Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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D129539-1g | 1g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $9.90 | |
D129539-5g | 5g | In stock | $23.90 | |
D129539-10g | 10g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $36.90 | |
D129539-25g | 25g | In stock | $69.90 | |
D129539-100g | 100g | In stock | $249.90 | |
D129539-500g | 500g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,123.90 |
Synonyms | Carbamazepine (USAN:USP:INN:BAN:JAN) | CARBAMAZEPINE [USP MONOGRAPH] | CarbamazepineER | Carbazepine | NCGC00015234-11 | Tegretol | CARBAMAZEPINE (USP IMPURITY) | EINECS 206-062-7 | CARBAMAZEPINE [EP MONOGRAPH] | CBChromo1_000350 | HSDB 3019 | Carbamazepe |
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Specifications & Purity | Moligand™, ≥98% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ALLOSTERIC MODULATOR, BLOCKER |
Mechanism of action | Sodium channel alpha subunit blocker |
Product Description | Carbamazepine is an orally active pressure-sensitive sodium ion channel blocker with an IC50 of 131 μM. Carbamazepine blocks voltage gated Na+, Ca2+, and K+ channels, and is also a HDAC inhibitor (IC50: 2 μM). Carbamazepine is an anticonvulsant and can be used for research of epilepsy and neuropathic pain. |
ALogP | 2.5 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | benzo[b][1]benzazepine-11-carboxamide |
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INCHI | InChI=1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18) |
InChi Key | FFGPTBGBLSHEPO-UHFFFAOYSA-N |
Canonical SMILES | C1=CC=C2C(=C1)C=CC3=CC=CC=C3N2C(=O)N |
Isomeric SMILES | C1=CC=C2C(=C1)C=CC3=CC=CC=C3N2C(=O)N |
PubChem CID | 2554 |
Molecular Weight | 236.27 |
CAS Registry No. | 298-46-4 |
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Wikipedia | Carbamazepine |
PubChem CID | 2554 |
DrugBank Ligand | DB00564 |
ChEMBL Ligand | CHEMBL108 |
PEP | carbamazepine |
RCSB PDB Ligand | N6W |
DrugCentral Ligand | 489 |
GPCRdb Ligand | carbamazepine |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
C2429452 | Certificate of Analysis | Mar 12, 2024 | D129539 |
C2429443 | Certificate of Analysis | Mar 12, 2024 | D129539 |
C2429444 | Certificate of Analysis | Mar 12, 2024 | D129539 |
B2423672 | Certificate of Analysis | Jan 23, 2024 | D129539 |
H2413041 | Certificate of Analysis | Jan 23, 2024 | D129539 |
K2413095 | Certificate of Analysis | Jan 23, 2024 | D129539 |
B2423593 | Certificate of Analysis | Jan 23, 2024 | D129539 |
E2417046 | Certificate of Analysis | Jan 23, 2024 | D129539 |
B2423693 | Certificate of Analysis | Jan 23, 2024 | D129539 |
B2423678 | Certificate of Analysis | Jan 23, 2024 | D129539 |
B2423676 | Certificate of Analysis | Jan 23, 2024 | D129539 |
B2423675 | Certificate of Analysis | Jan 23, 2024 | D129539 |
L2304075 | Certificate of Analysis | Nov 03, 2022 | D129539 |
K2212435 | Certificate of Analysis | Nov 03, 2022 | D129539 |
K2212434 | Certificate of Analysis | Nov 03, 2022 | D129539 |
L2312022 | Certificate of Analysis | Nov 03, 2022 | D129539 |
K2212433 | Certificate of Analysis | Nov 03, 2022 | D129539 |
K2212431 | Certificate of Analysis | Nov 03, 2022 | D129539 |
J2311032 | Certificate of Analysis | Nov 03, 2022 | D129539 |
J2309067 | Certificate of Analysis | Nov 03, 2022 | D129539 |
H2321115 | Certificate of Analysis | Nov 03, 2022 | D129539 |
G2308213 | Certificate of Analysis | Nov 03, 2022 | D129539 |
G2308212 | Certificate of Analysis | Nov 03, 2022 | D129539 |
G2306116 | Certificate of Analysis | Nov 03, 2022 | D129539 |
I2226217 | Certificate of Analysis | Sep 28, 2022 | D129539 |
I2208367 | Certificate of Analysis | Sep 15, 2022 | D129539 |
G2208143 | Certificate of Analysis | Jul 11, 2022 | D129539 |
Solubility | DMSO 47 mg/mL Water <1 mg/mL Ethanol 18 mg/mL |
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Melt Point(°C) | 191 °C |
Pictogram(s) | GHS08, GHS07 |
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Signal | Danger |
Hazard Statements | H302:Harmful if swallowed H317:May cause an allergic skin reaction H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P284:[In case of inadequate ventilation] Wear respiratory protection. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately. |
Merck Index | 1781 |
Starting at $155.90
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4. Mengxi Tan, Xiaoshan Zheng, Wanchao Yu, Baoliang Chen, Chiheng Chu. (2023) Facet-Dependent Productions of Reactive Oxygen Species from Pyrite Oxidation. ENVIRONMENTAL SCIENCE & TECHNOLOGY, [PMID:38111081] [10.1021/acs.est.3c06105] |
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6. Lianxu Wang, Zhen Lei, Sining Yun, Xiaohuan Yang, Rong Chen. (2024) Quantitative structure-biotransformation relationships of organic micropollutants in aerobic and anaerobic wastewater treatments. SCIENCE OF THE TOTAL ENVIRONMENT, 912 (169170). [PMID:38072270] [10.1016/j.scitotenv.2023.169170] |
7. Kai Xuan, Taiguang Li, Yongmei Hao. (2024) Spatially separated noble-metal-free CdS photocatalyst with redox surface exposure for photodegradation of PPCPs and Cr (VI). CERAMICS INTERNATIONAL, 50 (3701). [PMID:21866213] [10.1016/j.ceramint.2023.11.122] |
8. Yahui Zhou, Xiaohua Cheng, Zijian Duan, Xin Liu, Huiyu Yang, Bo Deng. (2023) Flame-assisted combustion preparation of highly efficient black TiO2 microspheres photocatalysts under visible light. Journal of Environmental Chemical Engineering, 11 (20): (111301). [PMID:31031083] [10.1016/j.jece.2023.111301] |
9. Jinming Feng, Jincheng Mu, Qiong Peng, Yang Xiao, Baojun Liu. (2023) In situ interfacial engineering modulated adsorption and electron transfer boosting peroxymonosulfate activation for micro-contaminates degradation over CoOx nanosheet. CHEMICAL ENGINEERING JOURNAL, 476 (146724). [PMID:25996873] [10.1016/j.cej.2023.146724] |
10. Chao-Hai Gu, Song Wang, Ai-Yong Zhang, Chang Liu, Jun Jiang, Han-Qing Yu. (2023) Slow-release synthesis of Cu single-atom catalysts with the optimized geometric structure and density of state distribution for Fenton-like catalysis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 120 (43): (e2311585120). [PMID:37844255] [10.1073/pnas.2311585120] |
11. Zhendong Wang, Zhexin Zhu, Gangqiang Wang, Xiaoji Ma, Wangyang Lu. (2023) Iron (II) phthalocyanine loaded tourmaline efficiently activates PMS to degrade pharmaceutical contaminants under solar light. ENVIRONMENTAL TECHNOLOGY, (28): [PMID:35437123] [10.1080/09593330.2022.2064236] |
12. Gang Chu, Wangmin Wang, Yang Dou, Wenxiu Qin, Da Tian, Youbin Si. (2023) Contrasting impact of phosphorus dissolution on the sorption of bisphenol A and carbamazepine by phosphorus-rich chars. CHEMICAL ENGINEERING JOURNAL, 475 (19): (146370). [PMID:18957440] [10.1016/j.cej.2023.146370] |
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14. Dongqin Tan, Yi Liang, Ting Guo, Yue Wang, Yanying Li, Xiaoli Sun, Degao Wang. (2023) Dummy molecularly imprinted polymers-agarose gel mixed matrix membrane for extraction of amphetamine-type stimulants in wastewater and urine. JOURNAL OF CHROMATOGRAPHY A, 1708 (1): (464368). [PMID:37708673] [10.1016/j.chroma.2023.464368] |
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17. Yueling Yu, Jia Yang, Baogang Zhao, Xinfei Fan, Yuanlu Xu, Yanming Liu. (2023) Efficient sulfamethoxazole degradation via boosting nonradical-based peroxymonosulfate activation by biochar supported Co-Ni bimetal oxide. Journal of Environmental Chemical Engineering, 11 (110903). [PMID:] [10.1016/j.jece.2023.110903] |
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20. Nethrue Pramuditha Mendis, Jiatao Li, Richard Lakerveld. (2023) Integrated Selection of Coformers, Solvents, and Operating Conditions for Optimal Process and Product Performance of Pharmaceutical Cocrystals. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 62 (33): (13081–13095). [PMID:] [10.1021/acs.iecr.3c02168] |
21. Zhipeng Luo, Yao Xu, Diyong Tang, Li Lu, Yuanfang Li, Mengmeng Zhang, Jie Sun. (2023) Electron-transfer based selective oxidation of organic pollutants via N-doped biochar activated peroxydisulfate: Important role of oxidation potential. SEPARATION AND PURIFICATION TECHNOLOGY, 326 (124769). [PMID:] [10.1016/j.seppur.2023.124769] |
22. Sen Hu, Yuning Jiang, Jiaying Cao, Qiangting Zheng, Yiping Wu, Xiaoyu Guo, Ye Ying, Xinling Liu, Ying Wen, Haifeng Yang. (2023) Gold nanoparticles decorated MoS2 nanosheets for sensing and degradation of carbamazepine in environmental wastewater. Environmental Technology & Innovation, 32 (103302). [PMID:] [10.1016/j.eti.2023.103302] |
23. Meiling Ping, Wenchao Lv, Chen Yang, Qian Chen, Zongwen Wang, Fengfu Fu. (2023) A Paper-Based Multicolor Colorimetric Aptasensor for the Visual Determination of Multiple Sulfonamides Based on Aptamer-Functionalized Magnetic Beads and NADH–Ascorbic Acid-Mediated Gold Nanobipyramids. Chemosensors, 11 (7): (386). [PMID:] [10.3390/chemosensors11070386] |
24. Yuanyuan Fu, Zhentao Li, Changjun Hu, Qiaoyan Li, Zilin Chen. (2023) In-situ immobilization of covalent organic frameworks as stationary phase for capillary electrochromatography. JOURNAL OF CHROMATOGRAPHY A, 1705 (464205). [PMID:37442070] [10.1016/j.chroma.2023.464205] |
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