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CD11a Mouse mAb - Primary antibody, specific to CD11a, Mouse IgG2a

    Application:
  • Flow Cytometry
  • IF/ICC
  • IHC
  • IP
  • WB
Features and benefitsView More
  • Host species: Mouse
  • Species reactivity(Reacts with): Human
  • Isotype: Mouse IgG2a
  • Clone Number: 38
  • Conjugation: Unconjugated
Item Number
Ab093709
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab093709-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$29.90
Ab093709-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab093709-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$99.90
Ab093709-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$699.90

mAb (38); Mouse anti Human CD11a Antibody; Flow, WB, IHC, IF, ICC, IP; Unconjugated

Basic Description

Product NameCD11a Mouse mAb - Primary antibody, specific to CD11a, Mouse IgG2a
SynonymsCD11A | CD11 antigen-like family member A | CD11a antigen | CD11a | CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide | Integrin alpha L | integrin alpha-L | integrin gene promoter | integrin, alpha L (antigen CD11A (p1
Specifications & PurityCarrier Free, Low Endotoxin, Azide Free, Validated, ≥95%(SDS-PAGE&HPLC), See COA
Host speciesMouse
SpecificityCD11a
ConjugationUnconjugated
GradeAzide Free, Carrier Free, Low Endotoxin, Validated
Product Description

Mouse anti Human CD11a Antibody, Monoclonal (38), could be used for Flow, WB, IHC, IF, ICC, IP and so on.
Application
Flow: Use at an assay dependent concentration.
WB: Use at an assay dependent concentration.
IHC: Use at an assay dependent concentration.
ICC/IF: Use at an assay dependent concentration.
IP: Use at an assay dependent concentration.
Protein Function
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.

Product Properties

IsotypeMouse IgG2a
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
ConcentrationSee COA
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

CD11a Mouse mAb (Ab093709) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD11a with CD11a Mouse mAb (Ab093709) conjugated with biotin (right panel) at 0.5 μg/mL for 1 hour at 4°C, compared with Mouse IgG Isotype Control Antibody (Biotin) (Ab180306) (left panel) and detected with SA-PE (rp156150).

CD11a Mouse mAb (Ab093709) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD11a (red) with CD11a Mouse mAb (Ab093709) conjugated with biotin at 0.5 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Mouse IgG Isotype Control Antibody (Biotin) (Ab180306). Black - Unlabelled control, cells without incubation with primary antibody.

CD11a Mouse mAb (Ab093709) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling CD11a (red) with CD11a Mouse mAb (Ab093709) at 0.5 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

Associated Targets(Human)

ITGAL Tclin Integrin alpha-L (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ITGAL Tclin Leukocyte adhesion glycoprotein LFA-1 alpha (170 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ITGAL Tclin Intercellular adhesion molecule (ICAM-1), Integrin alpha-L/beta-2 (760 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences
Leukocyte adhesion glycoprotein LFA-1 alpha inhibitorINHIBITORALA1803Leukocyte adhesion glycoprotein LFA-1 alphaSINGLE PROTEINHomo sapiens

PubMed: [1]


Integrin alpha-L/beta-2 (LFA-1) inhibitorINHIBITORALA2364172Integrin alpha-L/beta-2 (LFA-1)PROTEIN COMPLEXHomo sapiensAlpha subunit is binding site

FDA: [1]


Integrin alpha-L/beta-2 (LFA-1) antagonistANTAGONISTALA2364172Integrin alpha-L/beta-2 (LFA-1)PROTEIN COMPLEXHomo sapiensBinds with high-affinity to the site I domain of the aL subunit on LFA-1

PubMed: [1]


Integrin alpha-L/beta-2 (LFA-1) antagonistANTAGONISTALA2364172Integrin alpha-L/beta-2 (LFA-1)PROTEIN COMPLEXHomo sapiens

PubMed: [1] , [2]


Application

ApplicationDilution info
WBUse at an assay dependent concentration.

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Use at an assay dependent concentration.

IPUse at an assay dependent concentration.

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Use at an assay dependent concentration.

IHCUse at an assay dependent concentration.

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Use at an assay dependent concentration.

IF/ICCUse at an assay dependent concentration.

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Use at an assay dependent concentration.

Flow CytometryUse at an assay dependent concentration.

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Use at an assay dependent concentration.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
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Related Documents

Solution Calculators