| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab191609-10T (Trial Size) Apply for free trial size（?） Every year, as a valued customer, you have the exclusive opportunity to explore and enjoy three different trial products of your choice, absolutely free! | 10T | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 | |
| Ab191609-25T | 25T | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $129.90 | |
| Ab191609-100T | 100T | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $319.90 |
mAb (ICRF44); Mouse anti Human CD11b Antibody (AF405); Flow Cytometry
| Product Name | CD11b Mouse mAb (AF405) |
|---|---|
| Synonyms | CD11B | antigen CD11b (p170) | CD11 antigen-like family member B | CD11b antigen | Cell surface glycoprotein MAC-1 subunit alpha | Complement component 3 receptor 3 subunit | CR-3 alpha chain | CR3A | CR3AMGC117044 | Integrin alpha M | integrin alpha-M | |
| Specifications & Purity | ExactAb™, Validated, Ex:401nm, Em:422nm, 5 μL/test |
| Biochemical and Physiological Mechanisms | Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third |
| Host species | Mouse |
| Specificity | CD11b |
| Immunogen | Rheumatoid synovial cells and human monocytes. |
| Positive Control | Flow: Human peripheral blood monocytes |
| Conjugation | Alexa Fluor® 405 |
| Grade | Em:422nm, Ex:401nm, ExactAb™, Validated |
| Product Description |
Mouse anti Human CD11b Antibody, Monoclonal (ICRF44), could be used for Flow, WB, IHC, IP and so on.
|
| Light Chain Type | kappa |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Protein G purified |
| Concentration | 5 μL/test |
| Storage Temp | Store at 2-8°C,Protected from light,Freeze prohibited |
| Shipped In | Wet ice |
| Stability And Storage | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
CD11b Mouse mAb (AF405) (Ab191609) - Flow Cytometry
Flow cytometry analysis of CD11b expression by human peripheral blood (right panel) compared to an isotype control (left panel). Cells were stained with CD11b Mouse mAb (AF405) (Ab191609) at 5μL/test for 1 hour at 4°C. Left panel - Mouse IgG (AF405) (Ab190076).
CD11b Mouse mAb (AF405) (Ab191609) - Flow Cytometry
Flow cytometry analysis of CD11b expression by human peripheral blood monocytes (red) compared to an isotype control (blue). Cells were stained with CD11b Mouse mAb (AF405) (Ab191609) at 5μL/test for 1 hour at 4°C. Blue - Mouse IgG (AF405) (Ab190076). Black - Unlabelled control, cells without incubation with primary antibody.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Application | Dilution info |
|---|---|
| Flow Cytometry |
5 μL/test,
the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood
|
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