CD 2665 - ≥98%(HPLC), high purity , CAS No.170355-78-9, Antagonist of Retinoic acid receptor-γ

Item Number
C287183
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C287183-1mg
1mg
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$127.90
C287183-5mg
5mg
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$444.90
C287183-10mg
10mg
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$801.90
C287183-25mg
25mg
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C287183-50mg
50mg
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C287183-100mg
100mg
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$5,839.90

Selective RARβ/γ antagonist

Basic Description

SynonymsSCHEMBL14377478 | GTPL2654 | J-010615 | Q27075801 | Benzoic acid, 4-(6-((2-methoxyethoxy)methoxy)-7-tricyclo(3.3.1.1.3,7)dec-1-yl-2-naphthalenyl)- | 4-[6-[(2-Methoxyethoxy)methoxy]-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic acid | AKOS024457807
Specifications & PurityMoligand™, ≥98%(HPLC)
Biochemical and Physiological MechanismsSelective RARβγantagonist (KDvalues are 110, 306 and > 1000 nM for RARγ, RARβand RARαrespectively). Blocks retinoic acid-induced apoptosisex vivo.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeANTAGONIST
Mechanism of actionAntagonist of Retinoic acid receptor-γ

Associated Targets(Human)

RARG Tclin Retinoic acid receptor gamma (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 4-[7-(1-adamantyl)-6-(2-methoxyethoxymethoxy)naphthalen-2-yl]benzoic acid
INCHI InChI=1S/C31H34O5/c1-34-8-9-35-19-36-29-15-26-7-6-25(23-2-4-24(5-3-23)30(32)33)13-27(26)14-28(29)31-16-20-10-21(17-31)12-22(11-20)18-31/h2-7,13-15,20-22H,8-12,16-19H2,1H3,(H,32,33)
InChi Key JBALRFFXKQPVLT-UHFFFAOYSA-N
Canonical SMILES COCCOCOC1=C(C=C2C=C(C=CC2=C1)C3=CC=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5
Isomeric SMILES COCCOCOC1=C(C=C2C=C(C=CC2=C1)C3=CC=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5
PubChem CID 216241
Molecular Weight 486.6

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 48.66, Max Conc. mM: 100

Related Documents

Solution Calculators