Basic Description

Synonyms	CCT365623 \| sulfonyl)-thiophene \| 2126134-01-6 \| CHEMBL4441173 \| 5-Aminomethyl-2-(5-methanesulfonyl-biphenyl-3- \| SCHEMBL19259821 \| GTPL10485 \| DTXSID401022526 \| BDBM50501885 \| TQ0080 \| AKOS040748096 \| CCT 365623 \| CCT-365623 \| compound 9f [PMID: 31070916] \| NCGC00510185-01 \| 5-Aminom
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of lysyl oxidase;Inhibitor of lysyl oxidase like 2

Associated Targets(Human)

LOXL2 Tchem Lysyl oxidase homolog 2 (5 Activities)

Discover Target: LOXL2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LOX Tchem Protein-lysine 6-oxidase (0 Activities)

Discover Target: LOX

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAOA Tclin Monoamine oxidase A (11911 Activities)

Discover Target: MAOA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAOB Tclin Monoamine oxidase B (8835 Activities)

Discover Target: MAOB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KCNH2 Tclin HERG (29587 Activities)

Discover Target: KCNH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LOX Tchem Lysyl oxidase (75 Activities)

Discover Target: LOX

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MDA-MB-231 (73002 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LOXL2 Tchem Lysyl oxidase homolog 2 (834 Activities)

Discover Target: LOXL2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LOXL3 Tchem Lysyl oxidase homolog 3 (44 Activities)

Discover Target: LOXL3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

AOC3 Amine oxidase, copper containing (44 Activities)

Discover Target: AOC3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	[5-(3-methylsulfonyl-5-phenylphenyl)sulfonylthiophen-2-yl]methanamine
INCHI	InChI=1S/C18H17NO4S3/c1-25(20,21)16-9-14(13-5-3-2-4-6-13)10-17(11-16)26(22,23)18-8-7-15(12-19)24-18/h2-11H,12,19H2,1H3
InChi Key	ADIBEGOVRYXDOX-UHFFFAOYSA-N
Canonical SMILES	NCc1ccc(s1)S(=O)(=O)c1cc(cc(c1)S(=O)(=O)C)c1ccccc1
Isomeric SMILES	CS(=O)(=O)C1=CC(=CC(=C1)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(S3)CN
PubChem CID	130345035

Database links

PubChem CID	130345035

Certificates

Certificate of Analysis(COA)

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References

1. Leung L, Niculescu-Duvaz D, Smithen D, Lopes F, Callens C, McLeary R, Saturno G, Davies L, Aljarah M, Brown M et al.. (2019) Anti-metastatic Inhibitors of Lysyl Oxidase (LOX): Design and Structure-Activity Relationships.. J Med Chem, 62 (12): (5863-5884). [PMID:31070916]

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SKU	Size	Availability	Price	Qty
C608428-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$730.90
C608428-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,370.90

CCT365623 , CAS No.C608428, Inhibitor of lysyl oxidase;Inhibitor of lysyl oxidase like 2