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CD20 Mouse mAb - Primary antibody, specific to CD20, Mouse IgG2b

    Application:
  • Animal Model
  • Depletion
  • Flow Cytometry
  • Functional Assay
  • IHC
  • IP
Features and benefitsView More
  • Host species: Mouse
  • Species reactivity(Reacts with): Human,Monkey
  • Isotype: Mouse IgG2b
  • Clone Number: 2H7
  • Conjugation: Unconjugated
Item Number
Ab094175
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab094175-10μg
10μg
In stock
$29.90
Ab094175-50μg
50μg
In stock
$49.90
Ab094175-100μg
100μg
In stock
$69.90
Ab094175-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$599.90

mAb (2H7); Mouse anti Human/Monkey CD20 Antibody; Flow, IHC, IP, in vivo B cell depletion in hCD20 Tg mice; Unconjugated

Basic Description

Product NameCD20 Mouse mAb - Primary antibody, specific to CD20, Mouse IgG2b
SynonymsFMC7 | B1 | B-lymphocyte antigen CD20 | B-lymphocyte cell-surface antigen B1 | B-lymphocyte surface antigen B1 | Bp35 | Bp35MGC3969 | CD20 antigen | CD20 receptor | CD20 | CD20S7 | CVID5 | LEU-16 | Leukocyte surface antigen Leu-16 | Ly-44 | Membrane-spann
Specifications & PurityCarrier Free, Azide Free, Validated, ≥95%(SDS-PAGE), See COA
Host speciesMouse
SpecificityCD20
ImmunogenHuman tonsillar B cells
ConjugationUnconjugated
GradeAzide Free, Carrier Free, Validated
Product Description

Mouse anti Human/Monkey CD20 Antibody, Monoclonal (2H7), could be used for Flow, IHC, IP, in vivo B cell depletion in hCD20 Tg mice and so on.
Application:
Flow: Use at an assay dependent concentration.
IHC: Use at an assay dependent concentration.
IP: Use at an assay dependent concentration.
in vivo B cell depletion in hCD20 Tg mice: Use at an assay dependent concentration.
Protein Function
This protein may be involved in the regulation of B-cell activation and proliferation.

Product Properties

IsotypeMouse IgG2b
Light Chain Typekappa
Purification MethodProtein A purified
FormLiquid
ConcentrationSee COA
Storage TempStore at 2-8°C,Freeze prohibited
Shipped InWet ice
Stability And StorageShipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon delivery aliquot.

Images

CD20 Mouse mAb (Ab094175) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD20 with CD20 Mouse mAb (Ab094175) conjugated with biotin (right panel) at 0.5 μg/mL for 1 hour at 4°C, compared with Mouse IgG Isotype Control Antibody (Biotin) (Ab180306) (left panel) and detected with SA-PE (rp156150).

CD20 Mouse mAb (Ab094175) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD20 (red) with CD20 Mouse mAb (Ab094175) conjugated with biotin at 0.5 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Mouse IgG Isotype Control Antibody (Biotin) (Ab180306). Black - Unlabelled control, cells without incubation with primary antibody.

CD20 Mouse mAb (Ab094175) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD20 (red) with CD20 Mouse mAb (Ab094175) at 0.5 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

Associated Targets(Human)

MS4A1 Tclin B-lymphocyte antigen CD20 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences
B-lymphocyte antigen CD20 binding agentBINDING AGENTALA2058B-lymphocyte antigen CD20SINGLE PROTEINHomo sapiens

DailyMed: [1]


B-lymphocyte antigen CD20 binding agentBINDING AGENTALA2058B-lymphocyte antigen CD20SINGLE PROTEINHomo sapiens

DailyMed: [1]


B-lymphocyte antigen CD20 binding agentBINDING AGENTALA2058B-lymphocyte antigen CD20SINGLE PROTEINHomo sapiens

DailyMed: [1]


B-lymphocyte antigen CD20 binding agentBINDING AGENTALA2058B-lymphocyte antigen CD20SINGLE PROTEINHomo sapiens

FDA: [1]


B-lymphocyte antigen CD20 binding agentBINDING AGENTALA2058B-lymphocyte antigen CD20SINGLE PROTEINHomo sapiens

FDA: [1]


PubMed: [1]


B-lymphocyte antigen CD20 binding agentBINDING AGENTALA2058B-lymphocyte antigen CD20SINGLE PROTEINHomo sapiens

PubMed: [1]


B-lymphocyte antigen CD20 binding agentBINDING AGENTALA2058B-lymphocyte antigen CD20SINGLE PROTEINHomo sapiens

PubMed: [1]


B-lymphocyte antigen CD20 binding agentBINDING AGENTALA2058B-lymphocyte antigen CD20SINGLE PROTEINHomo sapiens

PubMed: [1] , [2]


B-lymphocyte antigen CD20 binding agentBINDING AGENTALA2058B-lymphocyte antigen CD20SINGLE PROTEINHomo sapiens

PubMed: [1] , [2] , [3] , [4] , [5] , [6]


B-lymphocyte antigen CD20 binding agentBINDING AGENTALA2058B-lymphocyte antigen CD20SINGLE PROTEINHomo sapiens

PubMed: [1]


Application

ApplicationDilution info
IPUse at an assay dependent concentration.

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Use at an assay dependent concentration.

IHCUse at an assay dependent concentration.

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Use at an assay dependent concentration.

Flow CytometryUse at an assay dependent concentration.

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Use at an assay dependent concentration.

in vivo B cell depletion in hCD20 Tg mice

Use at an assay dependent concentration.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Enter lot number to search for analytical chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0707926Certificate of AnalysisJul 08, 2024 Ab094175
ZJ24F0707925Certificate of AnalysisJul 08, 2024 Ab094175
ZJ24F0707924Certificate of AnalysisJul 08, 2024 Ab094175

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