Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C114051-10mg | 10mg | In stock | $206.90 | |
C114051-20mg | 20mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $309.90 | |
C114051-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,236.90 |
Natural flavonoid compound
Synonyms | (+)-(2R:3S)-5,7,3',4'-Tetrahydroxyflavan-3-ol | (+)-CATECHIN (USP-RS) | (+/-)-Catechin | 2-(3,4-Dihydroxyphenyl)chromane-3,5,7-triol | DL-Catechine | Prestwick1_000817 | CATECHIN, DL- | Catechinate | (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene |
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Specifications & Purity | analytical standard, ≥97% |
Biochemical and Physiological Mechanisms | Natural flavonoid compound. Various pharmacological activities including antioxident and anticancer effects. Induces apoptosis and promotes cell growth arrest via a number of intracellular pathways. Active in vitro and in vivo . |
Storage Temp | Store at 2-8°C,Protected from light |
Shipped In | Wet ice |
Grade | analytical standard |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol |
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INCHI | InChI=1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15+/m0/s1 |
InChi Key | PFTAWBLQPZVEMU-DZGCQCFKSA-N |
Canonical SMILES | C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O |
Isomeric SMILES | C1[C@@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O |
WGK Germany | 3 |
Alternate CAS | 225937-10-0 |
PubChem CID | 9064 |
Molecular Weight | 290.27 |
Beilstein | 3595244 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
E2413228 | Certificate of Analysis | May 07, 2024 | C114051 |
E2413237 | Certificate of Analysis | May 07, 2024 | C114051 |
E2413250 | Certificate of Analysis | May 07, 2024 | C114051 |
E2413251 | Certificate of Analysis | May 07, 2024 | C114051 |
H2321671 | Certificate of Analysis | Aug 10, 2023 | C114051 |
H2321670 | Certificate of Analysis | Aug 10, 2023 | C114051 |
H2321669 | Certificate of Analysis | Aug 10, 2023 | C114051 |
F2116098 | Certificate of Analysis | Mar 14, 2023 | C114051 |
F2116099 | Certificate of Analysis | Mar 14, 2023 | C114051 |
D23141244 | Certificate of Analysis | Feb 16, 2023 | C114051 |
D23141245 | Certificate of Analysis | Feb 16, 2023 | C114051 |
D23141247 | Certificate of Analysis | Feb 16, 2023 | C114051 |
G2326082 | Certificate of Analysis | Feb 16, 2023 | C114051 |
I1523098 | Certificate of Analysis | Jan 05, 2023 | C114051 |
B1707017 | Certificate of Analysis | Aug 05, 2022 | C114051 |
B2218371 | Certificate of Analysis | Feb 09, 2022 | C114051 |
A2303430 | Certificate of Analysis | Feb 09, 2022 | C114051 |
Sensitivity | Light sensitive |
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Specific Rotation[α] | 15.5 ° (C=5, Acetone) |
Melt Point(°C) | 175-177°C |
Pictogram(s) | GHS07 |
---|---|
Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
Merck Index | 1902 |
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1. Edidiong Joseph Bassey, Jun-Hu Cheng, Da-Wen Sun. (2024) Comparative elucidation of bioactive and antioxidant properties of red dragon fruit peel as affected by electromagnetic and conventional drying approaches. FOOD CHEMISTRY, 439 (138118). [PMID:38109834] |
2. Mengyang Hou, Chengyuan Lin, Yanhua Ma, Jingchun Shi, Jie Liu, Lin Zhu, Zhaoxiang Bian. (2024) One-step enrichment of phenolics from Chaenomeles speciosa (Sweet) Nakai fruit using macroporous resin: Adsorption/desorption characteristics, process optimization and UPLC-QqQ-MS/MS-based quantification. FOOD CHEMISTRY, 439 (22): (138085). [PMID:38039612] |
3. Shuai-Nan Zhang, Qi Liu, Xu-Zhao Li, Wu-De Yang, Ying Zhou. (2024) Liver protein and metabolite biolabels reveal hepatoprotective effects and active compounds of Eucommiae folium: Exploration of new application of herb based on multi-omics and bioinformatics. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 239 (19): (115870). [PMID:38008044] |
4. Jingjing Sun, Wei Chen, Zheng Zhou, Xin Chen, You Zuo, Jiaqian He, Hairong Liu. (2023) Tanshinone IIA Facilitates Efficient Cartilage Regeneration under Inflammatory Factors Caused Stress via Upregulating LncRNA NEAT1_2. Biomedicines, 11 (12): (3291). [PMID:38137512] |
5. Zhang Shuai-nan, Liu Qi, Li Xu-zhao, Yang Wu-de, Zhou Ying. (2023) Cardioprotection of Eucommiae Folium: the extract and pharmaceutically active compounds attenuate hyperglycemia, mitochondrial dysfunction, calcium dyshomeostasis, insulin resistance, and oxidative stress in diabetic cardiomyopathy db/db mice. JOURNAL OF PHARMACY AND PHARMACOLOGY, 75 (12): (1509-1520). [PMID:37889854] |
6. Yating Guo, Yili Shen, Boya Hu, Huichun Ye, Haowei Guo, Qiang Chu, Ping Chen. (2023) Decoding the Chemical Signatures and Sensory Profiles of Enshi Yulu: Insights from Diverse Tea Cultivars. Plants-Basel, 12 (21): (3707). [PMID:37960063] |
7. Liu Xinru, Ma Qianwei, Sun Yongjun, Ju Wenming, Kumrungsee Thanutchaporn, Zhou Zhongkai, Wang Lijuan, Cao Ruge. (2023) Effects of Processings and Complexation on Solubility, Antioxidant and Antibacterial Properties of Buckwheat Polyphenols. Food and Bioprocess Technology, (8): (1-13). [PMID:18063578] |
8. Hangwei Wang, Zhanren Liu, Shaojie Liu, Ruoru Yang, Yifei Wang, Yiying Gu, Min Wu, Ruihua Dong, Bo Chen. (2023) The Therapeutic Effect of Catechin on Nephrolithiasis Induced by Co-Exposure to Melamine and Cyanuric Acid in Sprague–Dawley Rats. Toxics, 11 (9): (799). [PMID:37755809] |
9. Zhiyu Sun, Yongbin Zhou, Wenxu Zhu, You Yin. (2023) Assessment of the Fruit Chemical Characteristics and Antioxidant Activity of Different Mulberry Cultivars (Morus spp.) in Semi-Arid, Sandy Regions of China. Foods, 12 (18): (3495). [PMID:37761204] |
10. Wen Xia, Bingbing Song, Tong Li, Rui Hai Liu. (2023) Phytochemical profiles, antioxidant activities, and synergistic antiproliferative effects of blueberry and apple peel extracts. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, (15): [PMID:37658664] |
11. Dongsheng Hu, Xiaogang Liu, Yuyue Qin, Jiatong Yan, Rongmei Li, Qiliang Yang. (2023) The impact of different drying methods on the physical properties, bioactive components, antioxidant capacity, volatile components and industrial application of coffee peel. Food Chemistry-X, 19 (100807). [PMID:37780243] |
12. Su Zhou, Jiaying Yang, Yani Pan, Xinyu Feng, Hao Hu, Shicheng Ma, Cansong Ou, Fangyuan Fan, Shuying Gong, Yuefei Wang, Ping Chen, Qiang Chu. (2023) Pu’ er raw tea extract alleviates DSS-induced colitis in mice by restoring intestinal barrier function and maintaining gut microbiota homeostasis. Food Bioscience, 53 (102750). [PMID:] |
13. Lei He, Qian Hu, Liyang Wei, Xuliyang Ge, Ning Yu, Ying Chen. (2023) Unravelling dynamic changes in non-volatile and volatile metabolites of pulses during soaking: An integrated metabolomics approach. FOOD CHEMISTRY, 422 (136231). [PMID:37141754] |
14. Fanghua Guo, Li Peng, Hua Xiong, Rong Tsao, Hua Zhang, Li Jiang, Yong Sun. (2023) Bioaccessibility and transport of lentil hull polyphenols in vitro, and their bioavailability and metabolism in rats. FOOD RESEARCH INTERNATIONAL, 167 (112634). [PMID:37087206] |
15. Huiqun Fan, Mingshun Chen, Taotao Dai, Lizhen Deng, Chengmei Liu, Wei Zhou, Jun Chen. (2023) Phenolic compounds profile of Amomum tsaoko Crevost et Lemaire and their antioxidant and hypoglycemic potential. Food Bioscience, 52 (102508). [PMID:] |
16. Ruiyi Fan, Congyi Zhu, Diyang Qiu, Genlin Mao, Bernd Mueller-Roeber, Jiwu Zeng. (2023) Integrated transcriptomic and metabolomic analyses reveal key genes controlling flavonoid biosynthesis in Citrus grandis ‘Tomentosa’ fruits. PLANT PHYSIOLOGY AND BIOCHEMISTRY, 196 (210). [PMID:36724705] |
17. Tong Zhang, Yuan Chen, Tao Wang, Chang Liu, Dan He, Bin Liu, Yuanyuan Liu. (2023) Efficient removal of petroleum hydrocarbons from soil by percarbonate with catechin-promoted Fe(III)/Fe(II) redox cycling: Activation of ferrous and roles of ·OH and ·CO3-. JOURNAL OF HAZARDOUS MATERIALS, 448 (130875). [PMID:36731317] |
18. Jianhui Zhu, Jingyang Yu, Bingjie Zhang, Changsheng Li, Jianli Wang, Jiawen Ji, Desheng Liu, Rumin Gao, Jianzhang Li, Yongqiang Ma. (2023) Hydrophobic-action-driven removal of six organophosphorus pesticides from tea infusion by modified carbonized bacterial cellulose. FOOD CHEMISTRY, 412 (135546). [PMID:36716625] |
19. Lixia Yang, Zhendong Lu, Jian Lu, Dianhui Wu. (2022) Evaluation of the antioxidant characteristics of craft beer with green tea. JOURNAL OF FOOD SCIENCE, 88 (2): (625-637). [PMID:36576119] |
20. Xiaoman Li, Ruobing Qiao, Xuyang Jiu, Minglei Tian. (2022) Solid Phase Extraction of (+)-Catechin from Cocoa Shell Waste Using Dual Ionic Liquid@ZIF8 Covered Silica. Separations, 9 (12): (441). [PMID:] |
21. Shuwen Li, Zhiguo Wang, Siyi Chen, Jialin Gu, Yanping Ma, Jiangang Jiang, Rui Zhang, Dan Zhang, Yiping Wang, He Wang. (2023) Ratiometric fluorescence sensing based on rare-earth upconversion nanoparticles for the rapid identification of antioxidant capacity. NEW JOURNAL OF CHEMISTRY, 47 (4): (2079-2085). [PMID:] |
22. Shi Xia, Fang Jiaxing, Du Huicong, Zhang Sufang, Liu Fu, Zhang Zhen, Kong Xiangbo. (2022) Performance of two Ips bark beetles and their associated pathogenic fungi on hosts reflects a species-specific association in the beetle-fungus complex. Frontiers in Plant Science, 13 [PMID:36483952] |
23. Min Chen, Yifei Xiao, Fugui Zhang, Jianhao Du, Li Zhang, Yifang Li, Danyi Lu, Zhigang Wang, Baojian Wu. (2022) Tangeretin prevents cognitive deficit in delirium through activating RORα/γ-E4BP4 axis in mice. BIOCHEMICAL PHARMACOLOGY, 205 (115286). [PMID:36216079] |
24. Fanghua Guo, Li Peng, Hua Xiong, Jiaqi Wang, Rong Tsao, Xin Peng, Li Jiang, Yong Sun. (2022) Free and Bound Phenolics of Laird Lentil (Lens culinaris) Hulls and the Anti-inflammatory Activity of their Digestive Products via Crosstalk between NF-κB and Keap1-Nrf2 Signaling Pathways in HT-29 Cells. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70 (41): (13251–13263). [PMID:36196880] |
25. Hui Jiang, Fei Wu, Xi Jiang, Yun-Feng Pu, Li-Rong Shen, Cui-Yun Wu, Hong-Jin Bai. (2022) Antioxidative, cytoprotective and whitening activities of fragrant pear fruits at different growth stages. Frontiers in Nutrition, 9 (1020855). [PMID:36245497] |
26. Jing Feng, Gang Lang, Tingting Li, Jing Zhang, Jun Zhao, Wei Li, Weiqing Yang, Zhenju Jiang. (2022) Enhanced electrochemical detection performance of C-Cr2O3 towards glucose and hydrazine by assembling Ni-MPN coating. APPLIED SURFACE SCIENCE, 604 (154548). [PMID:] |
27. Zhi-Ang Liu, Ya-Nan Zuo, Yinghui Xia, Jing Sun, Shuyun Zhu. (2022) Enhanced detection of ascorbic acid with cascaded fluorescence recovery of a dual-nanoquencher system. Analytical Methods, 14 (37): (3632-3637). [PMID:36052693] |
28. Jie Hu, Rui Chen, Zhenglin Li, Fenzan Wu, Yanhong Yang, Yu Yang, Xiaokun Li, Jian Xiao. (2022) Polyphenol-Coordinated Supramolecular Hydrogel as a Promising “One-Stop-Shop” Strategy for Acute Infected Wound Treatment. Applied Materials Today, 29 (101586). [PMID:] |
29. Yao Fan, Siying Che, Lei Zhang, Chunsong Zhou, Haiyan Fu, Yuanbin She. (2022) Dual channel sensor array based on ZnCdSe QDs – KMnO4: An effective tool for analysis of catechins and green teas. FOOD RESEARCH INTERNATIONAL, 160 (111734). [PMID:36076421] |
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