Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C153919-1g | 1g | In stock | $68.90 | |
C153919-5g | 5g | In stock | $232.90 | |
C153919-25g | 25g | In stock | $1,047.90 | |
C153919-100g | 100g | In stock | $3,770.90 |
Selective COX-2 inhibitor. NSAID.
Synonyms | (S)-alpha-Methyl-6-chloro-9H-carbazole-2-acetic acid | 9H-Carbazole-2-acetic acid, 6-chloro-.alpha.-methyl- | Rimadyl Chewable Tablets | SPECTRUM1502006 | 6-Chloro-alpha-methyl-9H-carbazole-2-acetic acid | HMS2234P15 | Rimadyl Caplets | 5-22-03-00391 (Bei |
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Specifications & Purity | Moligand™, ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that has been found to have antimicrobial activity. Carprofen is primarily used as a veterinary analgesic and anti-inflammatory for arthritis and pain. Its anti-inflammatory activity is due to cy |
Shipped In | Normal |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Cyclooxygenase-2 inhibitor |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Carprofen inhibits canine COX2 with IC50 of 30 nM. |
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IUPAC Name | 2-(6-chloro-9H-carbazol-2-yl)propanoic acid |
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INCHI | InChI=1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19) |
InChi Key | PUXBGTOOZJQSKH-UHFFFAOYSA-N |
Canonical SMILES | CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)O |
Isomeric SMILES | CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)O |
RTECS | FE3180000 |
PubChem CID | 2581 |
Molecular Weight | 273.72 |
DrugBank Ligand | DB00821 |
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PubChem CID | 2581 |
CAS Registry No. | 53716-49-7 |
ChEMBL Ligand | CHEMBL1316 |
Wikipedia | Carprofen |
DrugCentral Ligand | 518 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
C1925141 | Certificate of Analysis | Jan 14, 2023 | C153919 |
F2309086 | Certificate of Analysis | Aug 05, 2022 | C153919 |
F2309087 | Certificate of Analysis | Aug 05, 2022 | C153919 |
J2228291 | Certificate of Analysis | Aug 05, 2022 | C153919 |
J2228374 | Certificate of Analysis | Aug 05, 2022 | C153919 |
J2228376 | Certificate of Analysis | Aug 05, 2022 | C153919 |
J2228377 | Certificate of Analysis | Aug 05, 2022 | C153919 |
Solubility | Soluble in Methanol |
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Melt Point(°C) | 200 °C |
Pictogram(s) | GHS06 |
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Signal | Danger |
Hazard Statements | H301:Toxic if swallowed |
Precautionary Statements | P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. |
RTECS | FE3180000 |
Merck Index | 1862 |
1. Lijuan Zang, Man He, Zhekuan Wu, Beibei Chen, Bin Hu. (2021) Imine-linked covalent organic frameworks coated stir bar sorptive extraction of non-steroidal anti-inflammatory drugs from environmental water followed by high performance liquid chromatography-ultraviolet detection. JOURNAL OF CHROMATOGRAPHY A, 1659 (462647). [PMID:34731758] |
1. Lijuan Zang, Man He, Zhekuan Wu, Beibei Chen, Bin Hu. (2021) Imine-linked covalent organic frameworks coated stir bar sorptive extraction of non-steroidal anti-inflammatory drugs from environmental water followed by high performance liquid chromatography-ultraviolet detection. JOURNAL OF CHROMATOGRAPHY A, 1659 (462647). [PMID:34731758] |