Carmofur - >98.0%(HPLC), high purity , CAS No.61422-45-5

Item Number

C153374

Grouped product items
SKU	Size	Availability	Price
C153374-250mg	250mg	In stock	$12.90
C153374-1g	1g	In stock	$39.90
C153374-5g	5g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$150.90

Potent acid ceramidase inhibitor. Antimetabolite agent.

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Basic Description

Synonyms	carmofur\|61422-45-5\|HCFU\|Mifurol\|1-Hexylcarbamoyl-5-fluorouracil\|5-fluoro-N-hexyl-2,4-dioxo-3,4-dihydropyrimidine-1(2H)-carboxamide\|1(2H)-Pyrimidinecarboxamide, 5-fluoro-N-hexyl-3,4-dihydro-2,4-dioxo-\|NSC-758963\|5-fluoro-N-hexyl-2,4-dioxopyrimidine-1-carb
Specifications & Purity	>98.0%(HPLC)
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Product Description	Product Application: Carmofur has been used as an inhibitor of acid ceramidase to study its effects on glucosylsphingosine (GlcSph) production in human embryonic kidney 293T (HEK293T) cells. It has also been used as an inhibitor of acid ceramidase to study its effects on acid‐mediated hydrolysis of ceramide which kicks-in consumption and the generation of sphingosine.

Names and Identifiers

IUPAC Name	5-fluoro-N-hexyl-2,4-dioxopyrimidine-1-carboxamide
INCHI	InChI=1S/C11H16FN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)
InChi Key	AOCCBINRVIKJHY-UHFFFAOYSA-N
Canonical SMILES	CCCCCCNC(=O)N1C=C(C(=O)NC1=O)F
Isomeric SMILES	CCCCCCNC(=O)N1C=C(C(=O)NC1=O)F
WGK Germany	3
RTECS	UV7714000
PubChem CID	2577
Molecular Weight	257.27
Reaxy-Rn	888898

Certificates

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4 results found

Lot Number	Certificate Type	Date	Item
F2313509	Certificate of Analysis	Jun 25, 2023	C153374
F2313514	Certificate of Analysis	Jun 25, 2023	C153374
F2313519	Certificate of Analysis	Jun 25, 2023	C153374
F2313532	Certificate of Analysis	Jun 25, 2023	C153374

Solubility

Insoluble in water; Soluble in Chloroform,Acetone; Slightly soluble in Methanol,Ethanol

Sensitivity

Heat Sensitive

Melt Point(°C)

112 °C(dec.)

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08
Signal	Danger
Hazard Statements	H301:Toxic if swallowed H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P318:if exposed or concerned, get medical advice.
WGK Germany	3
RTECS	UV7714000
Reaxy-Rn	888898
Merck Index	1844

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Basic Description