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CDK2-IN-73 (CDK2-IN-4) - 98%, high purity , CAS No.2079895-42-2
CDK2 Selective Inhibitors
Basic Description
| Specifications & Purity | ≥98% |
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| Biochemical and Physiological Mechanisms | CDK2-IN-73 (CDK2-IN-4, CDK2 inhibitor 73) is a potent and selective inhibitor of CDK2 with IC50 of 44 nM for CDK2/cyclin A. |
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| Storage Temp | Protected from light,Store at -20°C |
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| Shipped In | Ice chest + Ice pads |
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| Product Description | CDK2-IN-73 (CDK2-IN-4, CDK2 inhibitor 73) is a potent and selective inhibitor ofCDK2with IC50 of 44 nM for CDK2/cyclin A.
Targets Cdk2/cyclin A (Cell-free assay) 44 nM |
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Associated Targets(Human)
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | 4-[[6-(3-phenylphenyl)-7H-purin-2-yl]amino]benzenesulfonamide |
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| INCHI | InChI=1S/C23H18N6O2S/c24-32(30,31)19-11-9-18(10-12-19)27-23-28-20(21-22(29-23)26-14-25-21)17-8-4-7-16(13-17)15-5-2-1-3-6-15/h1-14H,(H2,24,30,31)(H2,25,26,27,28,29) |
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| InChi Key | FUGRWXRQJGJIER-UHFFFAOYSA-N |
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| Canonical SMILES | C1=CC=C(C=C1)C2=CC(=CC=C2)C3=C4C(=NC(=N3)NC5=CC=C(C=C5)S(=O)(=O)N)N=CN4 |
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| Isomeric SMILES | C1=CC=C(C=C1)C2=CC(=CC=C2)C3=C4C(=NC(=N3)NC5=CC=C(C=C5)S(=O)(=O)N)N=CN4 |
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| PubChem CID | 123132899 |
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| Molecular Weight | 442.49 |
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Chemical and Physical Properties
| Solubility | Solubility (25°C) In vitro DMSO: 88 mg/mL (198.87 mM); Water: Insoluble; Ethanol: Insoluble; |
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| Sensitivity | Moisture sensitive; Light sensitive |
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Safety and Hazards(GHS)
| Signal | Warning |
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| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
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| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. |
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