Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C131962-1mg | 1mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $136.90 | |
C131962-5mg | 5mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $301.90 | |
C131962-10mg | 10mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $486.90 | |
C131962-25mg | 25mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,095.90 |
Synonyms | (?)-Catechin gallate | (-)-Catechin gallate | C22H18O10 | S00277 | (-)-Catechin gallate(CG) | (2S,3R)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxychroman-3-yl 3,4,5-trihydroxybenzoate | AC-34201 | ent-Catechin 3-O-gallate | Benzoic acid, 3,4,5-trihydroxy-, 2-(3, |
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Specifications & Purity | ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | Antioxidant constituent of green tea. At μM concentrations, it inhibits VEGF-induced tyrosine phosphorylation. It also inhibits aromatase activity, an enzyme that converts androgens to estrogen and is thought to play a role in the etiology of breast cance |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Product Description | (-) -catechin gallate is a microcomponent of green tea Catechin, which can inhibit the activities of COX-1 and COX-2. It inhibits human Beta-Secretase, and chloroquine-sensitive Plasmodium falciparum NF54 and chloroquine-resistant Plasmodium falciparum K1 have antiplasmodium activity. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | [(2S,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate |
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INCHI | InChI=1S/C22H18O10/c23-11-6-14(25)12-8-19(32-22(30)10-4-16(27)20(29)17(28)5-10)21(31-18(12)7-11)9-1-2-13(24)15(26)3-9/h1-7,19,21,23-29H,8H2/t19-,21+/m1/s1 |
InChi Key | LSHVYAFMTMFKBA-CTNGQTDRSA-N |
Canonical SMILES | C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O |
Isomeric SMILES | C1[C@H]([C@@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O |
WGK Germany | 3 |
PubChem CID | 6419835 |
Molecular Weight | 442.37 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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Certificate of Analysis | Oct 13, 2023 | C131962 | |
Certificate of Analysis | Oct 13, 2023 | C131962 | |
Certificate of Analysis | Sep 18, 2023 | C131962 | |
Certificate of Analysis | Sep 18, 2023 | C131962 | |
Certificate of Analysis | Sep 18, 2023 | C131962 | |
Certificate of Analysis | May 31, 2023 | C131962 | |
Certificate of Analysis | May 31, 2023 | C131962 | |
Certificate of Analysis | May 31, 2023 | C131962 | |
Certificate of Analysis | May 31, 2023 | C131962 |
Solubility | DMSO : 100 mg/mL (226.06 mM) |
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Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
1. Yating Guo, Yili Shen, Boya Hu, Huichun Ye, Haowei Guo, Qiang Chu, Ping Chen. (2023) Decoding the Chemical Signatures and Sensory Profiles of Enshi Yulu: Insights from Diverse Tea Cultivars. Plants-Basel, 12 (21): (3707). [PMID:37960063] |
2. Su Zhou, Jiaying Yang, Yani Pan, Xinyu Feng, Hao Hu, Shicheng Ma, Cansong Ou, Fangyuan Fan, Shuying Gong, Yuefei Wang, Ping Chen, Qiang Chu. (2023) Pu’ er raw tea extract alleviates DSS-induced colitis in mice by restoring intestinal barrier function and maintaining gut microbiota homeostasis. Food Bioscience, 53 (102750). [PMID:] |
3. Wanglong Zhang, Yu Dai, Fan Xia, Xiaojin Zhang. (2023) Interfacial Molecular Lock: A Universal Strategy for Hydrogel Adhesion. ACS Applied Polymer Materials, 5 (1): (1037–1045). [PMID:] |
4. Yu-Meng Zhu, Jun-Jie Dong, Jing Jin, Jin-Hua Liu, Xin-Qiang Zheng, Jian-Liang Lu, Yue-Rong Liang, Jian-Hui Ye. (2021) Roasting process shaping the chemical profile of roasted green tea and the association with aroma features. FOOD CHEMISTRY, 353 (129428). [PMID:33714119] |
5. Dandan Qin, Qiushuang Wang, Hongjian Li, Xiaohui Jiang, Kaixing Fang, Qing Wang, Bo Li, Chendong Pan, Hualing Wu. (2020) Identification of key metabolites based on non-targeted metabolomics and chemometrics analyses provides insights into bitterness in Kucha [Camellia kucha (Chang et Wang) Chang]. FOOD RESEARCH INTERNATIONAL, 138 (109789). [PMID:33288175] |
6. Meng Shi, Ying Nie, Xin-Qiang Zheng, Jian-Liang Lu, Yue-Rong Liang, Jian-Hui Ye. (2016) Ultraviolet B (UVB) Photosensitivities of Tea Catechins and the Relevant Chemical Conversions. MOLECULES, 21 (10): (1345). [PMID:27735869] |
7. Fang-Yuan Fan, Meng Shi, Ying Nie, Yue Zhao, Jian-Hui Ye, Yue-Rong Liang. (2016) Differential behaviors of tea catechins under thermal processing: Formation of non-enzymatic oligomers. FOOD CHEMISTRY, 196 (347). [PMID:26593500] |
1. Yating Guo, Yili Shen, Boya Hu, Huichun Ye, Haowei Guo, Qiang Chu, Ping Chen. (2023) Decoding the Chemical Signatures and Sensory Profiles of Enshi Yulu: Insights from Diverse Tea Cultivars. Plants-Basel, 12 (21): (3707). [PMID:37960063] |
2. Su Zhou, Jiaying Yang, Yani Pan, Xinyu Feng, Hao Hu, Shicheng Ma, Cansong Ou, Fangyuan Fan, Shuying Gong, Yuefei Wang, Ping Chen, Qiang Chu. (2023) Pu’ er raw tea extract alleviates DSS-induced colitis in mice by restoring intestinal barrier function and maintaining gut microbiota homeostasis. Food Bioscience, 53 (102750). [PMID:] |
3. Wanglong Zhang, Yu Dai, Fan Xia, Xiaojin Zhang. (2023) Interfacial Molecular Lock: A Universal Strategy for Hydrogel Adhesion. ACS Applied Polymer Materials, 5 (1): (1037–1045). [PMID:] |
4. Yu-Meng Zhu, Jun-Jie Dong, Jing Jin, Jin-Hua Liu, Xin-Qiang Zheng, Jian-Liang Lu, Yue-Rong Liang, Jian-Hui Ye. (2021) Roasting process shaping the chemical profile of roasted green tea and the association with aroma features. FOOD CHEMISTRY, 353 (129428). [PMID:33714119] |
5. Dandan Qin, Qiushuang Wang, Hongjian Li, Xiaohui Jiang, Kaixing Fang, Qing Wang, Bo Li, Chendong Pan, Hualing Wu. (2020) Identification of key metabolites based on non-targeted metabolomics and chemometrics analyses provides insights into bitterness in Kucha [Camellia kucha (Chang et Wang) Chang]. FOOD RESEARCH INTERNATIONAL, 138 (109789). [PMID:33288175] |
6. Meng Shi, Ying Nie, Xin-Qiang Zheng, Jian-Liang Lu, Yue-Rong Liang, Jian-Hui Ye. (2016) Ultraviolet B (UVB) Photosensitivities of Tea Catechins and the Relevant Chemical Conversions. MOLECULES, 21 (10): (1345). [PMID:27735869] |
7. Fang-Yuan Fan, Meng Shi, Ying Nie, Yue Zhao, Jian-Hui Ye, Yue-Rong Liang. (2016) Differential behaviors of tea catechins under thermal processing: Formation of non-enzymatic oligomers. FOOD CHEMISTRY, 196 (347). [PMID:26593500] |