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Cerestat - ≥98%(HPLC), high purity , CAS No.137160-11-3

  • ≥98%(HPLC)
Item Number
C287458
Grouped product items
SKUSizeAvailabilityPrice Qty
C287458-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
C287458-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
C287458-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$399.90
C287458-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$719.90
C287458-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,289.90

Potent and noncompetitive NMDA antagonist

Basic Description

SynonymsCNS-1102|Aptiganel hydrochloride|N-(3-Ethylphenyl)-N-methyl-N'-1-naphthalenylguanidine hydrochloride
Specifications & Purity≥98%(HPLC)
Biochemical and Physiological MechanismsPotent and noncompetitive NMDA receptor antagonist (IC50= 36 nM). Exhibits >70-fold selectivity for NMDA receptor overσreceptor. Neuroprotective in a rat model of focal ischemia.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads

Associated Targets

GMNN Tbio Geminin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

FTL Tbio Ferritin light chain 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KMT2A Tchem Histone-lysine N-methyltransferase 2A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TXNRD1 Tclin Thioredoxin reductase 1, cytoplasmic 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SIGMAR1 Tclin Sigma non-opioid intracellular receptor 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PMP22 Tbio Peripheral myelin protein 22 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

LMNA Tbio Prelamin-A/C 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAPT Tclin Microtubule-associated protein tau 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

IMPA1 Tclin Inositol monophosphatase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GLS Tchem Glutaminase kidney isoform, mitochondrial 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRIN3A Tclin Glutamate receptor ionotropic, NMDA 3A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 1-(3-ethylphenyl)-1-methyl-2-naphthalen-1-ylguanidine;hydrochloride
INCHI InChI=1S/C20H21N3.ClH/c1-3-15-8-6-11-17(14-15)23(2)20(21)22-19-13-7-10-16-9-4-5-12-18(16)19;/h4-14H,3H2,1-2H3,(H2,21,22);1H
InChi Key CKAKVKWRMCAYJD-UHFFFAOYSA-N
Canonical SMILES CCC1=CC(=CC=C1)N(C)C(=NC2=CC=CC3=CC=CC=C32)N.Cl
Isomeric SMILES CCC1=CC(=CC=C1)N(C)C(=NC2=CC=CC3=CC=CC=C32)N.Cl
PubChem CID 60839
Molecular Weight 339.86

Certificates

Certificate of Analysis(COA)

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10 results found

Lot NumberCertificate TypeDateItem
G2418071Certificate of AnalysisApr 11, 2024 C287458
G2418072Certificate of AnalysisApr 11, 2024 C287458
G2418074Certificate of AnalysisApr 11, 2024 C287458
G2418076Certificate of AnalysisApr 11, 2024 C287458
G2418078Certificate of AnalysisApr 11, 2024 C287458
G2418080Certificate of AnalysisApr 11, 2024 C287458
G2418081Certificate of AnalysisApr 11, 2024 C287458
G2418082Certificate of AnalysisApr 11, 2024 C287458
G2418083Certificate of AnalysisApr 11, 2024 C287458
G2418084Certificate of AnalysisApr 11, 2024 C287458

Chemical and Physical Properties

SolubilitySolvent:water, Max Conc. mg/mL: 16.99, Max Conc. mM: 50; Solvent:DMSO, Max Conc. mg/mL: 33.99, Max Conc. mM: 100

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Solution Calculators