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CD154/CD40L Mouse mAb - Primary antibody, specific to TRAP/CD40L, Mouse IgG2a

  • Azide Free
  • Carrier Free
  • Validated
  • ≥95%(SDS-PAGE)
  • Lot by Lot
Features and benefits
  • Short Overview:

    mAb (5C8); Mouse anti Human/Monkey CD154/CD40L Antibody; in vitro blocking of CD40/CD40L signaling, in vivo blocking of CD40/CD40L signaling, IP, Flow; Unconjugated

  • Species reactivity(Reacts with): Human,Monkey
  • Isotype: Mouse IgG2a
    Application:
  • Animal Model
  • Blocking
  • Flow Cytometry
  • Functional Assay
  • IP
Item Number
Ab132316
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab132316-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
Ab132316-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$139.90
Ab132316-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
Ab132316-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$999.90

mAb (5C8); Mouse anti Human/Monkey CD154/CD40L Antibody; in vitro blocking of CD40/CD40L signaling, in vivo blocking of CD40/CD40L signaling, IP, Flow; Unconjugated

Basic Description

Product NameCD154/CD40L Mouse mAb - Primary antibody, specific to TRAP/CD40L, Mouse IgG2a
Specifications & PurityValidated, Azide Free, Carrier Free, ≥95%(SDS-PAGE), Lot by Lot
Host speciesMouse
SpecificityTRAP/CD40L
ImmunogenHuman D1.1 T cell line
ConjugationUnconjugated
GradeAzide Free, Carrier Free, Validated
Product Description

Mouse anti Human/Monkey CD154/CD40L Antibody, Monoclonal (5C8), could be used for in vitro blocking of CD40/CD40L signaling, in vivo blocking of CD40/CD40L signaling, IP, Flow and so on.

Application:
in vitro blocking of CD40/CD40L signaling: Use at an assay dependent concentration.

in vivo blocking of CD40/CD40L signaling: Use at an assay dependent concentration.

IP: Use at an assay dependent concentration.

Flow: Use at an assay dependent concentration.
Protein Function
Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching.
Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.

Product Properties

IsotypeMouse IgG2a
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein G purified
FormLiquid
ConcentrationLot by Lot
Storage TempStore at 2-8°C,Freeze prohibited
Shipped InWet ice
Stability And StorageShipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon delivery aliquot.

Associated Targets

CD40LG Tbio CD40 ligand 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
IP

Use at an assay dependent concentration.

Flow

Use at an assay dependent concentration.

in vitro blocking of CD40/CD40L signaling

Use at an assay dependent concentration

in vivo blocking of CD40/CD40L signaling

Use at an assay dependent concentration

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

Solution Calculators