Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C287183-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $127.90 | |
C287183-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $444.90 | |
C287183-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $801.90 | |
C287183-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,802.90 | |
C287183-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $3,244.90 | |
C287183-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $5,839.90 |
Selective RARβ/γ antagonist
Synonyms | SCHEMBL14377478 | GTPL2654 | J-010615 | Q27075801 | Benzoic acid, 4-(6-((2-methoxyethoxy)methoxy)-7-tricyclo(3.3.1.1.3,7)dec-1-yl-2-naphthalenyl)- | 4-[6-[(2-Methoxyethoxy)methoxy]-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic acid | AKOS024457807 |
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Specifications & Purity | Moligand™, ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | Selective RARβγantagonist (KDvalues are 110, 306 and > 1000 nM for RARγ, RARβand RARαrespectively). Blocks retinoic acid-induced apoptosisex vivo. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ANTAGONIST |
Mechanism of action | Antagonist of Retinoic acid receptor-γ |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | 4-[7-(1-adamantyl)-6-(2-methoxyethoxymethoxy)naphthalen-2-yl]benzoic acid |
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INCHI | InChI=1S/C31H34O5/c1-34-8-9-35-19-36-29-15-26-7-6-25(23-2-4-24(5-3-23)30(32)33)13-27(26)14-28(29)31-16-20-10-21(17-31)12-22(11-20)18-31/h2-7,13-15,20-22H,8-12,16-19H2,1H3,(H,32,33) |
InChi Key | JBALRFFXKQPVLT-UHFFFAOYSA-N |
Canonical SMILES | COCCOCOC1=C(C=C2C=C(C=CC2=C1)C3=CC=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5 |
Isomeric SMILES | COCCOCOC1=C(C=C2C=C(C=CC2=C1)C3=CC=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5 |
PubChem CID | 216241 |
Molecular Weight | 486.6 |
PubChem CID | 216241 |
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CAS Registry No. | 170355-78-9 |
NURSA Ligand | 10.1621/82V95MTEPT |
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Solubility | Solvent:DMSO, Max Conc. mg/mL: 48.66, Max Conc. mM: 100 |
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