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Cathepsin L/MEP Antibody - Primary antibody, specific to Cathepsin L/MEP, Rabbit IgG

  • ExactAb™
  • Validated
  • 1.0 mg/mL
Features and benefits
  • Short Overview:

    pAb; Rabbit anti Human Cathepsin L/MEP Antibody; WB, IHC; Unconjugated

  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
    Application:
  • IHC
  • WB
Item Number
Ab093200
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab093200-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab093200-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$189.90
Ab093200-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$289.90
Ab093200-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,999.90

pAb; Rabbit anti Human Cathepsin L/MEP Antibody; WB, IHC; Unconjugated

Basic Description

Product NameCathepsin L/MEP Antibody - Primary antibody, specific to Cathepsin L/MEP, Rabbit IgG
SynonymsCathepsin L antibody; cathepsin L, 1 b antibody; Cathepsin L1 antibody; Cathepsin L1 light chain antibody; CathepsinL antibody; CATL antibody; CATL1_HUMAN antibody; cb15 antibody; CTSL antibody; CTSL1 antibody; ctsl1b antibody; FLJ31037 antibody; hgg1 ant
Specifications & PurityExactAb™, Validated, 1.0 mg/mL
Host speciesRabbit
SpecificityCathepsin L/MEP
ImmunogenA synthetic peptide derived from the Internal region of human Cathepsin L.
Positive ControlWB: H460, K562 lysates. IHC: Human colon, liver tissues.
ConjugationUnconjugated
GradeExactAb™, Validated
Product Description

Rabbit anti Human Cathepsin L/MEP Antibody, Polyclonal, could be used for WB, IHC and so on.
Application:
WB: 1/500-1/2000
IHC: 1/100-1/300
Protein Function:
Important for the overall degradation of proteins in lysosomes.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodImmunogen affinity purified
FormLiquid
Concentration1.0 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20℃ long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Associated Targets

CTSL Tclin Cathepsin L1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CTSV Tchem Cathepsin L2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

1/500-1/2000

IHC

1/100-1/300

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

References

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54. Felbor, U U and 5 more authors..  (2000)  Secreted cathepsin L generates endostatin from collagen XVIII..  The EMBO journal,    (15):   [PMID:10716919]
55. Zhang, Hui H, Li, Xiao-Jun XJ, Martin, Daniel B DB and Aebersold, Ruedi R..  (2003)  Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry..  Nature biotechnology,      [PMID:12754519]
56. Goulet, Brigitte B and 7 more authors..  (2004)  A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor..  Molecular cell,    (23):   [PMID:15099520]
57. Humphray, S J SJ and 147 more authors..  (2004)  DNA sequence and analysis of human chromosome 9..  Nature,    (27):   [PMID:15164053]
58. Liu, Tao T and 6 more authors..  ()  Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry..  Journal of proteome research,      [PMID:16335952]
59. Bechtel, Stephanie S and 18 more authors..  (2007)  The full-ORF clone resource of the German cDNA Consortium..  BMC genomics,    (31):   [PMID:17974005]
60. Rosenow, Anja A and 6 more authors..  (2012)  Resveratrol-induced changes of the human adipocyte secretion profile..  Journal of proteome research,    (7):   [PMID:22905912]
61. Bian, Yangyang Y and 9 more authors..  (2014)  An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome..  Journal of proteomics,    (16):   [PMID:24275569]
62. Zhou, Nan N and 11 more authors..  (2016)  Glycopeptide Antibiotics Potently Inhibit Cathepsin L in the Late Endosome/Lysosome and Block the Entry of Ebola Virus, Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)..  The Journal of biological chemistry,    (22):   [PMID:26953343]
63. van den Bogaard, Ellen H J EHJ and 11 more authors..  (2019)  Deficiency of the human cysteine protease inhibitor cystatin M/E causes hypotrichosis and dry skin..  Genetics in medicine : official journal of the American College of Medical Genetics,      [PMID:30425301]
64. Ou, Xiuyuan and 17 more authors..  (2020)  Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV..  Nature communications,    (27):   [PMID:32221306]
65. Smieszek, Sandra P; Przychodzen, Bart P and Polymeropoulos, Mihael H..  (2020)  Amantadine disrupts lysosomal gene expression: A hypothesis for COVID19 treatment..  International journal of antimicrobial agents,      [PMID:32361028]

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