Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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C154015-50mg | 50mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $21.90 | |
C154015-200mg | 200mg | In stock | $65.90 | |
C154015-1g | 1g | In stock | $251.90 | |
C154015-5g | 5g | In stock | $1,132.90 | |
C154015-25g | 25g | In stock | $5,097.90 |
Nitrogen mustard alkylating agent
Synonyms | RCRA waste no. U035 | Chloorambucol | Elcoril | Linfolizin | 4-[Bis(2-chloroethyl)amino]benzenebutyric acid | Chloraminophen | NSC3088 | 4-(Bis(2-chloroethyl)amino)benzenebutanoic acid | 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid | Amboclorin | Ch |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Nitrogen mustard alkylating agent. Displays antineoplastic and immunosuppressant effect. Induces apoptosis in chronic lymphocytic leukaemia cells. Chemotherapeutic agent, highly mutagenic in male germ cells of the mouse. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | DNA inhibitor |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
ALogP | 1.7 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid |
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INCHI | InChI=1S/C14H19Cl2NO2/c15-8-10-17(11-9-16)13-6-4-12(5-7-13)2-1-3-14(18)19/h4-7H,1-3,8-11H2,(H,18,19) |
InChi Key | JCKYGMPEJWAADB-UHFFFAOYSA-N |
Canonical SMILES | C1=CC(=CC=C1CCCC(=O)O)N(CCCl)CCCl |
Isomeric SMILES | C1=CC(=CC=C1CCCC(=O)O)N(CCCl)CCCl |
RTECS | ES7525000 |
PubChem CID | 2708 |
UN Number | 2811 |
Packing Group | I |
Molecular Weight | 304.21 |
Reaxy-Rn | 999011 |
DrugBank Ligand | DB00291 |
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PubChem CID | 2708 |
CAS Registry No. | 305-03-3 |
ChEMBL Ligand | CHEMBL515 |
Wikipedia | Chlorambucil |
RCSB PDB Ligand | CBL |
PEP | chlorambucil |
DrugCentral Ligand | 588 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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B2006230 | Certificate of Analysis | Dec 14, 2023 | C154015 |
H2203209 | Certificate of Analysis | Jun 08, 2022 | C154015 |
H2203210 | Certificate of Analysis | Jun 08, 2022 | C154015 |
H2203211 | Certificate of Analysis | Jun 08, 2022 | C154015 |
H2303010 | Certificate of Analysis | Jun 08, 2022 | C154015 |
H2426264 | Certificate of Analysis | Jun 08, 2022 | C154015 |
Solubility | DMSO : ≥ 24 mg/mL (78.89 mM) |
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Sensitivity | heat sensitive |
Melt Point(°C) | 67 °C |
Pictogram(s) | GHS06, GHS08, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed H360:May damage fertility or the unborn child H350:May cause cancer |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
RTECS | ES7525000 |
Reaxy-Rn | 999011 |
Class | 6.1 |
Merck Index | 2073 |
1. Yi Zhang, Qingbo Deng, Chang Tang, Minglu Zhang, Zilong Huang, Zhifeng Cai. (2023) Fluorescent folic acid-capped copper nanoclusters for the determination of rifampicin based on inner filter effect. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 286 (121944). [PMID:36228492] [10.1016/j.saa.2022.121944] |
1. Yi Zhang, Qingbo Deng, Chang Tang, Minglu Zhang, Zilong Huang, Zhifeng Cai. (2023) Fluorescent folic acid-capped copper nanoclusters for the determination of rifampicin based on inner filter effect. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 286 (121944). [PMID:36228492] [10.1016/j.saa.2022.121944] |