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CGS 19755 , CAS No.110347-85-8, Antagonist of GluN2A;Antagonist of GluN2B;Antagonist of GluN2C;Antagonist of GluN2D

Moligand™

CAS#: 110347-85-8
Formula: C₇H₁₄NO₅P
Molecular Weight: 223.17
PubChem CID: 68736

Item Number

C287470

Grouped product items
SKU	Size	Availability	Price	Qty
C287470-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$154.90
C287470-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$650.90

Potent competitive NMDA antagonist

View related series

GluN2A Antagonist GluN2B Antagonist GluN2C Antagonist GluN2D Antagonist

Basic Description

Synonyms	Selfotel\|110347-85-8\|CGS 19755\|(2S,4R)-4-(phosphonomethyl)piperidine-2-carboxylic acid\|CGS-19755\|Selfotel, (+)-\|CPDD 0027\|2-Piperidinecarboxylic acid, 4-(phosphonomethyl)-, cis-\|CGS-20282\|2-Piperidinecarboxylic acid, 4-(phosphonomethyl)-, (2S,4R)-\|GNF-Pf-
Specifications & Purity	Moligand™
Biochemical and Physiological Mechanisms	Potent, competitive NMDA receptor antagonist. Anticonvulsant and neuroprotective.
Storage Temp	Room temperature
Shipped In	Normal
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of GluN2A;Antagonist of GluN2B;Antagonist of GluN2C;Antagonist of GluN2D

Associated Targets

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Discover Target: TDP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIA3 Tclin Glutamate receptor 3 0 Activities

Discover Target: GRIA3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIK3 Tclin Glutamate receptor ionotropic, kainate 3 0 Activities

Discover Target: GRIK3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIA1 Tclin Glutamate receptor 1 0 Activities

Discover Target: GRIA1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIN3A Tclin Glutamate receptor ionotropic, NMDA 3A 0 Activities

Discover Target: GRIN3A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIN1 Tclin Glutamate receptor ionotropic, NMDA 1 0 Activities

Discover Target: GRIN1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIN2A Tclin Glutamate receptor ionotropic, NMDA 2A 0 Activities

Discover Target: GRIN2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIN2B Tclin Glutamate receptor ionotropic, NMDA 2B 0 Activities

Discover Target: GRIN2B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIN2C Tclin Glutamate receptor ionotropic, NMDA 2C 0 Activities

Discover Target: GRIN2C

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIN2D Tclin Glutamate receptor ionotropic, NMDA 2D 0 Activities

Discover Target: GRIN2D

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(2S,4R)-4-(phosphonomethyl)piperidine-2-carboxylic acid
INCHI	InChI=1S/C7H14NO5P/c9-7(10)6-3-5(1-2-8-6)4-14(11,12)13/h5-6,8H,1-4H2,(H,9,10)(H2,11,12,13)/t5-,6+/m1/s1
InChi Key	LPMRCCNDNGONCD-RITPCOANSA-N
Canonical SMILES	C1CNC(CC1CP(=O)(O)O)C(=O)O
Isomeric SMILES	C1CN[C@@H](C[C@@H]1CP(=O)(O)O)C(=O)O
PubChem CID	68736
Molecular Weight	223.17

Wikipedia

PubChem CID

CAS Registry No.

ChEMBL Ligand

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