| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab093242-10μl | 10μl | In stock | $59.90 | |
| Ab093242-50μl | 50μl | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $177.90 | |
| Ab093242-100μl | 100μl | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $327.90 | |
| Ab093242-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,397.90 |
pAb; Rabbit anti Human Caveolin-1 Antibody; WB, IHC; Unconjugated
| Product Name | Caveolin-1 Antibody - Primary antibody, specific to Caveolin-1, Rabbit IgG |
|---|---|
| Synonyms | BSCL3 antibody | CAV antibody | CAV1 antibody | CAV1_HUMAN antibody | caveolae protein, 22 kD antibody | caveolin 1 alpha isoform antibody | caveolin 1 beta isoform antibody | Caveolin 1 caveolae protein 22kDa antibody | Caveolin-1 antibody | Caveolin1 an |
| Specifications & Purity | ExactAb™, Validated, Carrier Free, Azide Free, High performance, Lot by Lot |
| Host species | Rabbit |
| Specificity | Caveolin-1 |
| Immunogen | Recombinant CAV1 expressed in E.coli (AA 2-104) |
| Positive Control | WB: A431, A549 cell lysates and Mouse lung; IHC: Human Thyroid cancer tissue, Human Breast cancer tissue, Mouse Colon tissue, Mouse Cardiac Muscle tissue, Porcine Cerebrum tissue, Porcine Uterus tissue, Human Placenta tissue, Porcine Colon tissue, Porcine |
| Conjugation | Unconjugated |
| Grade | Azide Free, Carrier Free, ExactAb™, High Performance, Validated |
| Note | 20μl卖完停产，不再备货 |
| Product Description | Rabbit anti Human Caveolin-1 Antibody, Polyclonal antibody, could be used for WB, IHC and so on. |
| Isotype | Rabbit IgG |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Antigen affinity purified and protein A purified |
| Form | Liquid |
| Concentration | Lot by Lot |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Caveolin-1 Antibody (Ab093242) - Western Blot
All lanes: Caveolin-1 Antibody (Ab093242) at 1/5000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 20 kDa
Observed band size: 19&21 kDa
Exposure time: 1.8 s
Caveolin-1 Antibody (Ab093242) - Western Blot
All lanes: Caveolin-1 Antibody (Ab093242) at 1/5000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 20 kDa
Observed band size: 22 kDa
Exposure time: 1.8 s
Caveolin-1 Antibody (Ab093242) - IHC
DAB staining on IHC
Samples: Human Thyroid cancer Tissue
Primary Ab: 20µg/mL Caveolin-1 Antibody (Ab093242)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
Caveolin-1 Antibody (Ab093242) - IHC
DAB staining on IHC
Samples: Human Breast cancer Tissue
Primary Ab: 20µg/mL Caveolin-1 Antibody (Ab093242)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
Caveolin-1 Antibody (Ab093242) - IHC
DAB staining on IHC
Sample: Mouse Colon Tissue
Primary Ab: 20µg/mL Caveolin-1 Antibody (Ab093242)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
Caveolin-1 Antibody (Ab093242) - IHC
DAB staining on IHC
Sample: Mouse Cardiac Muscle Tissue
Primary Ab: 20µg/mL Caveolin-1 Antibody (Ab093242)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
Caveolin-1 Antibody (Ab093242) - IHC
DAB staining on IHC
Sample: Porcine Cerebrum Tissue
Primary Ab: 20µg/mL Caveolin-1 Antibody (Ab093242)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
Caveolin-1 Antibody (Ab093242) - IHC
DAB staining on IHC
Sample: Porcine Uterus Tissue
Primary Ab: 20µg/mL Caveolin-1 Antibody (Ab093242)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
Caveolin-1 Antibody (Ab093242) - IHC
DAB staining on IHC
Sample: Human Placenta Tissue
Primary Ab: 20µg/mL Caveolin-1 Antibody (Ab093242)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
Caveolin-1 Antibody (Ab093242) - IHC
DAB staining on IHC
Sample: Porcine Colon Tissue
Primary Ab: 20µg/mL Caveolin-1 Antibody (Ab093242)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
Caveolin-1 Antibody (Ab093242) - IHC
DAB staining on IHC
Sample: Porcine Uterus Tissue
Primary Ab: 20µg/mL Caveolin-1 Antibody (Ab093242)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
Caveolin-1 Antibody (Ab093242) - IHC
DAB staining on IHC
Sample: Porcine Small intestine Tissue
Primary Ab: 20µg/mL Caveolin-1 Antibody (Ab093242)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
Caveolin-1 Antibody (Ab093242) - IHC
DAB staining on IHC
Sample: Porcine Cardiac Muscle Tissue
Primary Ab: 20µg/mL Caveolin-1 Antibody (Ab093242)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
Caveolin-1 Antibody (Ab093242) - IHC
DAB staining on IHC
Sample: Porcine Lymph node Tissue
Primary Ab: 20µg/mL Caveolin-1 Antibody (Ab093242)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
Caveolin-1 Antibody (Ab093242) - IHC
DAB staining on IHC
Sample: Porcine Liver Tissue
Primary Ab: 20µg/mL Caveolin-1 Antibody (Ab093242)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
Caveolin-1 Antibody (Ab093242) - IHC
DAB staining on IHC
Sample: Porcine Lung Tissue
Primary Ab: 20µg/mL Caveolin-1 Antibody (Ab093242)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Application | Dilution info |
|---|---|
| IHC | 5-20 µg/mL |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0202980 | Certificate of Analysis | Mar 01, 2024 | Ab093242 |
| ZJ23F0800937 | Certificate of Analysis | Aug 30, 2023 | Ab093242 |
| ZJ23F0800936 | Certificate of Analysis | Aug 30, 2023 | Ab093242 |
| 1. Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M. (2009) Lysine acetylation targets protein complexes and co-regulates major cellular functions.. Science, 325 (5942): (834-40). [PMID:19608861] [10.1021/op500134e] |
| 2. Gilliam AJ, Smith JN, Flather D, Johnston KM, Gansmiller AM, Fishman DA, Edgar JM, Balk M, Majumdar S, Weiss GA.. (2016) Affinity-Guided Design of Caveolin-1 Ligands for Deoligomerization.. J Med Chem, 59 (8): (4019-4025). [PMID:27010220] [10.1021/acs.jmedchem.5b01536] |
| 3. and Glenney, J R JR.. (1992) The sequence of human caveolin reveals identity with VIP21, a component of transport vesicles.. FEBS letters, (7): [PMID:1360410] |
| 4. Li, S S, Seitz, R R and Lisanti, M P MP.. (1996) Phosphorylation of caveolin by src tyrosine kinases. The alpha-isoform of caveolin is selectively phosphorylated by v-Src in vivo.. The Journal of biological chemistry, (16): [PMID:8632005] |
| 5. Hurlstone, A F AF and 7 more authors.. (1999) Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines.. Oncogene, (11): [PMID:10086342] |
| 6. Engelman, J A JA, Zhang, X L XL and Lisanti, M P MP.. (1999) Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1). Methylation of a CpG island in the 5' promoter region of the caveolin-1 gene in human breast cancer cell lines.. FEBS letters, (9): [PMID:10218480] |
| 7. Vargas, Leonardo L and 6 more authors.. (2002) Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx.. The Journal of biological chemistry, (15): [PMID:11751885] |
| 8. Eberle, Heike B HB and 8 more authors.. (2002) Identification and characterization of a novel human plant pathogenesis-related protein that localizes to lipid-enriched microdomains in the Golgi complex.. Journal of cell science, (15): [PMID:11865038] |
| 9. Lee, Hyangkyu H and 5 more authors.. (2002) Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia.. The American journal of pathology, [PMID:12368209] |
| 10. Vainonen, Julia P JP, Aboulaich, Nabila N, Turkina, Maria V MV, Strålfors, Peter P and Vener, Alexander V AV.. (2004) N-terminal processing and modifications of caveolin-1 in caveolae from human adipocytes.. Biochemical and biophysical research communications, (23): [PMID:15219854] |
| 11. Aboulaich, Nabila N, Vainonen, Julia P JP, Strålfors, Peter P and Vener, Alexander V AV.. (2004) Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes.. The Biochemical journal, (15): [PMID:15242332] |
| 12. Parr, Rebecca D RD and 6 more authors.. (2006) The rotavirus enterotoxin NSP4 directly interacts with the caveolar structural protein caveolin-1.. Journal of virology, [PMID:16501093] |
| 13. Schilling, Kirstin K and 6 more authors.. (2006) Translocation of endothelial nitric-oxide synthase involves a ternary complex with caveolin-1 and NOSTRIN.. Molecular biology of the cell, [PMID:16807357] |
| 14. Ohnuma, Kei K and 10 more authors.. (2007) Caveolin-1 triggers T-cell activation via CD26 in association with CARMA1.. The Journal of biological chemistry, (30): [PMID:17287217] |
| 15. Kim, C A CA and 15 more authors.. (2008) Association of a homozygous nonsense caveolin-1 mutation with Berardinelli-Seip congenital lipodystrophy.. The Journal of clinical endocrinology and metabolism, [PMID:18211975] |
| 16. Cao, Henian H, Alston, Lindsay L, Ruschman, Jennifer J and Hegele, Robert A RA.. (2008) Heterozygous CAV1 frameshift mutations (MIM 601047) in patients with atypical partial lipodystrophy and hypertriglyceridemia.. Lipids in health and disease, (31): [PMID:18237401] |
| 17. Dephoure, Noah N and 6 more authors.. (2008) A quantitative atlas of mitotic phosphorylation.. Proceedings of the National Academy of Sciences of the United States of America, (5): [PMID:18669648] |
| 18. McMahon, Kerrie-Ann KA and 7 more authors.. (2009) SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function.. The EMBO journal, (22): [PMID:19262564] |
| 19. Oppermann, Felix S FS and 7 more authors.. (2009) Large-scale proteomics analysis of the human kinome.. Molecular & cellular proteomics : MCP, [PMID:19369195] |
| 20. Rigbolt, Kristoffer T G KT and 9 more authors.. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.. Science signaling, (15): [PMID:21406692] |
| 21. Ritz, Danilo D and 14 more authors.. (2011) Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations.. Nature cell biology, (7): [PMID:21822278] |
| 22. Austin, Eric D ED and 12 more authors.. (2012) Whole exome sequencing to identify a novel gene (caveolin-1) associated with human pulmonary arterial hypertension.. Circulation. Cardiovascular genetics, [PMID:22474227] |
| 23. Van Damme, Petra P and 15 more authors.. (2012) N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.. Proceedings of the National Academy of Sciences of the United States of America, (31): [PMID:22814378] |
| 24. Zhou, Houjiang H and 6 more authors.. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome.. Journal of proteome research, (4): [PMID:23186163] |
| 25. Kirchner, Philipp P, Bug, Monika M and Meyer, Hemmo H.. (2013) Ubiquitination of the N-terminal region of caveolin-1 regulates endosomal sorting by the VCP/p97 AAA-ATPase.. The Journal of biological chemistry, (8): [PMID:23335559] |
| 26. Bian, Yangyang Y and 9 more authors.. (2014) An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.. Journal of proteomics, (16): [PMID:24275569] |
| 27. Gu, Hong-Mei HM, Wang, Fa-Qi FQ and Zhang, Da-Wei DW.. (2014) Caveolin-1 interacts with ATP binding cassette transporter G1 (ABCG1) and regulates ABCG1-mediated cholesterol efflux.. Biochimica et biophysica acta, [PMID:24576892] |
| 28. Kipper, Sarit S and 7 more authors.. (2015) New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein.. Molecular & cellular proteomics : MCP, [PMID:25556234] |
| 29. Mohan, Jagan J, Morén, Björn B, Larsson, Elin E, Holst, Mikkel R MR and Lundmark, Richard R.. (2015) Cavin3 interacts with cavin1 and caveolin1 to increase surface dynamics of caveolae.. Journal of cell science, (1): [PMID:25588833] |
| 30. Hwangbo, C C and 7 more authors.. (2016) Syntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalization.. Oncogene, (21): [PMID:25893292] |
| 31. Thomas R Burkard,Melanie Planyavsky,Ines Kaupe,Florian P Breitwieser,Tilmann Bürckstümmer,Keiryn L Bennett,Giulio Superti-Furga,Jacques Colinge. (2011-01-29) Initial characterization of the human central proteome.. BMC systems biology, 5 (17-17). [PMID:21269460] |
