Cervonic Acid - 10mM in DMSO, high purity , CAS No.6217-54-5

Item Number

C425151

• Synonyms: Docosahexaenoic acid|Doconexent|Cervonic acid|6217-54-5|cis-4,7,10,13,16,19-Docosahexaenoic acid|Docosahexaenoate|Doconexentum|Doconexento|Doxonexent|all-cis-DHA|AquaGrow Advantage|Martek DHA HM|Ropufa 60|(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hex
• Specifications & Purity: Moligand™, 10mM in DMSO
• Biochemical and Physiological Mechanisms: Endogenous omega-3 fatty acid. Acts as a selective retinoid X receptor (RXR) agonist that displays no activity at RAR, thyroid hormone receptor or the vitamin D receptor (VDR). Activates all three RXR isoforms. Also shown to inhibit Aβ1-42 fibrillation an
• Storage Temp: Store at -80°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™

Product Description

DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total PUFA pool in retinal and neuronal membranes. Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa. Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.
Docosahexaenoic acid, DHA, is an omega-3 polyunsaturated fatty acid with 22 carbons and six double bonds, the first double bond occuring at position three from the methyl terminus (22:6 n-3). DHA is a component of lipid membranes and the myelin sheath. DHA also serves as a precursor for signaling molecules such as prostaglandins and eicosanoids.