CGP 42112 TFA - ≥98%, high purity , CAS No.127060-75-7(free base), Agonist of AT 2 receptor

Item Number

C276071

• Synonyms: CS-3414 | AKOS024457173 | N-(3-PYRIDINYLCARBONYL)-L-TYROSYL-N6-(N2-((PHENYLMETHOXY)CARBONYL)-L-ARGINYL)-L-LYSYL-L-HISTIDYL-L-PROLYL-L-ISOLEUCINE | UNII-9Q3V7W3XDD | (2S,3S)-2-[[(2S)-1-[(2S)-2-[[(2S)-6-[[(2S)-5-(diaminomethylideneamino)-2-(phenylmethoxycar
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Potent, selective AT 2 receptor ligand (K i = 0.24 nM). Shows agonist effects at proximal tubule AT 2 receptors. Inhibits Na + , K + -ATPase. Inhibits Angiotensin-II induced aortic contraction (IC 50 = 1.9 μM). Induces sodium excretion in vivo.
• Storage Temp: Store at -20°C,Desiccated
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: AGONIST
• Mechanism of action: Agonist of AT 2 receptor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

CGP-42112 TFA is A potent angiotensin receptor AT2 agonist that inhibits the increase in the activity of LPS-produced protein kinase A