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CGS 19755 , CAS No.110347-85-8, Antagonist of GluN2A;Antagonist of GluN2B;Antagonist of GluN2C;Antagonist of GluN2D
Potent competitive NMDA antagonist
Basic Description
| Synonyms | AKOS015914119 | 2-Piperidinecarboxylic acid, 4-(phosphonomethyl)-, (2R,4S)- | 4VGJ4A41L2 | CAS-110347-85-8 | N0905W44Y3 | SCHEMBL120234 | 4-Phosphonomethyl-piperidine-2-carboxylic acid | CGS19755 | CGS-19755 | 4-Phosphonomethyl-piperidine-2-carboxylic aci |
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| Specifications & Purity | Moligand™ |
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| Biochemical and Physiological Mechanisms | Potent, competitive NMDA receptor antagonist. Anticonvulsant and neuroprotective. |
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| Storage Temp | Room temperature |
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| Shipped In | Normal |
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| Grade | Moligand™ |
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| Action Type | ANTAGONIST |
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| Mechanism of action | Antagonist of GluN2A;Antagonist of GluN2B;Antagonist of GluN2C;Antagonist of GluN2D |
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Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | (2S,4R)-4-(phosphonomethyl)piperidine-2-carboxylic acid |
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| INCHI | InChI=1S/C7H14NO5P/c9-7(10)6-3-5(1-2-8-6)4-14(11,12)13/h5-6,8H,1-4H2,(H,9,10)(H2,11,12,13)/t5-,6+/m1/s1 |
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| InChi Key | LPMRCCNDNGONCD-RITPCOANSA-N |
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| Canonical SMILES | C1CNC(CC1CP(=O)(O)O)C(=O)O |
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| Isomeric SMILES | C1CN[C@@H](C[C@@H]1CP(=O)(O)O)C(=O)O |
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| PubChem CID | 68736 |
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| Molecular Weight | 223.17 |
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Chemical and Physical Properties
| Solubility | Solvent:water, Max Conc. mg/mL: 5.58, Max Conc. mM: 25 |
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