Chloraseptin | Euclorina | Benzenesulfonamide, N-chloro-4-methyl-, sodium salt, trihydrate | Disifin | HALAMID AQUA | p-Toluenesulfonchloramide Sodium Salt | HY-U00087 | Sodium derivative of N-chloro-p-toluenesulfonamide trihydrate | CHLORAMINE-T TRIHYDRA
Specifications & Purity
ACS, ≥98%
Storage Temp
Protected from light,Argon charged
Shipped In
Normal
Grade
ACS
Product Description
Chloramine T (CAT) trihydrate is a commonly used reagent for organic synthesis especially in heterocyclic chemistry. CAT is an active chlorine compound that shows antimicrobial activity.
for the detection of halogens and bromate；Chloramine T trihydrate may be used as an oxidizing agent in the synthesis of 8-chloro-[1,2,4]triazolo[4,3-a]pyrazine derivatives and novel isoxazolines.
It may also be used in the synthesis of the following compounds:
· Nitrile imines by the oxidative dehydrogenation of N-(nitrobenzyl)-imidazole aldehyde hydrazine.
· Mono-N-tosylated-1,2-diamines.
· 3,5-Disubstituted isoxazoles.
· Fused 3,6-disubstituted triazolothiadiazoles by the oxidative cyclization of N-heteroaryl-substituted hydrazones.
Nitrene source for aziridinations and aminohydroxylations.
Associated Targets(Human)
EHMT2TchemHistone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
1.Yuedan Xu, Yi Sun, Wei Liu, Zhiwei Shi, Xinyang Jin, Jiawei Xu, Xinni Pan, Zhixin Zhang, Baiping Fu, Ling Zhang. (2023) Effects of an orthodontic primer containing amorphous fluorinated calcium phosphate nanoparticles on enamel white spot lesions. Journal of the Mechanical Behavior of Biomedical Materials, 137 (105567). [PMID:36379092]
References
1.G Li,K B Sharpless. (1996-08-01) Catalytic asymmetric aminohydroxylation provides a short taxol side-chain synthesis.. Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 50 ((8)):(649-651). [PMID:8756354]
2.Satoshi Minakata,Daisuke Kano,Yoji Oderaotoshi,Mitsuo Komatsu. (2003-12-25) Silica-water reaction media: its application to the formation and ring opening of aziridines.. Angewandte Chemie (International ed. in English), 43 ((1)):(79-81). [PMID:14694476]
3.G D Kishore Kumar,Sundarababu Baskaran. (2004-04-08) Heteropoly acid as a novel nitrene transfer agent: a facile and practical aziridination of olefins with Chloramine-T.. Chemical communications (Cambridge, England), (1026-1027). [PMID:15069527]
4.Maria Koufaki,Theano Fotopoulou,Marianna Kapetanou,Georgios A Heropoulos,Efstathios S Gonos,Niki Chondrogianni. (2014-07-06) Microwave-assisted synthesis of 3,5-disubstituted isoxazoles and evaluation of their anti-ageing activity.. European journal of medicinal chemistry, 83 (508-515). [PMID:24996137]
5.Heemin Kang,Yuze Zeng,Shyni Varghese. (2018-07-23) Functionally graded multilayer scaffolds for in vivo osteochondral tissue engineering.. Acta biomaterialia, 78 (365-377). [PMID:30031911]
6.M Nagl,V A Nguyen,W Gottardi,H Ulmer,R Höpfl. (2003-09-27) Tolerability and efficacy of N-chlorotaurine in comparison with chloramine T for the treatment of chronic leg ulcers with a purulent coating: a randomized phase II study.. The British journal of dermatology, 149 ((3)):(590-597). [PMID:14510994]
7.Kun Han,Yanting Zhang,Zhenwei Yang. (2019-03-15) Cilostazol protects rats against alcohol-induced hepatic fibrosis via suppression of TGF-β1/CTGF activation and the cAMP/Epac1 pathway.. Experimental and therapeutic medicine, 17 ((3)):(2381-2388). [PMID:30867723]
8.Yuedan Xu, Yi Sun, Wei Liu, Zhiwei Shi, Xinyang Jin, Jiawei Xu, Xinni Pan, Zhixin Zhang, Baiping Fu, Ling Zhang. (2023) Effects of an orthodontic primer containing amorphous fluorinated calcium phosphate nanoparticles on enamel white spot lesions. Journal of the Mechanical Behavior of Biomedical Materials, 137 (105567). [PMID:36379092]
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B2306797
