Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C169970-10mg | 10mg | In stock | $71.90 | |
C169970-50mg | 50mg | In stock | $247.90 | |
C169970-250mg | 250mg | In stock | $1,116.90 | |
C169970-1g | 1g | In stock | $4,017.90 |
Potent mitochondrial oxidative phosphorylation uncoupler
Synonyms | Mesoxalonitrile, (p-(trifluoromethoxy)phenyl)hydrazone | SR-01000645014-2 | [4-(Trifluoromethoxy)phenylhydrazono]malononitrile | Carbonyl cyanide, 4-(trifluoromethoxy)phenylhydrazone | AKOS004121079 | C74911 | Carbonyl cyanide 4-trifluoromethoxyphenylhydr |
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Specifications & Purity | ≥98%(TLC) |
Biochemical and Physiological Mechanisms | Potent mitochondrial oxidative phosphorylation uncoupler (IC 50 = 20 nM). Disrupts ATP synthesis by transporting protons across mitochondrial inner membranes. Depolarises mitochondrial membrane potential. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
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IUPAC Name | 2-[[4-(trifluoromethoxy)phenyl]hydrazinylidene]propanedinitrile |
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INCHI | InChI=1S/C10H5F3N4O/c11-10(12,13)18-9-3-1-7(2-4-9)16-17-8(5-14)6-15/h1-4,16H |
InChi Key | BMZRVOVNUMQTIN-UHFFFAOYSA-N |
Canonical SMILES | C1=CC(=CC=C1NN=C(C#N)C#N)OC(F)(F)F |
Isomeric SMILES | C1=CC(=CC=C1NN=C(C#N)C#N)OC(F)(F)F |
WGK Germany | 3 |
RTECS | FG5775000 |
PubChem CID | 3330 |
Molecular Weight | 254.17 |
Beilstein | 664446 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
J2114190 | Certificate of Analysis | Jul 05, 2024 | C169970 |
H2211080 | Certificate of Analysis | Jun 18, 2022 | C169970 |
H2211086 | Certificate of Analysis | Jun 18, 2022 | C169970 |
H2211087 | Certificate of Analysis | Jun 18, 2022 | C169970 |
H2211104 | Certificate of Analysis | Jun 18, 2022 | C169970 |
K2315063 | Certificate of Analysis | Jun 18, 2022 | C169970 |
Solubility | 95% ethanol: soluble |
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Melt Point(°C) | 156 °C(dec.) |
Pictogram(s) | GHS06, GHS07 |
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Signal | Danger |
Hazard Statements | H301:Toxic if swallowed H413:May cause long lasting harmful effects to aquatic life H317:May cause an allergic skin reaction |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. |
WGK Germany | 3 |
RTECS | FG5775000 |
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