Ceftizoxime sodium - 95%, high purity , Bacterial penicillin-binding protein inhibitor, CAS No.68401-82-1, Bacterial penicillin-binding protein inhibitor

  • ≥95%
Item Number
C348063
Grouped product items
SKUSizeAvailabilityPrice Qty
C348063-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$38.90
C348063-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$161.90
C348063-100mg
100mg
In stock
$290.90
C348063-250mg
250mg
In stock
$652.90
C348063-1g
1g
In stock
$2,350.90
C348063-5g
5g
In stock
$10,576.90

Basic Description

SynonymsSR-01000872666-1 | CEFTIZOXIME SODIUM [VANDF] | Epocelin (TN) | Monosodium Salt, Ceftizoxime | Cefizox | CEFTIZOXIME SODIUM [JAN] | SKF-88373 | 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)-(methoxyimino)acetyl)amino)-8-
Specifications & Purity≥95%
Biochemical and Physiological MechanismsCeftizoxime is third generation cephalosporin effective against Gram-negative and Gram-positive bacteria. It binds penicillin-binding proteins (PBPs) and inhibits the bacterial cell wall synthesis.
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
Action TypeINHIBITOR
Mechanism of actionBacterial penicillin-binding protein inhibitor
Product Description

Product description:

Ceftizoxime, a third-generation cephalosporin effective against Gram-negative and Gram-positive bacteria, binds penicillin-binding proteins (PBPs) to inhibit the bacterial cell wall synthesis. It rather resembles cefotaxime in its properties but is not subject to metabolism.


Application:

A broad spectrum antibiotic targeting a wide variety of Gram-positive and Gram-negative bacteria;

Associated Targets(non-human)

Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus epidermidis (22802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterococcus faecalis (29875 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488200392
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488200392
IUPAC Name sodium;(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
INCHI InChI=1S/C13H13N5O5S2.Na/c1-23-17-7(5-4-25-13(14)15-5)9(19)16-8-10(20)18-6(12(21)22)2-3-24-11(8)18;/h2,4,8,11H,3H2,1H3,(H2,14,15)(H,16,19)(H,21,22);/q;+1/p-1/b17-7-;/t8-,11-;/m1./s1
InChi Key ADLFUPFRVXCDMO-LIGXYSTNSA-M
Canonical SMILES CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=CCS3)C(=O)[O-].[Na+]
Isomeric SMILES CO/N=C(/C1=CSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=CCS3)C(=O)[O-].[Na+]
PubChem CID 23663938
Molecular Weight 405.39

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

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8 results found

Lot NumberCertificate TypeDateItem
E2324610Certificate of AnalysisApr 21, 2023 C348063
E2324611Certificate of AnalysisApr 21, 2023 C348063
E2324612Certificate of AnalysisApr 21, 2023 C348063
E2324614Certificate of AnalysisApr 21, 2023 C348063
E2324615Certificate of AnalysisApr 21, 2023 C348063
E2324617Certificate of AnalysisApr 21, 2023 C348063
E2324642Certificate of AnalysisApr 21, 2023 C348063
E2324654Certificate of AnalysisApr 21, 2023 C348063

Chemical and Physical Properties

SolubilitySoluble in water
SensitivityMoisture sensitive

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

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