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CD11b Mouse mAb - Primary antibody, specific to CD11b, Mouse IgG1

    Application:
  • Flow Cytometry
  • IHC
  • IP
  • WB
Features and benefitsView More
  • Host species: Mouse
  • Species reactivity(Reacts with): Human
  • Isotype: Mouse IgG1
  • Clone Number: ICRF44
  • Conjugation: Unconjugated
Item Number
Ab093725
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab093725-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$19.90
Ab093725-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$39.90
Ab093725-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
Ab093725-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$369.90

mAb (ICRF44); Mouse anti Human CD11b Antibody; Flow, WB, IHC, IP; Unconjugated

Basic Description

Product NameCD11b Mouse mAb - Primary antibody, specific to CD11b, Mouse IgG1
SynonymsCD11B | antigen CD11b (p170) | CD11 antigen-like family member B | CD11b antigen | CD11b | Cell surface glycoprotein MAC-1 subunit alpha | Complement component 3 receptor 3 subunit | CR-3 alpha chain | CR3A | CR3AMGC117044 | Integrin alpha M | integrin al
Specifications & PurityCarrier Free, Low Endotoxin, Azide Free, Validated, ≥95%(SDS-PAGE&HPLC), See COA
Host speciesMouse
SpecificityCD11b
ImmunogenRheumatoid synovial cells and human monocytes.
ConjugationUnconjugated
GradeAzide Free, Carrier Free, Low Endotoxin, Validated
Product Description

Mouse anti Human CD11b Antibody, Monoclonal (ICRF44), could be used for Flow, WB, IHC, IP and so on.
Application
Flow: ≤ 1.0µg/100w cells  
WB: Use at an assay dependent concentration.
IP: Use at an assay dependent concentration.
IHC: Use at an assay dependent concentration.
Protein Function
Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

Product Properties

IsotypeMouse IgG1
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein G purified
FormLiquid
ConcentrationSee COA
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

CD11b Mouse mAb (Ab093725) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD11b with CD11b Mouse mAb (Ab093725) conjugated with biotin (right panel) at 0.5 μg/mL for 1 hour at 4°C, compared with Mouse IgG Isotype Control Antibody (Biotin) (Ab180306) (left panel) and detected with SA-PE (rp156150). 

CD11b Mouse mAb (Ab093725) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD11b (red) with CD11b Mouse mAb (Ab093725) conjugated with biotin at 0.5 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Mouse IgG Isotype Control Antibody (Biotin) (Ab180306). Black - Unlabelled control, cells without incubation with primary antibody.

Associated Targets(Human)

ITGAM Tbio Integrin alpha-M (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WBUse at an assay dependent concentration.

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Use at an assay dependent concentration.

IPUse at an assay dependent concentration.

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Use at an assay dependent concentration.

IHCUse at an assay dependent concentration.

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Use at an assay dependent concentration.

Flow Cytometry

≤ 1.0µg/100w cells  

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Enter lot number to search for analytical chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0707917Certificate of AnalysisJul 08, 2024 Ab093725
ZJ24F0707916Certificate of AnalysisJul 08, 2024 Ab093725
ZJ24F0707915Certificate of AnalysisJul 08, 2024 Ab093725

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