CD22 Mouse mAb - Primary antibody, specific to CD22, Mouse IgG1
Specifications & Purity
ExactAb™, Validated, Carrier Free, Lot by Lot
Host species
Mouse
Specificity
CD22
Conjugation
Unconjugated
Grade
Carrier Free, ExactAb™, Validated
Product Description
Mouse anti Human CD22 Antibody, Monoclonal (HIB22), could be used for Flow and so on. Application: Flow: ＜0.5µg/100w cells Protein Function Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Product Properties
Isotype
Mouse IgG1
Light Chain Type
kappa
SDS-PAGE
150 kDa
Purification Method
Protein A purified
Form
Liquid
Concentration
Lot by Lot
Storage Temp
Store at 2-8°C
Shipped In
Wet ice
Stability And Storage
Shipped at 4°C. Store at 4°C long term (36 months). Upon delivery aliquot.
Images
CD22 Mouse mAb (Ab006558) - Flow Cytometry Flow Cytometry analysis of Raji cells labelling CD22 (red) with CD22 Mouse mAb (Ab006558) at 0.1 μg/mL for 1 hour at 4°C. AffiniPure Goat anti-Mouse IgG, Fcγ fragment specific (Alexa Fluor® 647) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.
ZJ24F0102459