Carmustine - ≥98%, high purity , RNA inhibitor, CAS No.154-93-8, RNA inhibitor

Item Number

C132260

• Synonyms: FIVB | Spectrum4_000888 | SK-27702 | Bis(chloroethyl)nitrosourea | Bis-N,N'-(chloroethyl)nitrosourea | CCRIS 810 | SRI-1720 | BCNU [Chloroethyl nitrosoureas] | Carmustin | CARMUSTINE [USP-RS] | DTI-015 | Carmustine (98%) | BiCNU (TN) | CARMUSTINE [INN] |
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Carmustine is a member of the antineoplastic nitrosourea compounds. Carmustine can perform both alkylating and carabamoylating action and owes part of its cytotoxicity to its demonstrated ability to produce interstrand DNA cross linking. In addition, this
• Storage Temp: Store at -20°C,Argon charged
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: RNA inhibitor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Carmustine is a cell-cycle phase nonspecific alkylating antineoplastic agent
A DNA alkylating and cross-linking agent used in the treatment of brain tumors and various other malignant neoplasms

General description：

Carmustine is a mustard gas related β-chloro-nitrosourea compound, which is used in chemotherapy. It inhibits DNA replication and DNA transcription.

Application：

Carmustine has been used to select transduced cells expressing MGMTP140K, a foamy virus vector. It has also been used in fluorescence-activated cell sorting (FACS) assay, to test the response of cell lines to carmustine.