Basic Description

Synonyms	CCT365623 \| sulfonyl)-thiophene \| 2126134-01-6 \| CHEMBL4441173 \| 5-Aminomethyl-2-(5-methanesulfonyl-biphenyl-3- \| SCHEMBL19259821 \| GTPL10485 \| DTXSID401022526 \| BDBM50501885 \| TQ0080 \| AKOS040748096 \| CCT 365623 \| CCT-365623 \| compound 9f [PMID: 31070916] \| NCGC00510185-01 \| 5-Aminom
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of lysyl oxidase;Inhibitor of lysyl oxidase like 2

Associated Targets(Human)

LOXL2 Tchem Lysyl oxidase homolog 2 (5 Activities)

Discover Target: LOXL2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LOX Tchem Protein-lysine 6-oxidase (0 Activities)

Discover Target: LOX

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAOA Tclin Monoamine oxidase A (11911 Activities)

Discover Target: MAOA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAOB Tclin Monoamine oxidase B (8835 Activities)

Discover Target: MAOB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KCNH2 Tclin HERG (29587 Activities)

Discover Target: KCNH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LOX Tchem Lysyl oxidase (75 Activities)

Discover Target: LOX

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MDA-MB-231 (73002 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LOXL2 Tchem Lysyl oxidase homolog 2 (834 Activities)

Discover Target: LOXL2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

AOC3 Amine oxidase, copper containing (44 Activities)

Discover Target: AOC3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	[5-(3-methylsulfonyl-5-phenylphenyl)sulfonylthiophen-2-yl]methanamine
INCHI	InChI=1S/C18H17NO4S3/c1-25(20,21)16-9-14(13-5-3-2-4-6-13)10-17(11-16)26(22,23)18-8-7-15(12-19)24-18/h2-11H,12,19H2,1H3
InChi Key	ADIBEGOVRYXDOX-UHFFFAOYSA-N
Canonical SMILES	NCc1ccc(s1)S(=O)(=O)c1cc(cc(c1)S(=O)(=O)C)c1ccccc1
Isomeric SMILES	CS(=O)(=O)C1=CC(=CC(=C1)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(S3)CN
PubChem CID	130345035

Database links

PubChem CID	130345035

Certificates

Certificate of Analysis(COA)

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References

1. Leung L, Niculescu-Duvaz D, Smithen D, Lopes F, Callens C, McLeary R, Saturno G, Davies L, Aljarah M, Brown M et al.. (2019) Anti-metastatic Inhibitors of Lysyl Oxidase (LOX): Design and Structure-Activity Relationships.. J Med Chem, 62 (12): (5863-5884). [PMID:31070916] [10.1021/op500134e]

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SKU	Size	Availability	Price	Qty
C608428-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$730.90
C608428-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,370.90

CCT365623 , CAS No.C608428, Inhibitor of lysyl oxidase;Inhibitor of lysyl oxidase like 2