| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab006551-10μl | 10μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $66.90 | |
| Ab006551-20μl | 20μl | In stock | $89.90 |
mAb (C8); Mouse anti Human CD1a Antibody; WB; Unconjugated
| Product Name | CD1a Mouse mAb - Primary antibody, specific to CD1a, Mouse IgG1 |
|---|---|
| Synonyms | hTa1 thymocyte antigen | T-cell surface antigen T6/Leu-6 |
| Specifications & Purity | ExactAb™, Validated, Carrier Free, Azide Free, Lot by Lot |
| Host species | Mouse |
| Specificity | CD1a |
| Immunogen | Recombinant CD1a expressed in E.coli (AA 17-300) |
| Positive Control | WB: K562 and MOLT-4 cell lysates. |
| Conjugation | Unconjugated |
| Grade | Azide Free, Carrier Free, ExactAb™, Validated |
| Note | 20μl卖完停产，不再备货 |
| Product Description | Mouse anti Human CD1a Antibody, Monoclonal (C8), could be used for WB and so on. |
| Isotype | Mouse IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A and Protein G purified |
| Form | Liquid |
| Concentration | Lot by Lot |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
CD1a Mouse mAb (Ab006551) - Western Blot
All lanes: CD1a Mouse mAb (Ab006551) at 1/500 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution
Predicted band size: 37 kDa
Observed band size: 37 kDa
Exposure time: 60.0 s
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB |
0.01-2 µg/mL
|
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ23F1202089 | Certificate of Analysis | Dec 20, 2023 | Ab006551 |
| ZJ23F1202090 | Certificate of Analysis | Dec 20, 2023 | Ab006551 |
| ZJ23F1202091 | Certificate of Analysis | Dec 19, 2023 | Ab006551 |
| 1. Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K et al.. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs.. Nat Genet, 36 (1): (40-5). [PMID:14702039] [10.1021/op500134e] |
| 2. Martin, L H LH, Calabi, F F, Lefebvre, F A FA, Bilsland, C A CA and Milstein, C C.. (1987) Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1c.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:2447586] |
| 3. Aruffo, A A and Seed, B B.. (1989) Expression of cDNA clones encoding the thymocyte antigens CD1a, b, c demonstrates a hierarchy of exclusion in fibroblasts.. Journal of immunology (Baltimore, Md. : 1950), (1): [PMID:2701945] |
| 4. Longley, J J, Kraus, J J, Alonso, M M and Edelson, R R.. (1989) Molecular cloning of CD1a (T6), a human epidermal dendritic cell marker related to class I MHC molecules.. The Journal of investigative dermatology, [PMID:2784820] |
| 5. Calabi, F F and Milstein, C C.. (1986) A novel family of human major histocompatibility complex-related genes not mapping to chromosome 6.. Nature, [PMID:3093894] |
| 6. Martin, L H LH, Calabi, F F and Milstein, C C.. (1986) Isolation of CD1 genes: a family of major histocompatibility complex-related differentiation antigens.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:3097645] |
| 7. Han, M M, Hannick, L I LI, DiBrino, M M and Robinson, M A MA.. (1999) Polymorphism of human CD1 genes.. Tissue antigens, [PMID:10488738] |
| 8. Chen, X X, Ji, Z L ZL and Chen, Y Z YZ.. (2002) TTD: Therapeutic Target Database.. Nucleic acids research, (1): [PMID:11752352] |
| 9. Zajonc, Dirk M DM, Elsliger, Marc A MA, Teyton, Luc L and Wilson, Ian A IA.. (2003) Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 A.. Nature immunology, [PMID:12833155] |
| 10. Zajonc, Dirk M DM and 12 more authors.. (2005) Molecular mechanism of lipopeptide presentation by CD1a.. Immunity, [PMID:15723809] |
| 11. Vincent, Michael S MS, Xiong, Xiaowei X, Grant, Ethan P EP, Peng, Wei W and Brenner, Michael B MB.. (2005) CD1a-, b-, and c-restricted TCRs recognize both self and foreign antigens.. Journal of immunology (Baltimore, Md. : 1950), (15): [PMID:16272286] |
| 12. Gregory, S G SG and 178 more authors.. (2006) The DNA sequence and biological annotation of human chromosome 1.. Nature, (18): [PMID:16710414] |
| 13. Sloma, Ivan I and 9 more authors.. (2008) Regulation of CD1a surface expression and antigen presentation by invariant chain and lipid rafts.. Journal of immunology (Baltimore, Md. : 1950), (15): [PMID:18178838] |
| 14. Birkinshaw, Richard W and 10 more authors.. (2015) αβ T cell antigen receptor recognition of CD1a presenting self lipid ligands.. Nature immunology, [PMID:25642819] |
