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CEP-18770 (Delanzomib) - 10mM in DMSO, high purity , CAS No.847499-27-8
Basic Description Synonyms Delanzomib|847499-27-8|CEP-18770|CEP 18770|CT-47098|Delanzomib (CEP-18770)|NPH007098|((R)-1-((2S,3R)-3-Hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutyl)boronic acid|NPH 007098|Delanzomib [USAN:INN]|UNII-6IF28942WO|Delanzomib [USAN]|6IF28942WO|CHE Specifications & Purity 10mM in DMSO Biochemical and Physiological Mechanisms CEP-18770 is a novel orally-active inhibitor of the chymotrypsin-like activity of the proteasome that down-modulates the nuclear factor-kappaB (NF-kappaB) activity and the expression of several NF-kappaB downstream effectors.
in vitro: CEP-18770 and borte Storage Temp Store at -80°C Shipped In Ice chest + Ice pads
Names and Identifiers IUPAC Name [(1R)-1-[[(2S,3R)-3-hydroxy-2-[(6-phenylpyridine-2-carbonyl)amino]butanoyl]amino]-3-methylbutyl]boronic acid INCHI InChI=1S/C21H28BN3O5/c1-13(2)12-18(22(29)30)24-21(28)19(14(3)26)25-20(27)17-11-7-10-16(23-17)15-8-5-4-6-9-15/h4-11,13-14,18-19,26,29-30H,12H2,1-3H3,(H,24,28)(H,25,27)/t14-,18+,19+/m1/s1 InChi Key SJFBTAPEPRWNKH-CCKFTAQKSA-N Canonical SMILES B(C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C1=CC=CC(=N1)C2=CC=CC=C2)(O)O Isomeric SMILES B([C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)C1=CC=CC(=N1)C2=CC=CC=C2)(O)O PubChem CID 24800541 Molecular Weight 413.28
Chemical and Physical Properties Sensitivity Moisture sensitive Melt Point(°C) 178-190°C (dec.)
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