CGP 71683 hydrochloride - ≥99%(HPLC), high purity , CAS No.192322-50-2

  • ≥99%(HPLC)
Item Number
C286617
Grouped product items
SKUSizeAvailabilityPrice Qty
C286617-2mg
2mg
In stock
$62.90
C286617-5mg
5mg
In stock
$129.90
C286617-10mg
10mg
In stock
$195.90
C286617-25mg
25mg
In stock
$441.90
C286617-50mg
50mg
In stock
$783.90
C286617-100mg
100mg
In stock
$1,360.90

Highly selective and potent non-peptide NPY Y5receptor antagonist

Basic Description

SynonymsAKOS024456984 | CGP 71683A; CGP71683A; CGP-71683 HCl | Q27258822 | MFCD00048633 | cgp71683a hcl | CGP-71683A HCl | N-[[4-[[(4-aminoquinazolin-2-yl)amino]methyl]cyclohexyl]methyl]naphthalene-1-sulfonamide;hydrochloride | SCHEMBL28512 | 45B73P82A3 | N-(((1r
Specifications & Purity≥99%(HPLC)
Biochemical and Physiological MechanismsExtremely selective, non-peptide NPY Y5receptor antagonist. Displays > 1000-fold selectivity over Y1, Y2and Y4receptors; IC50values are 1.4, 2765, 7187 and 5637 nM at cloned rat Y5, Y1, Y2and Y4receptors respectively. Potently inhibits NPY-induced food in
Storage TempStore at 2-8°C,Desiccated
Shipped InWet ice

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488196361
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488196361
IUPAC Name N-[[4-[[(4-aminoquinazolin-2-yl)amino]methyl]cyclohexyl]methyl]naphthalene-1-sulfonamide;hydrochloride
INCHI InChI=1S/C26H29N5O2S.ClH/c27-25-22-9-3-4-10-23(22)30-26(31-25)28-16-18-12-14-19(15-13-18)17-29-34(32,33)24-11-5-7-20-6-1-2-8-21(20)24;/h1-11,18-19,29H,12-17H2,(H3,27,28,30,31);1H
InChi Key DIQDKUNCSVFGHH-UHFFFAOYSA-N
Canonical SMILES C1CC(CCC1CNC2=NC3=CC=CC=C3C(=N2)N)CNS(=O)(=O)C4=CC=CC5=CC=CC=C54.Cl
Isomeric SMILES C1CC(CCC1CNC2=NC3=CC=CC=C3C(=N2)N)CNS(=O)(=O)C4=CC=CC5=CC=CC=C54.Cl
PubChem CID 9849276
Molecular Weight 512.07

Certificates

Certificate of Analysis(COA)

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12 results found

Lot NumberCertificate TypeDateItem
E23161260Certificate of AnalysisMar 30, 2023 C286617
E2316376Certificate of AnalysisMar 30, 2023 C286617
E2316381Certificate of AnalysisMar 30, 2023 C286617
E2316385Certificate of AnalysisMar 30, 2023 C286617
E2316396Certificate of AnalysisMar 30, 2023 C286617
E2316402Certificate of AnalysisMar 30, 2023 C286617
E2316403Certificate of AnalysisMar 30, 2023 C286617
E2316404Certificate of AnalysisMar 30, 2023 C286617
E2316408Certificate of AnalysisMar 30, 2023 C286617
E2316409Certificate of AnalysisMar 30, 2023 C286617
E2316410Certificate of AnalysisMar 30, 2023 C286617
E2316412Certificate of AnalysisMar 30, 2023 C286617

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Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 51.21, Max Conc. mM: 100

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