Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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C275348-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $19.90 | |
C275348-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $35.90 | |
C275348-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $75.90 | |
C275348-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $105.90 | |
C275348-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $189.90 |
Selective CCK B receptor agonist
Synonyms | (S)-4-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-3-((S)-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)-4-(methylthio)butanamido)-4-oxobutanoic acid | F52842 | TETRAGASTRIN [WHO-DD] | L-Triptophyl-L-methyionyl-L-alpha-aspartyl-L-phenylalaninamide | Tetraga |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Selective cholecystokinin B (CCK B ) receptor agonist. Increases secretory activity of mast cells. Anxiogenic agent. Active in vivo and in vitro . |
Storage Temp | Store at -20°C,Desiccated |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description |
Tetragastrin (Cholecystokinin tetrapeptide; CCK-4) is the C-terminal tetrapeptide of gastrin. Tetragastrin can stimulate gastric secretion[1]. Tetragastrin is a Cholecystokinin (CCK-4) receptor agonist[2]. Gastric mucosal protection
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (3S)-3-[[(2S)-2-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid |
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INCHI | InChI=1S/C29H36N6O6S/c1-42-12-11-22(33-27(39)20(30)14-18-16-32-21-10-6-5-9-19(18)21)28(40)35-24(15-25(36)37)29(41)34-23(26(31)38)13-17-7-3-2-4-8-17/h2-10,16,20,22-24,32H,11-15,30H2,1H3,(H2,31,38)(H,33,39)(H,34,41)(H,35,40)(H,36,37)/t20-,22-,23-,24-/m0/s1 |
InChi Key | RGYLYUZOGHTBRF-BIHRQFPBSA-N |
Canonical SMILES | CSCCC(C(=O)NC(CC(=O)O)C(=O)NC(CC1=CC=CC=C1)C(=O)N)NC(=O)C(CC2=CNC3=CC=CC=C32)N |
Isomeric SMILES | CSCC[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)N |
PubChem CID | 446569 |
Molecular Weight | 596.7 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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G2425272 | Certificate of Analysis | Apr 19, 2024 | C275348 |
G2425273 | Certificate of Analysis | Apr 19, 2024 | C275348 |
G2425274 | Certificate of Analysis | Apr 19, 2024 | C275348 |
G2425275 | Certificate of Analysis | Apr 19, 2024 | C275348 |
G2425276 | Certificate of Analysis | Apr 19, 2024 | C275348 |
G2425277 | Certificate of Analysis | Apr 19, 2024 | C275348 |
G2425278 | Certificate of Analysis | Apr 19, 2024 | C275348 |
G2425291 | Certificate of Analysis | Apr 19, 2024 | C275348 |
G2425292 | Certificate of Analysis | Apr 19, 2024 | C275348 |
G2425293 | Certificate of Analysis | Apr 19, 2024 | C275348 |
Solubility | Soluble in DMSO to 1 mg/ml |
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1. Feng H et al.. (2021) The entorhinal cortex modulates trace fear memory formation and neuroplasticity in the mouse lateral amygdala via cholecystokinin.. Elife, 10 [PMID:34779397] |