Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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C102193-50mg | 50mg | In stock | $9.90 | |
C102193-250mg | 250mg | In stock | $15.90 | |
C102193-1g | 1g | In stock | $21.90 | |
C102193-5g | 5g | In stock | $81.90 | |
C102193-25g | 25g | In stock | $251.90 | |
C102193-100g | 100g | In stock | $906.90 |
Third-generation cephalosporin antibiotic
Synonyms | CEFOTAXIME SODIUM | 64485-93-4 | Sodium cefotaxime | CEFOTAXIME SODIUM SALT | Pretor | Tolycar | HR 756 | Claforan | Ralopar | Tolycor | Zariviz | Claforan sodium | (+)-Cefotaxime sodium salt | RU 24756 | Cefotaxime sodium salt (syn-isomer) | HR-756 | Cefotaxime (sodium) | UNII-258J72S7TZ |
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Specifications & Purity | ≥99.5%(HPLC) |
Biochemical and Physiological Mechanisms | Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzy |
Storage Temp | Store at 2-8°C,Argon charged |
Shipped In | Wet ice |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Potent β-lactamase-resistant antibiotic of cephalosporin class. Active against Gram-positive and Gram-negative organisms, including Gram-negative anaerobes. Inhibits cell wall synthesis. |
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Pubchem Sid | 488196778 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488196778 |
IUPAC Name | sodium;(6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate |
INCHI | InChI=1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1 |
InChi Key | AZZMGZXNTDTSME-JUZDKLSSSA-M |
Canonical SMILES | CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)[O-].[Na+] |
Isomeric SMILES | CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\OC)/C3=CSC(=N3)N)SC1)C(=O)[O-].[Na+] |
WGK Germany | 2 |
RTECS | XI0250000 |
PubChem CID | 10695961 |
Molecular Weight | 477.45 |
Beilstein | 5711411 |
Reaxy-Rn | 6564218 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
F2320363 | Certificate of Analysis | Jun 29, 2023 | C102193 |
F2320372 | Certificate of Analysis | Jun 29, 2023 | C102193 |
F2320374 | Certificate of Analysis | Jun 29, 2023 | C102193 |
F2320375 | Certificate of Analysis | Jun 29, 2023 | C102193 |
F2320380 | Certificate of Analysis | Jun 29, 2023 | C102193 |
F2320385 | Certificate of Analysis | Jun 29, 2023 | C102193 |
F2320395 | Certificate of Analysis | Jun 29, 2023 | C102193 |
F2320403 | Certificate of Analysis | Jun 29, 2023 | C102193 |
F2320407 | Certificate of Analysis | Jun 29, 2023 | C102193 |
F2320414 | Certificate of Analysis | Jun 29, 2023 | C102193 |
F2320424 | Certificate of Analysis | Jun 29, 2023 | C102193 |
H2426269 | Certificate of Analysis | Jun 29, 2023 | C102193 |
E1803087 | Certificate of Analysis | Mar 30, 2022 | C102193 |
Solubility | Soluble in water. |
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Sensitivity | Light & moisture Heat sensitive |
Specific Rotation[α] | 61 ° (C=1, H2O) |
Melt Point(°C) | 163°C(dec.)(lit.) |
Pictogram(s) | GHS08, GHS07 |
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Signal | Danger |
Hazard Statements | H335:May cause respiratory irritation H317:May cause an allergic skin reaction H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P319:Get medical help if you feel unwell. P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately. |
WGK Germany | 2 |
RTECS | XI0250000 |
Reaxy-Rn | 6564218 |
Merck Index | 1933 |