CCK-4 - ≥98%, high purity , CAS No.1947-37-1

  • ≥98%
Item Number
C275348
Grouped product items
SKUSizeAvailabilityPrice Qty
C275348-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$19.90
C275348-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$35.90
C275348-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$75.90
C275348-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$105.90
C275348-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$189.90

Selective CCK B receptor agonist

Basic Description

Synonyms(S)-4-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-3-((S)-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)-4-(methylthio)butanamido)-4-oxobutanoic acid | F52842 | TETRAGASTRIN [WHO-DD] | L-Triptophyl-L-methyionyl-L-alpha-aspartyl-L-phenylalaninamide | Tetraga
Specifications & Purity≥98%
Biochemical and Physiological MechanismsSelective cholecystokinin B (CCK B ) receptor agonist. Increases secretory activity of mast cells. Anxiogenic agent. Active in vivo and in vitro .
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Tetragastrin (Cholecystokinin tetrapeptide; CCK-4) is the C-terminal tetrapeptide of gastrin. Tetragastrin can stimulate gastric secretion[1]. Tetragastrin is a Cholecystokinin (CCK-4) receptor agonist[2]. Gastric mucosal protection

Associated Targets(Human)

CCKBR Tclin Cholecystokinin B receptor (3550 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Cckar Cholecystokinin A receptor (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (3S)-3-[[(2S)-2-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid
INCHI InChI=1S/C29H36N6O6S/c1-42-12-11-22(33-27(39)20(30)14-18-16-32-21-10-6-5-9-19(18)21)28(40)35-24(15-25(36)37)29(41)34-23(26(31)38)13-17-7-3-2-4-8-17/h2-10,16,20,22-24,32H,11-15,30H2,1H3,(H2,31,38)(H,33,39)(H,34,41)(H,35,40)(H,36,37)/t20-,22-,23-,24-/m0/s1
InChi Key RGYLYUZOGHTBRF-BIHRQFPBSA-N
Canonical SMILES CSCCC(C(=O)NC(CC(=O)O)C(=O)NC(CC1=CC=CC=C1)C(=O)N)NC(=O)C(CC2=CNC3=CC=CC=C32)N
Isomeric SMILES CSCC[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)N
PubChem CID 446569
Molecular Weight 596.7

Certificates

Certificate of Analysis(COA)

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10 results found

Lot NumberCertificate TypeDateItem
G2425272Certificate of AnalysisApr 19, 2024 C275348
G2425273Certificate of AnalysisApr 19, 2024 C275348
G2425274Certificate of AnalysisApr 19, 2024 C275348
G2425275Certificate of AnalysisApr 19, 2024 C275348
G2425276Certificate of AnalysisApr 19, 2024 C275348
G2425277Certificate of AnalysisApr 19, 2024 C275348
G2425278Certificate of AnalysisApr 19, 2024 C275348
G2425291Certificate of AnalysisApr 19, 2024 C275348
G2425292Certificate of AnalysisApr 19, 2024 C275348
G2425293Certificate of AnalysisApr 19, 2024 C275348

Chemical and Physical Properties

SolubilitySoluble in DMSO to 1 mg/ml

Related Documents

References

1. Feng H et al..  (2021)  The entorhinal cortex modulates trace fear memory formation and neuroplasticity in the mouse lateral amygdala via cholecystokinin..  Elife,  10    [PMID:34779397]

Solution Calculators