| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab092849-10μg | 10μg | In stock | $29.90 | |
| Ab092849-50μg | 50μg | In stock | $89.90 | |
| Ab092849-100μg | 100μg | In stock | $139.90 | |
| Ab092849-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,099.90 |
mAb (CB30); Mouse anti Human CEA/CD66e Antibody; Flow; Unconjugated
| Product Name | CEA/CD66e Mouse mAb - Primary antibody, specific to Carcino Embryonic Antigen CEA, Mouse IgG1 |
|---|---|
| Synonyms | Carcinoembryonic antigen | carcinoembryonic antigen-related cell adhesion molecule 5 | CD66e antigen | CD66e | CEA | CEACAM5 | CEACAM-5 | CEACD66e | DKFZp781M2392 | Meconium antigen 100 | Carcinoembryonic antigen antibody | Carcinoembryonic antigen-relate |
| Specifications & Purity | ExactAb™, Validated, Carrier Free, Azide Free, Lot by Lot |
| Host species | Mouse |
| Specificity | Carcino Embryonic Antigen CEA |
| Immunogen | CEACAM5 Protein |
| Conjugation | Unconjugated |
| Grade | Azide Free, Carrier Free, ExactAb™, Validated |
| Product Description |
Mouse anti Human CEA/CD66e Antibody, Monoclonal (CB30), could be used for Flow and so on. |
| Isotype | Mouse IgG1 |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Protein G purified |
| Form | Liquid |
| Concentration | Lot by Lot |
| Storage Temp | Store at 2-8°C |
| Shipped In | Wet ice |
| Stability And Storage | Shipped at 4°C. Store at 4°C long term (12 months). Upon delivery aliquot. |
CEA/CD66e Mouse mAb (Ab092849) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CEA/CD66e with CEA/CD66e Mouse mAb (Ab092849) (right panel) at 0.2 μg/mL for 1 hour at 4°C, compared with mouse IgG (Ab170221) - Isotype Control (left panel) and detected with Goat Anti-Mouse IgG H&L (PE) (Ab179006).
CEA/CD66e Mouse mAb (Ab092849) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CEA/CD66e (red) with CEA/CD66e Mouse mAb (Ab092849) at 0.2 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG H&L (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Application | Dilution info |
|---|---|
| Flow Cytometry | 1μg/100w cells "> 1μg/100w cells |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0202922 | Certificate of Analysis | Mar 01, 2024 | Ab092849 |
| ZJ24F0202900 | Certificate of Analysis | Mar 01, 2024 | Ab092849 |
| ZJ24F0202899 | Certificate of Analysis | Mar 01, 2024 | Ab092849 |
| 1. Hefta, L J LJ and 5 more authors.. (1990) Expression of complementary DNA and genomic clones for carcinoembryonic antigen and nonspecific cross-reacting antigen in Chinese hamster ovary and mouse fibroblast cells and characterization of the membrane-expressed products.. Cancer research, (15): [PMID:2317824] |
| 2. Schrewe, H H and 8 more authors.. (1990) Cloning of the complete gene for carcinoembryonic antigen: analysis of its promoter indicates a region conveying cell type-specific expression.. Molecular and cellular biology, [PMID:2342461] |
| 3. Oikawa, S S and 5 more authors.. (1989) Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: homophilic and heterophilic adhesion.. Biochemical and biophysical research communications, (16): [PMID:2803308] |
| 4. Zimmermann, W W, Ortlieb, B B, Friedrich, R R and von Kleist, S S.. (1987) Isolation and characterization of cDNA clones encoding the human carcinoembryonic antigen reveal a highly conserved repeating structure.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:3033671] |
| 5. Barnett, T T, Goebel, S J SJ, Nothdurft, M A MA and Elting, J J JJ.. (1988) Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains.. Genomics, [PMID:3220478] |
| 6. Beauchemin, N N, Benchimol, S S, Cournoyer, D D, Fuks, A A and Stanners, C P CP.. (1987) Isolation and characterization of full-length functional cDNA clones for human carcinoembryonic antigen.. Molecular and cellular biology, [PMID:3670312] |
| 7. Oikawa, S S, Nakazato, H H and Kosaki, G G.. (1987) Primary structure of human carcinoembryonic antigen (CEA) deduced from cDNA sequence.. Biochemical and biophysical research communications, (30): [PMID:3814146] |
| 8. Frängsmyr, L L, Baranov, V V and Hammarström, S S.. () Four carcinoembryonic antigen subfamily members, CEA, NCA, BGP and CGM2, selectively expressed in the normal human colonic epithelium, are integral components of the fuzzy coat.. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, [PMID:10436421] |
| 9. Boehm, M K MK and Perkins, S J SJ.. (2000) Structural models for carcinoembryonic antigen and its complex with the single-chain Fv antibody molecule MFE23.. FEBS letters, (9): [PMID:10854848] |
| 10. Taheri, M M and 5 more authors.. (2000) Self recognition in the Ig superfamily. Identification of precise subdomains in carcinoembryonic antigen required for intercellular adhesion.. The Journal of biological chemistry, (1): [PMID:10864933] |
| 11. Ordoñez, C C, Screaton, R A RA, Ilantzis, C C and Stanners, C P CP.. (2000) Human carcinoembryonic antigen functions as a general inhibitor of anoikis.. Cancer research, (1): [PMID:10910050] |
| 12. Grimwood, Jane J and 97 more authors.. (2004) The DNA sequence and biology of human chromosome 19.. Nature, (1): [PMID:15057824] |
| 13. Ramachandran, Prasanna P and 5 more authors.. (2006) Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.. Journal of proteome research, [PMID:16740002] |
| 14. Korotkova, Natalia N and 9 more authors.. (2008) Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation.. Molecular microbiology, [PMID:18086185] |
| 15. Govindan, Serengulam V SV, Cardillo, Thomas M TM, Moon, Sung-Ju SJ, Hansen, Hans J HJ and Goldenberg, David M DM.. (2009) CEACAM5-targeted therapy of human colonic and pancreatic cancer xenografts with potent labetuzumab-SN-38 immunoconjugates.. Clinical cancer research : an official journal of the American Association for Cancer Research, (1): [PMID:19789330] |
| 16. Bonsor, Daniel A DA, Günther, Sebastian S, Beadenkopf, Robert R, Beckett, Dorothy D and Sundberg, Eric J EJ.. (2015) Diverse oligomeric states of CEACAM IgV domains.. Proceedings of the National Academy of Sciences of the United States of America, (3): [PMID:26483485] |
