| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab006720-10μl | 10μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $59.90 | |
| Ab006720-50μl | 50μl | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $179.90 | |
| Ab006720-100μl | 100μl | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $299.90 | |
| Ab006720-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $769.90 |
pAb; Rabbit anti Human CD23 Antibody; WB, IHC; Unconjugated
| Product Name | CD23 Antibody - Primary antibody, specific to CD23, Rabbit IgG |
|---|---|
| Synonyms | BLAST-2 | C-type lectin domain family 4 member J | Fc-epsilon-RII | Immunoglobulin E-binding factor | Lymphocyte IgE receptor |
| Specifications & Purity | ExactAb™, Validated, Carrier Free, Azide Free, Lot by Lot |
| Host species | Rabbit |
| Specificity | CD23 |
| Immunogen | Recombinant CD23 expressed in E.coli (AA 151-321) |
| Positive Control | WB: NIH/3T3, Raw264.7 and Raji cell lysates. IHC: Human Tonsil tissue, Human Amygdalitis tissue. |
| Conjugation | Unconjugated |
| Grade | Azide Free, Carrier Free, ExactAb™, Validated |
| Note | 20μl卖完停产，不再备货 |
| Product Description | Rabbit anti Human CD23 Antibody, Polyclonal, could be used for WB, IHC and so on. |
| Isotype | Rabbit IgG |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Antigen affinity purified and protein A purified |
| Form | Liquid |
| Concentration | Lot by Lot |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
CD23 Antibody (Ab006720) - Western Blot
All lanes: CD23 Antibody (Ab006720) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 36 kDa
Observed band size: 36, 40 kDa
Exposure time: 22.9 s
CD23 Antibody (Ab006720) - IHC
DAB staining on IHC
Samples: Human Tonsil Tissue
Primary Ab: 10 µg/mL CD23 Antibody (Ab006720)
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
CD23 Antibody (Ab006720) - IHC
DAB staining on IHC
Samples: Human Amygdalitis Tissue
Primary Ab: 20 μg/mL CD23 Antibody (Ab006720)
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Application | Dilution info |
|---|---|
| IHC | 5-20 µg/mL |
| WB | 0.5-2 µg/mL |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ23F1001289 | Certificate of Analysis | Oct 13, 2023 | Ab006720 |
| ZJ23F1001288 | Certificate of Analysis | Oct 13, 2023 | Ab006720 |
| 1. Yokota A, Kikutani H, Tanaka T, Sato R, Barsumian EL, Suemura M, Kishimoto T. (1988) Two species of human Fc epsilon receptor II (Fc epsilon RII/CD23): tissue-specific and IL-4-specific regulation of gene expression.. Cell, 55 (4): (611-8). [PMID:2972386] [10.1021/op500134e] |
| 2. Rose, K K and 8 more authors.. (1992) Partial characterization of natural and recombinant human soluble CD23.. The Biochemical journal, (15): [PMID:1417742] |
| 3. Pirron, U U, Schlunck, T T, Prinz, J C JC and Rieber, E P EP.. (1990) IgE-dependent antigen focusing by human B lymphocytes is mediated by the low-affinity receptor for IgE.. European journal of immunology, [PMID:2167225] |
| 4. Kikutani, H H and 9 more authors.. (1986) Molecular structure of human lymphocyte receptor for immunoglobulin E.. Cell, (5): [PMID:2877743] |
| 5. Ikuta, K K and 7 more authors.. (1987) Human lymphocyte Fc receptor for IgE: sequence homology of its cloned cDNA with animal lectins.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:2949326] |
| 6. Lüdin, C C and 8 more authors.. (1987) Cloning and expression of the cDNA coding for a human lymphocyte IgE receptor.. The EMBO journal, [PMID:3034567] |
| 7. Vouldoukis, I I and 7 more authors.. (1995) The killing of Leishmania major by human macrophages is mediated by nitric oxide induced after ligation of the Fc epsilon RII/CD23 surface antigen.. Proceedings of the National Academy of Sciences of the United States of America, (15): [PMID:7544003] |
| 8. Padlan, E A EA and Helm, B A BA.. (1993) Modeling of the lectin-homology domains of the human and murine low-affinity Fc epsilon receptor (Fc epsilon RII/CD23).. Receptor, [PMID:8142907] |
| 9. Bajorath, J J and Aruffo, A A.. (1996) Structure-based modeling of the ligand binding domain of the human cell surface receptor CD23 and comparison of two independently derived molecular models.. Protein science : a publication of the Protein Society, [PMID:8745401] |
| 10. Grimwood, Jane J and 97 more authors.. (2004) The DNA sequence and biology of human chromosome 19.. Nature, (1): [PMID:15057824] |
| 11. Hibbert, Richard G RG and 9 more authors.. (2005) The structure of human CD23 and its interactions with IgE and CD21.. The Journal of experimental medicine, (19): [PMID:16172256] |
| 12. Wurzburg, Beth A BA, Tarchevskaya, Svetlana S SS and Jardetzky, Theodore S TS.. (2006) Structural changes in the lectin domain of CD23, the low-affinity IgE receptor, upon calcium binding.. Structure (London, England : 1993), [PMID:16765898] |
| 13. Lemieux, George A GA and 9 more authors.. (2007) The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10.. The Journal of biological chemistry, (18): [PMID:17389606] |
| 14. Pathan, Nuzhat I NI and 5 more authors.. (2008) Mediation of apoptosis by and antitumor activity of lumiliximab in chronic lymphocytic leukemia cells and CD23+ lymphoma cell lines.. Blood, (1): [PMID:18032710] |
| 15. Ivaldi, Corinne C and 6 more authors.. (2012) Proteomic analysis of S-acylated proteins in human B cells reveals palmitoylation of the immune regulators CD20 and CD23.. PloS one, [PMID:22615937] |
| 16. Hersheson, Joshua J and 17 more authors.. (2013) Mutations in the autoregulatory domain of β-tubulin 4a cause hereditary dystonia.. Annals of neurology, [PMID:23424103] |
