mAb (MI15); Mouse anti Human Syndecan-1 Antibody; Flow; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab129996-10μg | 10μg | In stock | $29.90 | |
| Ab129996-50μg | 50μg | In stock | $89.90 | |
| Ab129996-100μg | 100μg | In stock | $129.90 | |
| Ab129996-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,099.90 |
mAb (MI15); Mouse anti Human Syndecan-1 Antibody; Flow; Unconjugated
| Product Name | CD138/Syndecan-1 Mouse mAb - Primary antibody, specific to Syndecan-1, Mouse IgG1 |
|---|---|
| Synonyms | CD138 antigen; CD138; SDC; SDC1; SYND1heparan sulfate proteoglycan fibroblast growth factor receptor; syndecan 1; syndecan proteoglycan 1; syndecan; Syndecan1; Syndecan-1; CD_antigen antibody; CD138 antibody; CD138 antigen antibody; heparan sulfate proteo |
| Specifications & Purity | ExactAb™, Validated, Carrier Free, Lot by Lot |
| Host species | Mouse |
| Specificity | Syndecan-1 |
| Immunogen | Human U266 and XG-1 Myeloma Cell Lines |
| Conjugation | Unconjugated |
| Grade | Carrier Free, ExactAb™, Validated |
| Product Description | Mouse anti Human CD138/Syndecan-1 Antibody, Monoclonal (MI15), could be used for Flow and so on. Application Flow: < 0.5 μg/100w cells Protein Function Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. |
| Isotype | Mouse IgG1 |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | Lot by Lot |
| Storage Temp | Store at 2-8°C |
| Shipped In | Wet ice |
| Stability And Storage | Shipped at 4°C. Store at 4°C long term (36 months). Upon delivery aliquot. |
CD138/Syndecan-1 Mouse mAb (Ab129996) - Flow Cytometry
Flow Cytometry analysis of U266 cells labelling CD138/Syndecan-1 (red) with CD138/Syndecan-1 Mouse mAb (Ab129996) at 0.5 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Application | Dilution info |
|---|---|
| Flow Cytometry | < 0.5µg/100w cells |
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| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0303652 | Certificate of Analysis | Mar 25, 2024 | Ab129996 |
| ZJ24F0303653 | Certificate of Analysis | Mar 25, 2024 | Ab129996 |
| ZJ24F0303654 | Certificate of Analysis | Mar 25, 2024 | Ab129996 |
| 1. Lories, V V, Cassiman, J J JJ, Van den Berghe, H H and David, G G.. (1992) Differential expression of cell surface heparan sulfate proteoglycans in human mammary epithelial cells and lung fibroblasts.. The Journal of biological chemistry, (15): [PMID:1339431] |
| 2. Mali, M M, Jaakkola, P P, Arvilommi, A M AM and Jalkanen, M M.. (1990) Sequence of human syndecan indicates a novel gene family of integral membrane proteoglycans.. The Journal of biological chemistry, (25): [PMID:2324102] |
| 3. Kaukonen, J J, Alanen-Kurki, L L, Jalkanen, M M and Palotie, A A.. (1997) The mapping and visual ordering of the human syndecan-1 and N-myc genes near the telomeric region of chromosome 2p.. Human genetics, [PMID:9050911] |
| 4. Mennerich, D D and 8 more authors.. (2004) Shift of syndecan-1 expression from epithelial to stromal cells during progression of solid tumours.. European journal of cancer (Oxford, England : 1990), [PMID:15177497] |
| 5. Hillier, Ladeana W LW and 121 more authors.. (2005) Generation and annotation of the DNA sequences of human chromosomes 2 and 4.. Nature, (7): [PMID:15815621] |
| 6. Bhatt, Ami S AS, Erdjument-Bromage, Hediye H, Tempst, Paul P, Craik, Charles S CS and Moasser, Mark M MM.. (2005) Adhesion signaling by a novel mitotic substrate of src kinases.. Oncogene, (11): [PMID:16007225] |
| 7. Baietti, Maria Francesca MF and 11 more authors.. (2012) Syndecan-syntenin-ALIX regulates the biogenesis of exosomes.. Nature cell biology, (3): [PMID:22660413] |
| 8. Liu, Xu X, Shepherd, Tyson R TR, Murray, Ann M AM, Xu, Zhen Z and Fuentes, Ernesto J EJ.. (2013) The structure of the Tiam1 PDZ domain/ phospho-syndecan1 complex reveals a ligand conformation that modulates protein dynamics.. Structure (London, England : 1993), (5): [PMID:23395182] |
