Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C304513-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $309.90 | |
C304513-500mg | 500mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,030.90 | |
C304513-1g | 1g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,648.90 | |
C304513-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $3,090.90 |
Synonyms | 7-[2-(2-Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-3-(6-hydroxy-2-methyl-5-oxo-2,5-dihydro-[1,2,4]triazin-3-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid (Ceftriaxone) | J01DA13 | C06683 | DTXSID0022773 | 5-Thia-1-aza |
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Specifications & Purity | Moligand™, ≥95% |
Storage Temp | Protected from light,Store at -20°C,Argon charged |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(2-methyl-5,6-dioxo-1H-1,2,4-triazin-3-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
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INCHI | InChI=1S/C18H18N8O7S3/c1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7/h5,9,15H,3-4H2,1-2H3,(H2,19,20)(H,21,27)(H,23,29)(H,31,32)/b24-8-/t9-,15-/m1/s1 |
InChi Key | VAAUVRVFOQPIGI-SPQHTLEESA-N |
Canonical SMILES | CN1C(=NC(=O)C(=O)N1)SCC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)O |
Isomeric SMILES | CN1C(=NC(=O)C(=O)N1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)/C(=N\OC)/C4=CSC(=N4)N)SC2)C(=O)O |
PubChem CID | 5479530 |
Molecular Weight | 554.58 |
Wikipedia | Ceftriaxone |
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CAS Registry No. | 73384-59-5 |
DrugBank Ligand | DB01212 |
PubChem CID | 5479530 |
ChEMBL Ligand | CHEMBL161 |
DrugCentral Ligand | 564 |
Antibiotic DB | 1914 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
G2412050 | Certificate of Analysis | Aug 08, 2023 | C304513 |
I2315160 | Certificate of Analysis | Aug 08, 2023 | C304513 |
I2315161 | Certificate of Analysis | Aug 08, 2023 | C304513 |
I2315162 | Certificate of Analysis | Aug 08, 2023 | C304513 |
I2315163 | Certificate of Analysis | Aug 08, 2023 | C304513 |
L2403082 | Certificate of Analysis | Aug 08, 2023 | C304513 |
Solubility | DMSO (Slightly), Methanol (Slightly) |
---|---|
Sensitivity | light sensitive;Moisture sensitive |
Melt Point(°C) | >189°C |
Pictogram(s) | GHS08, GHS07 |
---|---|
Signal | Danger |
Hazard Statements | H317:May cause an allergic skin reaction H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P284:[In case of inadequate ventilation] Wear respiratory protection. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately. |
Starting at $16.90
Starting at $35.90
1. Yangfa Chao, Wenting Huang, Zhiheng Xu, Ping Li, Shaodong Gu. (2023) Effect of RUNX1/FOXP3 axis on apoptosis of T and B lymphocytes and immunosuppression in sepsis. Open Medicine, 18 (1): [PMID:37636994] |
2. Yexuan Mao, Yichao Fan, Ran Yang, Youyi Wang, Qingyue Li, Meng Dang, Xianqing Huang, Lianjun Song, Pingan Zhang, Miao Song, Liang Liu, Linli Wang, Shun Yu, Qiuyan Zhao, Xiya Zhang. (2023) A highly sensitive electrochemical sensor derived from peptide amphiphilic inspired self-assembled, ordered gold nanoparticles for determination of 22 β-lactams. ELECTROCHIMICA ACTA, 461 (142669). [PMID:] |
3. Junyu Qian, Haotian Qin, Peijie Zeng, Jiaming Hou, Xiaoshan Mo, Gang Shen, Hui Zeng, Wentai Zhang, Yingqi Chen, Guojiang Wan. (2023) Metal-organic Zn-zoledronic acid and 1-hydroxyethylidene-1,1-diphosphonic acid nanostick-mediated zinc phosphate hybrid coating on biodegradable Zn for osteoporotic fracture healing implants. Acta Biomaterialia, [PMID:37196904] |
4. Lishan Zhang, Zujie Yao, Huamei Tang, Qingli Song, Huanhuan Song, Jindong Yao, Zhen Li, Xiaofang Xie, Yuexu Lin, Xiangmin Lin. (2022) The Lysine Acetylation Modification in the Porin Aha1 of Aeromonas hydrophila Regulates the Uptake of Multidrug Antibiotics. MOLECULAR & CELLULAR PROTEOMICS, 21 (9): [PMID:35605723] |
5. Shuangmin Wu, Wei Shen, Yushuang Chen, Yongli Zhu, Ren Hou, Menghong Dai, Dapeng Peng. (2022) Rapid Determination of Cephalexin in Animal-Derived Food by an Indirect Competitive Enzyme-Linked Immunosorbent Assay. ANALYTICAL LETTERS, 55 (17): (2803-2816). [PMID:] |
6. Miao Z. H., Zhou W. X., Cheng R. Y., Liang H. J., Jiang F. L., Shen X., Lu J. H., Li M., He F.. (2021) Dysbiosis of intestinal microbiota in early life aggravates high-fat diet induced dysmetabolism in adult mice. BMC MICROBIOLOGY, 21 (1): (1-12). [PMID:34238228] |
7. Ruyue Cheng, Jiawen Guo, Yujie Zhang, Guo Cheng, Wei Qian, ChaoMin Wan, Ming Li, Francesco Marotta, Xi Shen, Fang He. (2021) Impacts of ceftriaxone exposure during pregnancy on maternal gut and placental microbiota and its influence on maternal and offspring immunity in mice. EXPERIMENTAL ANIMALS, [PMID:33268669] |
8. Yanan Cai, Jing He, Jinkang Zhang, Jicheng Li. (2020) Antibiotic contamination control mediated by manganese oxidizing bacteria in a lab-scale biofilter. Journal of Environmental Sciences, 98 (47). [PMID:33097157] |
9. Miao Zhonghua, Cheng Ruyue, Zhang Yujie, Liang Huijing, Jiang Fengling, Shen Xi, Chen Gong, Zhang Qisheng, He Fang, Li Ming. (2020) Antibiotics can cause weight loss by impairing gut microbiota in mice and the potent benefits of lactobacilli. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 84 (2): (411-420). [PMID:31661358] |
10. Chen Lili, Xu Hui, Wang Li, Li Yong, Tian Xike. (2020) Portable ratiometric probe based on the use of europium(III) coordination polymers doped with carbon dots for visual fluorometric determination of oxytetracycline. MICROCHIMICA ACTA, 187 (2): (1-8). [PMID:31938900] |
11. Yunlei Zhou, Fei Li, Hanwen Wu, Yan Chen, Huanshun Yin, Shiyun Ai, Jun Wang. (2019) Electrochemical aptasensing strategy for kanamycin detection based on target-triggered single-strand DNA adsorption on MoS2 nanosheets and enzymatic signal amplification. SENSORS AND ACTUATORS B-CHEMICAL, 296 (126664). [PMID:] |
12. Cheng RuYue, Guo JiaWen, Pu FangFang, Wan ChaoMin, Shi Lei, Li HuaWen, Yang YuHong, Huang ChengYu, Li Ming, He Fang. (2019) Loading ceftriaxone, vancomycin, and Bifidobacteria bifidum TMC3115 to neonatal mice could differently and consequently affect intestinal microbiota and immunity in adulthood. Scientific Reports, 9 (1): (1-15). [PMID:30824845] |
13. Tingting Fang, Hui Wang, Qijia Cui, Matt Rogers, Peiyan Dong. (2018) Diversity of potential antibiotic-resistant bacterial pathogens and the effect of suspended particles on the spread of antibiotic resistance in urban recreational water. WATER RESEARCH, 145 (541). [PMID:30199799] |
1. Yangfa Chao, Wenting Huang, Zhiheng Xu, Ping Li, Shaodong Gu. (2023) Effect of RUNX1/FOXP3 axis on apoptosis of T and B lymphocytes and immunosuppression in sepsis. Open Medicine, 18 (1): [PMID:37636994] |
2. Yexuan Mao, Yichao Fan, Ran Yang, Youyi Wang, Qingyue Li, Meng Dang, Xianqing Huang, Lianjun Song, Pingan Zhang, Miao Song, Liang Liu, Linli Wang, Shun Yu, Qiuyan Zhao, Xiya Zhang. (2023) A highly sensitive electrochemical sensor derived from peptide amphiphilic inspired self-assembled, ordered gold nanoparticles for determination of 22 β-lactams. ELECTROCHIMICA ACTA, 461 (142669). [PMID:] |
3. Junyu Qian, Haotian Qin, Peijie Zeng, Jiaming Hou, Xiaoshan Mo, Gang Shen, Hui Zeng, Wentai Zhang, Yingqi Chen, Guojiang Wan. (2023) Metal-organic Zn-zoledronic acid and 1-hydroxyethylidene-1,1-diphosphonic acid nanostick-mediated zinc phosphate hybrid coating on biodegradable Zn for osteoporotic fracture healing implants. Acta Biomaterialia, [PMID:37196904] |
4. Lishan Zhang, Zujie Yao, Huamei Tang, Qingli Song, Huanhuan Song, Jindong Yao, Zhen Li, Xiaofang Xie, Yuexu Lin, Xiangmin Lin. (2022) The Lysine Acetylation Modification in the Porin Aha1 of Aeromonas hydrophila Regulates the Uptake of Multidrug Antibiotics. MOLECULAR & CELLULAR PROTEOMICS, 21 (9): [PMID:35605723] |
5. Shuangmin Wu, Wei Shen, Yushuang Chen, Yongli Zhu, Ren Hou, Menghong Dai, Dapeng Peng. (2022) Rapid Determination of Cephalexin in Animal-Derived Food by an Indirect Competitive Enzyme-Linked Immunosorbent Assay. ANALYTICAL LETTERS, 55 (17): (2803-2816). [PMID:] |
6. Miao Z. H., Zhou W. X., Cheng R. Y., Liang H. J., Jiang F. L., Shen X., Lu J. H., Li M., He F.. (2021) Dysbiosis of intestinal microbiota in early life aggravates high-fat diet induced dysmetabolism in adult mice. BMC MICROBIOLOGY, 21 (1): (1-12). [PMID:34238228] |
7. Ruyue Cheng, Jiawen Guo, Yujie Zhang, Guo Cheng, Wei Qian, ChaoMin Wan, Ming Li, Francesco Marotta, Xi Shen, Fang He. (2021) Impacts of ceftriaxone exposure during pregnancy on maternal gut and placental microbiota and its influence on maternal and offspring immunity in mice. EXPERIMENTAL ANIMALS, [PMID:33268669] |
8. Yanan Cai, Jing He, Jinkang Zhang, Jicheng Li. (2020) Antibiotic contamination control mediated by manganese oxidizing bacteria in a lab-scale biofilter. Journal of Environmental Sciences, 98 (47). [PMID:33097157] |
9. Miao Zhonghua, Cheng Ruyue, Zhang Yujie, Liang Huijing, Jiang Fengling, Shen Xi, Chen Gong, Zhang Qisheng, He Fang, Li Ming. (2020) Antibiotics can cause weight loss by impairing gut microbiota in mice and the potent benefits of lactobacilli. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 84 (2): (411-420). [PMID:31661358] |
10. Chen Lili, Xu Hui, Wang Li, Li Yong, Tian Xike. (2020) Portable ratiometric probe based on the use of europium(III) coordination polymers doped with carbon dots for visual fluorometric determination of oxytetracycline. MICROCHIMICA ACTA, 187 (2): (1-8). [PMID:31938900] |
11. Yunlei Zhou, Fei Li, Hanwen Wu, Yan Chen, Huanshun Yin, Shiyun Ai, Jun Wang. (2019) Electrochemical aptasensing strategy for kanamycin detection based on target-triggered single-strand DNA adsorption on MoS2 nanosheets and enzymatic signal amplification. SENSORS AND ACTUATORS B-CHEMICAL, 296 (126664). [PMID:] |
12. Cheng RuYue, Guo JiaWen, Pu FangFang, Wan ChaoMin, Shi Lei, Li HuaWen, Yang YuHong, Huang ChengYu, Li Ming, He Fang. (2019) Loading ceftriaxone, vancomycin, and Bifidobacteria bifidum TMC3115 to neonatal mice could differently and consequently affect intestinal microbiota and immunity in adulthood. Scientific Reports, 9 (1): (1-15). [PMID:30824845] |
13. Tingting Fang, Hui Wang, Qijia Cui, Matt Rogers, Peiyan Dong. (2018) Diversity of potential antibiotic-resistant bacterial pathogens and the effect of suspended particles on the spread of antibiotic resistance in urban recreational water. WATER RESEARCH, 145 (541). [PMID:30199799] |