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CCG 1423 - 10mM in DMSO, high purity , CAS No.285986-88-1
Rho/SRF pathway inhibitor; induces intermediate mesoderm differentiation from ESCs
Basic Description Synonyms CCG-1423 | 285986-88-1 | CCG1423 | CCG 1423 | n-(2-(4-chloroanilino)-1-methyl-2-oxoethoxy)-3,5-bis(trifluoromethyl)benzamide | N-((1-((4-chlorophenyl)amino)-1-oxopropan-2-yl)oxy)-3,5-bis(trifluoromethyl)benzamide | N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis( Specifications & Purity Moligand™, 10mM in DMSO Biochemical and Physiological Mechanisms Rho/SRF pathway inhibitor; stimulates apoptosis of a melanoma cell line overexpressing RhoC (A375M2). Suppresses Rho-dependent invasion of PC-3 prostate cancer cellsin vitroand inhibits lysophosphatidic acid-induced DNA synthesis in PC-3 prostate cancer c Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Grade Moligand™
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide INCHI InChI=1S/C18H13ClF6N2O3/c1-9(15(28)26-14-4-2-13(19)3-5-14)30-27-16(29)10-6-11(17(20,21)22)8-12(7-10)18(23,24)25/h2-9H,1H3,(H,26,28)(H,27,29) InChi Key DSMXVSGJIDFLKP-UHFFFAOYSA-N Canonical SMILES CC(C(=O)NC1=CC=C(C=C1)Cl)ONC(=O)C2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F Isomeric SMILES CC(C(=O)NC1=CC=C(C=C1)Cl)ONC(=O)C2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F PubChem CID 2726015 Molecular Weight 454.75
Chemical and Physical Properties Sensitivity heat sensitive
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