| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| C104903-20mg | 20mg | In stock | $69.90 |
| Synonyms | chenodeoxycholic acid|Chenodiol|474-25-9|Chenix|Chenic acid|Cdca|Chenodesoxycholic acid|Chenodeoxycholate|Gallodesoxycholic acid|Chendol|Anthropodeoxycholic acid|Anthropodesoxycholic acid|Anthropododesoxycholic acid|Chenofalk|Chenodesoxycholsaeure|Chenoco |
|---|---|
| Specifications & Purity | Moligand™, analytical standard |
| Biochemical and Physiological Mechanisms | Chenodeoxycholic Acid (CDCA), is a hydrophobic primary bile acid that activates nuclear receptors involved in cholesterol metabolism. Bile acids are essential for solubilization and transport of dietary lipids, are the major products of c |
| Storage Temp | Protected from light |
| Shipped In | Normal |
| Grade | analytical standard, Moligand™ |
| Action Type | AGONIST, ANTAGONIST |
| Mechanism of action | Agonist of Farnesoid X receptor;Antagonist of FPR1;Agonist of GPBA receptor |
| ALogP | 4.9 |
|---|
| IUPAC Name | (4R)-4-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid |
|---|---|
| INCHI | InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1 |
| InChi Key | RUDATBOHQWOJDD-BSWAIDMHSA-N |
| Canonical SMILES | CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C |
| Isomeric SMILES | C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C |
| PubChem CID | 10133 |
| Molecular Weight | 392.58 |
| PubChem CID | 10133 |
|---|---|
| DrugBank Ligand | DB06777 |
| Wikipedia | Chenodeoxycholic_acid |
| CAS Registry No. | 474-25-9 |
| ChEMBL Ligand | CHEMBL240597 |
| ChEBI | CHEBI:16755 |
| NURSA Ligand | 10.1621/H7NZZJBHW4 |
| RCSB PDB Ligand | JN3 |
| DrugCentral Ligand | 4361 |
| GPCRdb Ligand | chenodeoxycholic acid |
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| Sensitivity | Light sensitive. |
|---|
| Pictogram(s) | GHS08, GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled H361:Suspected of damaging fertility or the unborn child |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| Merck Index | 2054 |
I2118224