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Ceftiofur HCl - ≥95%, high purity , CAS No.103980-44-5
Broad spectrum antibiotic agent. Irreversible PBP transpeptidase inhibitor.
Basic Description Synonyms 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((2-furanylcarbonyl)thio)methyl)-8-oxo, monohydrochloride, (6R,7R) | Ceftiofur, HCl | Spectramast LC Sterile Suspension | DTXSID101034300 | Specifications & Purity ≥95% Biochemical and Physiological Mechanisms Ceftiofur Hydrochloride is a cephalosporin antibiotic. The compound is a derivative of a third generation cephalosporin, Ceftiofur. Ceftiofur has been used in bovine studies and in antibiotic resistancy studies of Escherichia coli and Salmonella enterica. Storage Temp Store at 2-8°C Shipped In Wet ice Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. Product Description Ceftiofur HCl is a hydrochloride of ceftiofur that is a broad spectrum cephalosporin.
Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers Pubchem Sid 488196449 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488196449 IUPAC Name (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride INCHI InChI=1S/C19H17N5O7S3.ClH/c1-30-23-11(9-7-34-19(20)21-9)14(25)22-12-15(26)24-13(17(27)28)8(5-32-16(12)24)6-33-18(29)10-3-2-4-31-10;/h2-4,7,12,16H,5-6H2,1H3,(H2,20,21)(H,22,25)(H,27,28);1H/b23-11-;/t12-,16-;/m1./s1 InChi Key KEQFDTJEEQKVLM-JUODUXDSSA-N Canonical SMILES CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)CSC(=O)C4=CC=CO4)C(=O)O.Cl Isomeric SMILES CO/N=C(/C1=CSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)CSC(=O)C4=CC=CO4)C(=O)O.Cl PubChem CID 9937686 Molecular Weight 560.02
Chemical and Physical Properties Solubility Soluble in methanol, water (<1 mg/ml at 25 °C), DMSO (112 mg/ml at 25 °C), and ethanol (40 mg/ml at 25 °C).
Safety and Hazards(GHS) Pictogram(s) GHS08 , GHS07 Signal Danger Hazard Statements H373: Causes damage to organs through prolonged or repeated exposure
H317: May cause an allergic skin reaction
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P501: Dispose of contents/container to ...
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P284: [In case of inadequate ventilation] Wear respiratory protection.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P272: Contaminated work clothing should not be allowed out of the workplace.
P333+P313: IF SKIN irritation or rash occurs: Get medical advice/attention.
P362+P364: Take off contaminated clothing and wash it before reuse.
P319: Get medical help if you feel unwell.
P342+P316: If experiencing respiratory symptoms: Get emergence medical help immediately.
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