Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C117958-25mg | 25mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $441.90 | |
C117958-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,590.90 |
Polyphenol compound with various biological actions
Synonyms | Carnosic acid, primary pharmaceutical reference standard | HY-N0644 | CARNOSIC ACID (CONSTITUENT OF ROSEMARY) [DSC] | BCP0726000155 | (4aR,10aS)-5,6-dihydroxy-1,1-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-4a-carboxylic acid | Carnosic ac |
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Specifications & Purity | analytical standard, ≥97% |
Biochemical and Physiological Mechanisms | Found in Rosmarinus officinalis . Displays antioxidative, anticancer, antiangiogenic, anti-inflammatory, and hepatoprotective and neuroprotective effects. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | analytical standard |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Carnosic acid is a diterpenoid that acts as an effective lipid peroxidation inhibitor in liposomal and microsomal environments, with antioxidant properties. Carnosic acid has been reported to scavenge peroxyl radicals, H2O2, reduce cytochrome C, and act more potently than Propyl gallate.Studies indicate that Carnosic acid protects red cells from oxidative hemolysis and in the xanthine/xanthine oxidase system inhibits superoxide anion production. In addition, data suggests that Carnosic acid activates PPARγ (peroxisome proliferator activated receptor γ). |
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IUPAC Name | (4aR,10aS)-5,6-dihydroxy-1,1-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-4a-carboxylic acid |
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INCHI | InChI=1S/C20H28O4/c1-11(2)13-10-12-6-7-14-19(3,4)8-5-9-20(14,18(23)24)15(12)17(22)16(13)21/h10-11,14,21-22H,5-9H2,1-4H3,(H,23,24)/t14-,20+/m0/s1 |
InChi Key | QRYRORQUOLYVBU-VBKZILBWSA-N |
Canonical SMILES | CC(C)C1=C(C(=C2C(=C1)CCC3C2(CCCC3(C)C)C(=O)O)O)O |
Isomeric SMILES | CC(C)C1=C(C(=C2C(=C1)CC[C@@H]3[C@@]2(CCCC3(C)C)C(=O)O)O)O |
WGK Germany | 3 |
PubChem CID | 65126 |
Molecular Weight | 332.43 |
Beilstein | 2707918 |
Reaxy-Rn | 2707918 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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L2129116 | Certificate of Analysis | Oct 07, 2023 | C117958 |
L2129118 | Certificate of Analysis | Oct 07, 2023 | C117958 |
K2113415 | Certificate of Analysis | Aug 04, 2023 | C117958 |
D1918138 | Certificate of Analysis | Nov 11, 2022 | C117958 |
H2020088 | Certificate of Analysis | Jun 17, 2022 | C117958 |
Sensitivity | light sensitive |
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Specific Rotation[α] | 184 ° (C=1, MeOH) |
Melt Point(°C) | 190°C |
WGK Germany | 3 |
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Reaxy-Rn | 2707918 |
1. Xie Lixia, Li Zhineng, Li Haitao, Sun Jiayu, Liu Xueying, Tang Jianxin, Lin Xizhu, Xu Laijun, Zhu Yuefang, Liu Zhi, Wang Tong. (2023) Fast Quantitative Determination of Principal Phenolic Anti-oxidants in Rosemary Using Ultrasound-Assisted Extraction and Chemometrics-Enhanced HPLC–DAD Method. Food Analytical Methods, 16 (2): (386-400). [PMID:] [10.1007/s12161-022-02421-0] |
2. Yusong Jin, Yunhui Zhang, Dongmei Liu, Dewen Liu, Chunying Zhang, Huijuan Qi, Huiyan Gu, Lei Yang, Zhiqiang Zhou. (2019) Efficient Homogenization-Ultrasound-Assisted Extraction of Anthocyanins and Flavonols from Bog Bilberry (Vaccinium uliginosum L.) Marc with Carnosic Acid as an Antioxidant Additive. MOLECULES, 24 (14): (2537). [PMID:31336730] [10.3390/molecules24142537] |
1. Xie Lixia, Li Zhineng, Li Haitao, Sun Jiayu, Liu Xueying, Tang Jianxin, Lin Xizhu, Xu Laijun, Zhu Yuefang, Liu Zhi, Wang Tong. (2023) Fast Quantitative Determination of Principal Phenolic Anti-oxidants in Rosemary Using Ultrasound-Assisted Extraction and Chemometrics-Enhanced HPLC–DAD Method. Food Analytical Methods, 16 (2): (386-400). [PMID:] [10.1007/s12161-022-02421-0] |
2. Yusong Jin, Yunhui Zhang, Dongmei Liu, Dewen Liu, Chunying Zhang, Huijuan Qi, Huiyan Gu, Lei Yang, Zhiqiang Zhou. (2019) Efficient Homogenization-Ultrasound-Assisted Extraction of Anthocyanins and Flavonols from Bog Bilberry (Vaccinium uliginosum L.) Marc with Carnosic Acid as an Antioxidant Additive. MOLECULES, 24 (14): (2537). [PMID:31336730] [10.3390/molecules24142537] |