mAb (5C8); Mouse anti Human/Monkey CD154/CD40L Antibody; in vitro blocking of CD40/CD40L signaling, in vivo blocking of CD40/CD40L signaling, IP, Flow; Unconjugated
Validated, Azide Free, Carrier Free, ≥95%(SDS-PAGE), Lot by Lot
Host species
Mouse
Specificity
TRAP/CD40L
Immunogen
Human D1.1 T cell line
Conjugation
Unconjugated
Grade
Azide Free, Carrier Free, Validated
Product Description
Mouse anti Human/Monkey CD154/CD40L Antibody, Monoclonal (5C8), could be used for in vitro blocking of CD40/CD40L signaling, in vivo blocking of CD40/CD40L signaling, IP, Flow and so on.
Application: in vitro blocking of CD40/CD40L signaling: Use at an assay dependent concentration.
in vivo blocking of CD40/CD40L signaling: Use at an assay dependent concentration.
IP: Use at an assay dependent concentration.
Flow: Use at an assay dependent concentration. Protein Function Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.
Product Properties
Isotype
Mouse IgG2a
Light Chain Type
kappa
SDS-PAGE
150 kDa
Purification Method
Protein G purified
Form
Liquid
Concentration
Lot by Lot
Storage Temp
Store at 2-8°C,Freeze prohibited
Shipped In
Wet ice
Stability And Storage
Shipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon delivery aliquot.
