] |
9. Li Junkui, Zuo Min, Zhang Wen, Zou Xiaobo, Sun Zongbao. (2022) Diazo Coupling-Based Ultrasensitive SERS Detection of Capsaicin and Its Application in Identifying Gutter Oil. Food Analytical Methods, 15 (12): (3468-3478). [PMID:] [10.1007/s12161-022-02372-6] |
10. Susu Lin, Bingbing Ma, Qilin Gao, Jian Yang, Gang Lai, Runhao Lin, Bingxian Yang, Bing-Nan Han, Lian-Hua Xu. (2022) The 16α-Hydroxylation of Progesterone by Cytochrome P450 107X1 from Streptomyces avermitilis. CHEMISTRY & BIODIVERSITY, 19 (5): (e202200177). [PMID:35426465] [10.1002/cbdv.202200177] |
11. Mengqing Xu, Jin Zhang, Yongli Mu, Mohamed Frahat Foda, Heyou Han. (2022) Activation of TRPV1 by capsaicin-loaded CaCO3 nanoparticle for tumor-specific therapy. BIOMATERIALS, 284 (121520). [PMID:35436739] [10.1016/j.biomaterials.2022.121520] |
12. Fang Xiao, Duan Rongshuai. (2022) Highly Sensitive Capsaicin Electrochemical Sensor Based on Bimetallic Metal-Organic Framework Nanocage. Frontiers in Chemistry, 10 [PMID:35242739] [10.3389/fchem.2022.822619] |
13. Yan Jia, Xie Shujie, Xia Qin, Li Xiang, Chen Shuhuai, Shen Jia. (2022) Engineering of combination drug delivery of pH/reduction response potential nanocarrier for the treatment of liver cancer. Applied Nanoscience, 12 (5): (1545-1556). [PMID:] [10.1007/s13204-021-02312-6] |
14. Zi Ye, Zhixun Shang, Shiyao Zhang, Meiqi Li, Xuetin Zhang, Hongbing Ren, Xiaosong Hu, Junjie Yi. (2022) Dynamic analysis of flavor properties and microbial communities in Chinese pickled chili pepper (Capsicum frutescens L.): A typical industrial-scale natural fermentation process. FOOD RESEARCH INTERNATIONAL, 153 (110952). [PMID:35227474] [10.1016/j.foodres.2022.110952] |
15. Xinghao Liu, Zhaoguang Yang, Wenxiu Zhu, Ying Yang, Haipu Li. (2022) Catalytic ozonation of chloramphenicol with manganese-copper oxides/maghemite in solution: Empirical kinetics model, degradation pathway, catalytic mechanism, and antibacterial activity. JOURNAL OF ENVIRONMENTAL MANAGEMENT, 302 (114043). [PMID:34735833] [10.1016/j.jenvman.2021.114043] |
16. Yuan Yin, Dong Fei-Xue, Liu Xu, Xiao Hong-Bin, Zhou Zhong-Guang. (2021) Liquid Chromatograph-Mass Spectrometry-Based Non-targeted Metabolomics Discovery of Potential Endogenous Biomarkers Associated With Prostatitis Rats to Reveal the Effects of Magnoflorine. Frontiers in Pharmacology, 12 [PMID:34790120] [10.3389/fphar.2021.741378] |
17. Di Wu, Ran Duan, Lan Tang, Dian Zhou, Zhen Zeng, Wen Wu, Jie Hu, Qiaomei Sun. (2022) In-vitro binding analysis and inhibitory effect of capsaicin on lipase. LWT-FOOD SCIENCE AND TECHNOLOGY, 154 (112674). [PMID:] [10.1016/j.lwt.2021.112674] |
18. Zi Ye, Zhixun Shang, Meiqi Li, Yonghan Qu, Hongjin Long, Junjie Yi. (2020) Evaluation of the physiochemical and aromatic qualities of pickled Chinese pepper (Paojiao) and their influence on consumer acceptability by using targeted and untargeted multivariate approaches. FOOD RESEARCH INTERNATIONAL, 137 (109535). [PMID:33233164] [10.1016/j.foodres.2020.109535] |
19. Zhigang Liu, Xianli Wang, Jie Chen, Jimin Gao, Shihua Yu, Xiuguo Wang. (2020) Three-template magnetic molecular imprinted polymer for the rapid separation and specific recognition of illegal cooking oil markers. MICROCHEMICAL JOURNAL, 157 (105052). [PMID:] [10.1016/j.microc.2020.105052] |
20. Fuchao Zhan, Shuang Ding, Wenya Xie, Xiao Zhu, Jiangnan Hu, Jun Gao, Bin Li, Yijie Chen. (2020) Towards understanding the interaction of β-lactoglobulin with capsaicin: Multi-spectroscopic, thermodynamic, molecular docking and molecular dynamics simulation approaches. FOOD HYDROCOLLOIDS, 105 (105767). [PMID:] [10.1016/j.foodhyd.2020.105767] |
21. Jiayi Zhao, Feng Wei, Weili Xu, Xiaojun Han. (2020) Enhanced antibacterial performance of gelatin/chitosan film containing capsaicin loaded MOFs for food packaging. APPLIED SURFACE SCIENCE, 510 (145418). [PMID:] [10.1016/j.apsusc.2020.145418] |
22. Mingming Zhu, Xi Yu, Zongmei Zheng, Jiaming Huang, Xuepan Yang, Hongfei Shi. (2019) Capsaicin suppressed activity of prostate cancer stem cells by inhibition of Wnt/β-catenin pathway. PHYTOTHERAPY RESEARCH, 34 (4): (817-824). [PMID:31782192] [10.1002/ptr.6563] |
23. Xiang Shen, Peng Liu, Shubiao Xia, Jianjun Liu, Rui Wang, Hua Zhao, Qiuju Liu, Jiao Xu, Fan Wang. (2019) Anti-Fouling and Anti-Bacterial Modification of Poly(vinylidene fluoride) Membrane by Blending with the Capsaicin-Based Copolymer. Polymers, 11 (2): (323). [PMID:30960307] [10.3390/polym11020323] |
24. Jiajia Sun, Liqiang Liu, Shanshan Song, Gang Cui, Hua Kuang. (2018) Development of an immunochromatographic strip assay for three major capsaicinoids based on an ultrasensitive monoclonal antibody. FOOD AND AGRICULTURAL IMMUNOLOGY, [PMID:] [10.1080/09540105.2018.1490394] |
25. Zhigang Liu, Shihua Yu, Shuping Xu, Bing Zhao, Weiqing Xu. (2017) Ultrasensitive Detection of Capsaicin in Oil for Fast Identification of Illegal Cooking Oil by SERRS. ACS Omega, 2 (11): (8401–8406). [PMID:31457378] [10.1021/acsomega.7b01457] |
26. Wang Yan, Huang Bin-Bin, Dai Wan-Lin, Xu Bin, Wu Tian-Liang, Ye Jia-Ping, Ye Jian-Shan. (2017) Sensitive Electrochemical Capsaicin Sensor Based on a Screen Printed Electrode Modified with Poly(sodium 4-styrenesulfonate) Functionalized Graphite. ANALYTICAL SCIENCES, 33 (7): (793-799). [PMID:28690256] [10.2116/analsci.33.793] |
27. Yan Wang, Binbin Huang, Wanlin Dai, Jianshan Ye, Bin Xu. (2016) Sensitive determination of capsaicin on Ag/Ag2O nanoparticles/reduced graphene oxide modified screen-printed electrode. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 776 (93). [PMID:] [10.1016/j.jelechem.2016.06.031] |
28. Ping Qi, Zhihao Lin, Jiaxu Li, ChengLong Wang, WeiWei Meng, Hong Hong, Xuewu Zhang. (2014) Development of a rapid, simple and sensitive HPLC-FLD method for determination of rhodamine B in chili-containing products. FOOD CHEMISTRY, 164 (98). [PMID:24996311] [10.1016/j.foodchem.2014.05.036] |
29. Aihua Zhang,Huiyu Wang,Hui Sun,Yue Zhang,Na An,Guangli Yan,Xiangcai Meng,Xijun Wang. (2015-08-25) Metabolomics strategy reveals therapeutical assessment of limonin on nonbacterial prostatitis.. Food & function, 6 ((11)): (3540-3549). [PMID:26302114] |
30. Hui Sun,Huiyu Wang,Aihua Zhang,Guangli Yan,Yue Zhang,Na An,Xijun Wang. (2015-01-15) Berberine ameliorates nonbacterial prostatitis via multi-target metabolic network regulation.. Omics : a journal of integrative biology, 19 ((3)): (186-195). [PMID:25588034] |
1. Yamei Ma, Zhen Zhang, Shengchao Gao, Yue Zhan, Zihao Wei, Ying Liu. (2023) The efficient Congo red decolorization coupled with electricity generation via G. sulfurreducens based on microbial fuel cells. Journal of Environmental Chemical Engineering, 11 (1): (111296). [PMID:26449471] [10.1016/j.jece.2023.111296] |
2. Yiding ZHAO, Xiaoning YAN, Shanshan JIANG, Yong LIU, Chun DONG, Huiyan CHI, Chaoyi MAO. (2023) Zhenxin Anshen formula ameliorates atopic der-matitis-like skin dysfunction in mice and regulation of transient receptor potential vanilloid 1 and transient receptor potential ankyrin 1 in Neural pathways.. Journal of Traditional Chinese Medicine, 43 (5): (887-896). [PMID:37679976] [10.19852/j.cnki.jtcm.20230802.003] |
3. Xing Yan, Ming-Jun Zhu. (2023) Enhanced bioelectricity generation in thermophilic microbial fuel cell with lignocellulose as an electron donor by resazurin-mediated electron transfer. BIORESOURCE TECHNOLOGY, 388 (8): (129764). [PMID:37722540] [10.1016/j.biortech.2023.129764] |
4. Xu Rui-Qi, Ma Ling, Chen Timson, Zhang Wei-Xiong, Chang Kuan, Wang Jing. (2023) Sophorolipid inhibits histamine-induced itch by decreasing PLC/IP3R signaling pathway activation and modulating TRPV1 activity. Scientific Reports, 13 (1): (1-13). [PMID:37198299] [10.1038/s41598-023-35158-9] |
5. Lingling Qin, Jie Cao, Dan Lin, Shihao Xu, Yucheng Li, Changlong Jiang. (2023) A Strecker-like reaction triggering fluorescent sensing platform for enzyme-free and visual quantitative monitoring of carbamates. CHEMICAL ENGINEERING JOURNAL, 464 (142550). [PMID:] [10.1016/j.cej.2023.142550] |
6. Yiwen Zhu, Xiang Li, Shui Jiang, Yin Zhang, Lihua Zhang, Yuan Liu. (2023) Multi-dimensional pungency and sensory profiles of powder and oil of seven chili peppers based on descriptive analysis and Scoville heat units. FOOD CHEMISTRY, 411 (135488). [PMID:36681025] [10.1016/j.foodchem.2023.135488] |
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