| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab191658-10μg (Trial Size) Apply for free trial size（?） Every year, as a valued customer, you have the exclusive opportunity to explore and enjoy three different trial products of your choice, absolutely free! | 10μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $59.90 | |
| Ab191658-25μg | 25μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $109.90 | |
| Ab191658-100μg | 100μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $269.90 |
mAb (RA3-6B2); Rat anti Mouse/Human CD45R Antibody (AF405); Flow
| Product Name | CD45R Rat mAb (AF405) |
|---|---|
| Synonyms | LCA | CD45 | T200 | GP180 | IMD105 | B220 | CD45 antigen | CD45R | EC 3.1.3.48 | L-CA | LY5 | protein tyrosine phosphatase, receptor type, C | receptor-type tyrosine-protein phosphatase C | T200 glycoprotein | T200 leukocyte common antigen | T200receptor |
| Specifications & Purity | ExactAb™, Validated, Ex:401nm, Em:422nm, 0.5 mg/mL |
| Biochemical and Physiological Mechanisms | Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affec |
| Host species | Rat |
| Specificity | CD45R |
| Immunogen | Abelson murine leukemia virus-induced pre-B tumor cells |
| Positive Control | Flow: C57BL/6 mouse splenocytes. |
| Conjugation | Alexa Fluor® 405 |
| Grade | Em:422nm, Ex:401nm, ExactAb™, Validated |
| Product Description |
Rat anti Mouse/Human CD45R Antibody, Monoclonal (RA3-6B2), could be used for Flow.
|
| Isotype | Rat IgG2a |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 26.4 kDa (Light Chain) & 50.4 kDa (Heavy Chain), under reducing conditions; 207.1 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Concentration | 0.5 mg/mL |
| Storage Temp | Store at 2-8°C,Protected from light,Freeze prohibited |
| Shipped In | Wet ice |
| Stability And Storage | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
CD45R Rat mAb (AF405) (Ab191658) - Flow Cytometry
Flow cytometry analysis of CD45R expression by C57BL/6 mouse splenocytes (right panel) compared to an isotype control (left panel). Cells were stained with CD45R Rat mAb (AF405) (Ab191658) at 0.2μg/test for 1 hour at 4°C. Left panel - Rat IgG (AF405) (Ab190070).
CD45R Rat mAb (AF405) (Ab191658) - Flow Cytometry
Flow cytometry analysis of CD45R expression by C57BL/6 mouse splenocytes (red) compared to an isotype control (blue). Cells were stained with CD45R Rat mAb (AF405) (Ab191658) at 0.2μg/test for 1 hour at 4°C. Blue - Rat IgG (AF405) (Ab190070). Black - Unlabelled control, cells without incubation with primary antibody.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Application | Dilution info |
|---|---|
| Flow Cytometry |
≤1.0 μg/test,
the suggested use of this reagent is ≤1.0 μg per million cells in 100 µL staining volume
|
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