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(+)-Catechin hydrate - ≥96.0% (sum of enantiomers, HPLC), high purity , CAS No.225937-10-0

6 Citations
  • ≥96%(HPLC)
  • sum of enantiomers
Item Number
C464218
Grouped product items
SKUSizeAvailabilityPrice Qty
C464218-1g
1g
In stock
$133.90
C464218-10g
10g
In stock
$387.90
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Bulk Order  SDS  DATASHEET

Basic Description

Synonyms(+)-Catechin Hydrate | Catechin hydrate | 225937-10-0 | (+)-catechin monohydrate | 88191-48-4 | (2R,3S)-2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol hydrate | (+)-Cyanidol-3 | CHEBI:58994 | (2R-trans)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol monohydr
Specifications & Purity≥96%(HPLC), sum of enantiomers
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

Catechin hydrate is a polyphenolic flavonoid that exhibits antioxidant properties. It is commonly found in green tea, grape seeds, and bark of few trees like acacia and mahogany.(+)-Catechin hydrate can be used:As an inhibitor of steel corrosion in hydrochloric acid solution.As a model compound in the study of antimicrobial activities of flavonoids onEscherichia coli.As a starting material for the synthesis of catechin glucosides of biological importance.

Associated Targets(Human)

ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLB Tchem DNA polymerase beta (23632 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GAA Tclin Lysosomal alpha-glucosidase (35701 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALPG Tchem Alkaline phosphatase placental-like (1197 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALPL Tchem Alkaline phosphatase, tissue-nonspecific isozyme (1551 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAN Tchem GTP-binding nuclear protein Ran/Importin subunit beta-1/Snurportin-1 (21853 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Iap Intestinal alkaline phosphatase (419 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
dnaB Replicative DNA helicase (15 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BCHE Cholinesterase (8742 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Large T antigen (1457 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
recA Protein RecA (2211 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol;hydrate
INCHI InChI=1S/C15H14O6.H2O/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7;/h1-5,13,15-20H,6H2;1H2/t13-,15+;/m0./s1
InChi Key OFUMQWOJBVNKLR-NQQJLSKUSA-N
Canonical SMILES C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O.O
Isomeric SMILES C1[C@@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O.O
WGK Germany 3
RTECS DJ3450000
Alternate CAS 154-23-4
PubChem CID 107957
Molecular Weight 290.27
Beilstein 3595244
Reaxy-Rn 92761

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

4 results found

Lot NumberCertificate TypeDateItem
J2310402Certificate of AnalysisSep 21, 2023 C464218
J2310403Certificate of AnalysisSep 21, 2023 C464218
J2310404Certificate of AnalysisSep 21, 2023 C464218
J2310405Certificate of AnalysisSep 21, 2023 C464218

Chemical and Physical Properties

SensitivityLoss of crystalline water during storage
Melt Point(°C)96°C(lit.)

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS DJ3450000
Reaxy-Rn 92761

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Citations of This Product

1. Zijian Liang, Pangzhen Zhang, Wen Ma, Xin-An Zeng, Zhongxiang Fang.  (2024)  Physicochemical properties, antioxidant activities and comprehensive phenolic profiles of tea-macerated Chardonnay wine and model wine.  FOOD CHEMISTRY,  436  (4): (137748).  [PMID:37862991]
2. Tong Jiang, Hong Wang, Peihua Xu, Yifan Yao, Yilong Ma, Zhaojun Wei, Xiangli Niu, Yafang Shang, Dong Zhao.  (2023)  Effect of grape seed proanthocyanidin on the structural and physicochemical properties of bread during bread fermentation stage.  Current Research in Food Science,  7  (100559).  [PMID:37600464]
3. Mao-Ling Luo, Hua Chen, Guo-Ying Chen, Shengpeng Wang, Yitao Wang, Feng-Qing Yang.  (2023)  Preparation of Alcohol Dehydrogenase–Zinc Phosphate Hybrid Nanoflowers through Biomimetic Mineralization and Its Application in the Inhibitor Screening.  MOLECULES,  28  (14): (5429).  [PMID:37513303]
4. Chengxiang Chu, Xianfeng Wang, Yuanyi Deng, Yi Ma, Chengyue Zou, Mei Yang, Huibo Luo, Danqun Huo, Changjun Hou.  (2023)  Discrimination of Chinese green tea according to tea polyphenols using fluorescence sensor array based on Tb (III) and Eu (III) doped Zr (IV) metal–organic frameworks.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  292  (122380).  [PMID:36736046]
5. Shuai Zhang, Qin Ma, Lihong Dong, Xuchao Jia, Lei Liu, Fei Huang, Guang Liu, Zhida Sun, Jianwei Chi, Mingwei Zhang, Ruifen Zhang.  (2022)  Phenolic profiles and bioactivities of different milling fractions of rice bran from black rice.  FOOD CHEMISTRY,  378  (132035).  [PMID:35042109]
6. Yirong Xia, Xintong Wang, Hechen Sun, Ximing Huang.  (2021)  Proton-coupled electron transfer of catechin in tea wine: the enhanced mechanism of anti-oxidative capacity.  RSC Advances,  11  (63): (39985-39993).  [PMID:35494161]

References

1. Phedias Diamandis,Jan Wildenhain,Ian D Clarke,Adrian G Sacher,Jeremy Graham,David S Bellows,Erick K M Ling,Ryan J Ward,Leanne G Jamieson,Mike Tyers,Peter B Dirks.  (2007-04-10)  Chemical genetics reveals a complex functional ground state of neural stem cells..  Nature chemical biology,  3  ((5)): (268-273).  [PMID:17417631]
2. Jun Liu,Jian-feng Lu,Xiao-yuan Wen,Juan Kan,Chang-hai Jin.  (2014-10-16)  Antioxidant and protective effect of inulin and catechin grafted inulin against CCl4-induced liver injury..  International journal of biological macromolecules,  72  (1479-1484).  [PMID:25316429]
3. Marlena K Sheridan,Ryan J Elias.  (2015-02-11)  Exogenous acetaldehyde as a tool for modulating wine color and astringency during fermentation..  Food chemistry,  177  (17-22).  [PMID:25660852]
4. Bradley W Bolling,Rod Taheri,Ruisong Pei,Sarah Kranz,Mo Yu,Shelley N Durocher,Mark H Brand.  (2015-05-16)  Harvest date affects aronia juice polyphenols, sugars, and antioxidant activity, but not anthocyanin stability..  Food chemistry,  187  (189-196).  [PMID:25977015]
5. Arianna Ricci,Giuseppina P Parpinello,Kenneth J Olejar,Paul A Kilmartin,Andrea Versari.  (2015-12-10)  Attenuated Total Reflection Mid-Infrared (ATR-MIR) Spectroscopy and Chemometrics for the Identification and Classification of Commercial Tannins..  Applied spectroscopy,  69  ((11)): (1243-1250).  [PMID:26647047]
6. Duckgue Lee,Daniel Hokinson,Soyoung Park,Rosalie Elvira,Fedho Kusuma,Ji-Min Lee,Miyong Yun,Seok-Geun Lee,Jaeseok Han.  (2019-12-19)  ER Stress Induces Cell Cycle Arrest at the G2/M Phase Through eIF2α Phosphorylation and GADD45α..  International journal of molecular sciences,  20  ((24)):   [PMID:31847234]
7. B T Duhart,D Zhang,J Deck,J P Freeman,C E Cerniglia.  (1999-08-24)  Biotransformation of protriptyline by filamentous fungi and yeasts..  Xenobiotica; the fate of foreign compounds in biological systems,  29  ((7)): (733-746).  [PMID:10456691]
8. M J Reis Lima,Ildikó V Tóth,António O S S Rangel.  (2008-10-31)  A new approach for the sequential injection spectrophotometric determination of the total antioxidant activity..  Talanta,  68  ((2)): (207-213).  [PMID:18970306]
9. Zijian Liang, Pangzhen Zhang, Wen Ma, Xin-An Zeng, Zhongxiang Fang.  (2024)  Physicochemical properties, antioxidant activities and comprehensive phenolic profiles of tea-macerated Chardonnay wine and model wine.  FOOD CHEMISTRY,  436  (4): (137748).  [PMID:37862991]
10. Tong Jiang, Hong Wang, Peihua Xu, Yifan Yao, Yilong Ma, Zhaojun Wei, Xiangli Niu, Yafang Shang, Dong Zhao.  (2023)  Effect of grape seed proanthocyanidin on the structural and physicochemical properties of bread during bread fermentation stage.  Current Research in Food Science,  7  (100559).  [PMID:37600464]
11. Mao-Ling Luo, Hua Chen, Guo-Ying Chen, Shengpeng Wang, Yitao Wang, Feng-Qing Yang.  (2023)  Preparation of Alcohol Dehydrogenase–Zinc Phosphate Hybrid Nanoflowers through Biomimetic Mineralization and Its Application in the Inhibitor Screening.  MOLECULES,  28  (14): (5429).  [PMID:37513303]
12. Chengxiang Chu, Xianfeng Wang, Yuanyi Deng, Yi Ma, Chengyue Zou, Mei Yang, Huibo Luo, Danqun Huo, Changjun Hou.  (2023)  Discrimination of Chinese green tea according to tea polyphenols using fluorescence sensor array based on Tb (III) and Eu (III) doped Zr (IV) metal–organic frameworks.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  292  (122380).  [PMID:36736046]
13. Shuai Zhang, Qin Ma, Lihong Dong, Xuchao Jia, Lei Liu, Fei Huang, Guang Liu, Zhida Sun, Jianwei Chi, Mingwei Zhang, Ruifen Zhang.  (2022)  Phenolic profiles and bioactivities of different milling fractions of rice bran from black rice.  FOOD CHEMISTRY,  378  (132035).  [PMID:35042109]
14. Yirong Xia, Xintong Wang, Hechen Sun, Ximing Huang.  (2021)  Proton-coupled electron transfer of catechin in tea wine: the enhanced mechanism of anti-oxidative capacity.  RSC Advances,  11  (63): (39985-39993).  [PMID:35494161]

Solution Calculators

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